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Ace+Method+Development+Kits
Fournisseur:
G-Biosciences
Description:
Perfect-FOCUS™ is based on quantitative precipitation and concentration of protein solutions using UPPA™ (Universal Protein Precipitation Agent) and has been specifically developed for preparing lower conductivity protein samples for iso-electric focusing gels. Perfect-FOCUS™ is designed to clean and remove interfering agents from protein samples and concentrate protein solutions that give poor protein spot resolution during 2D electrophoresis.
Numéro de catalogue:
(BOSSBS-0052R-A350)
Fournisseur:
Bioss
Description:
Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, CASP7, CASP9 and CASP1. May participate in the GZMB apoptotic pathways. Cleaves ADPRT. Hydrolyzes the small-molecule substrate, Ac-Asp-Glu-Val-Asp-|-AMC. Likely target for the cowpox virus CRMA death inhibitory protein.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0052R-A555)
Fournisseur:
Bioss
Description:
Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, CASP7, CASP9 and CASP1. May participate in the GZMB apoptotic pathways. Cleaves ADPRT. Hydrolyzes the small-molecule substrate, Ac-Asp-Glu-Val-Asp-|-AMC. Likely target for the cowpox virus CRMA death inhibitory protein.
UOM:
1 * 100 µl
Numéro de catalogue:
(AATB72745)
Fournisseur:
AAT BIOQUEST INC
Description:
FastClick™ XFD750 Azide contains both the CAG moiety of FastClick (for assisting click efficiency) and Alexa Fluor® 750 fluorophore (as the fluorescence tag) for developing Alexa Fluor® 750-based fluorescent probes.
UOM:
1 * 1 mg
New Product
Fournisseur:
Ahlstrom-Munksjö
Description:
GenReleaz™ and GenReleaz™ Colour specimen collection cards are specifically developed for collection, transport, preservation and fast and efficient elution of DNA from biological fluids stored at ambient temperature.
Numéro de catalogue:
(PRSI25-431)
Fournisseur:
ProSci Inc.
Description:
TEAD2 contains 1 TEA DNA-binding domain. TEAD2 is a putative transcription factor that binds to the SPH and GT-IIC enhansons (5'-GTGGAATGT-3'). It may be involved in the gene regulation of neural development.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-556)
Fournisseur:
ProSci Inc.
Description:
LRRC8 is a multi-pass membrane protein. It contains 13 LRR (leucine-rich) repeats. LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-891)
Fournisseur:
ProSci Inc.
Description:
ADAM2 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM2 is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-820)
Fournisseur:
ProSci Inc.
Description:
SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterizedThis gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
UOM:
1 * 1 EA
Fournisseur:
STEMCELL Technologies
Description:
Heregulin-beta 1 also known as neuregulin-1 (NRG-1) is a member of the epidermal growth factor (EGF) family of growth factors and acts as a ligand for ErbB family receptor tyrosine kinases (Britsch <i>et al.</i>). Heregulin/neuregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3, and NRG4). Heregulin-beta 1 plays an important role during the development of the nervous system, heart, and mammary glands (Britsch). Heregulin-beta 1 is expressed in neuronal cells, and modulates cell growth and differentiation of the cells during development and wound healing (Mei and Xiong). It has been implicated through in vivo and in vitro studies that heregulin-beta 1/ErbB signaling is crucial for multiple aspects of cardiovascular development and protects the heart from ischemic injury (Odiete <i>et al.</i>). Heregulin-beta 1 also promotes invasiveness and metastasis of breast cancer cells (Hutcheson <i>et al.</i>). It has also been shown that heregulin-beta 1 has a role in the growth and maintenance of human embryonic stem cells (Wang <i>et al.</i>).
Numéro de catalogue:
(AATB2026)
Fournisseur:
AAT BIOQUEST INC
Description:
A thiol-reactive building block for developing a probe that can be recognized by anti-DNP antibodies; Also an excellent thiol-reactive FRET quencher paired with Trp or Tyr.
UOM:
1 * 25 mg
New Product
Numéro de catalogue:
(PRSI29-290)
Fournisseur:
ProSci Inc.
Description:
NOVA2 may regulate RNA splicing or metabolism in a specific subset of developing neurons. It binds single strand RNA.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI31-186)
Fournisseur:
ProSci Inc.
Description:
ETV6 (ETS-related protein Tel1, ETS translocation variant 6 , Tel) is an ETS family transcription factor. This protein contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-355)
Fournisseur:
ProSci Inc.
Description:
CMAS is an enzyme that catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-155)
Fournisseur:
ProSci Inc.
Description:
SYCP3 is a component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. It has an essential meiotic function in spermatogenesis. SYCP3 may be important for testis development.
UOM:
1 * 50 µG
Numéro de catalogue:
(USBIR9010-02-10L)
Fournisseur:
US Biological
Description:
RPMI-1640 was developed by Moore <i>et. al</i>. at Roswell Park Memorial Institute, hence the acronym RPMI.
UOM:
1 * 1 ST
New Product
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