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Ace+Method+Development+Kits
Numéro de catalogue:
(PRSI6383)
Fournisseur:
ProSci Inc.
Description:
TEKT5 Antibody: Tektins are insoluble alpha-helical proteins related to intermediate filament proteins and are essential for the assembly of cilia and flagella. Tektin-5 (TEKT5) is a recently identified member of the Tektin family. It is predominantly expressed in testis, and its expression is upregulated during testis development. It is present in sperm flagella but not in heads, suggesting that it may act as a middle component required for flagellar stability and sperm mobility.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI55-379)
Fournisseur:
ProSci Inc.
Description:
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. This gene encodes a protein initially considered to be a beta-crystallin but the encoded protein is monomeric and has greater sequence similarity to other gamma-crystallins. This gene encodes the most significant gamma-crystallin in adult eye lens tissue. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI25-048)
Fournisseur:
ProSci Inc.
Description:
GSC regulates chordin (CHRD). GSC may play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis.This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI33-453)
Fournisseur:
ProSci Inc.
Description:
Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterised by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognises target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(AATB13402)
Fournisseur:
AAT BIOQUEST INC
Description:
Ac-DEVD-AMC is a fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
UOM:
1 * 5 mg
New Product
Fournisseur:
MP Biomedicals
Description:
Potassium bromure ≥99.0%, poudre cristalline blanche ACS
Numéro de catalogue:
(PRSI30-290)
Fournisseur:
ProSci Inc.
Description:
LHX8 is a member of the LIM homeobox family. Members of this family share common structural features. They all contain 2 tandemly repeated cysteine-rich double-zinc finger motifs, called LIM domains, in addition to a homeodomain. The homeodomain is a DNA-binding domain, and the LIM domains are essential for regulating the activity of these molecules by interacting with other proteins. Members of the family are required for the patterning or the specification and differentiation of different cell types during embryonic development.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI27-452)
Fournisseur:
ProSci Inc.
Description:
The protein encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI29-104)
Fournisseur:
ProSci Inc.
Description:
OTP is a member of the homeodomain (HD) family. HD family proteins are helix-turn-helix transcription factors that play key roles in the specification of cell fates. This protein may function during brain development.This gene encodes a member of the homeodomain (HD) family. HD family proteins are helix-turn-helix transcription factors that play key roles in the specification of cell fates. This protein may function during brain development.
UOM:
1 * 50 µG
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