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Ace+Method+Development+Kits
Numéro de catalogue:
(PRSI5835)
Fournisseur:
ProSci Inc.
Description:
TCTN2 Antibody: TCTN2 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN2 is not known, it is 49% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
UOM:
1 * 1 EA
Numéro de catalogue:
(AATB50007)
Fournisseur:
AAT BIOQUEST INC
Description:
Semicarbazide (SEM)-BSA Conjugate is used for developing anti-Semicarbazide (SEM) antibodies that are typically used in an ELISA assay.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(PRSI31-263)
Fournisseur:
ProSci Inc.
Description:
PAX4 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box gene 4 is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing.- cells. This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments.
UOM:
1 * 50 µG
Numéro de catalogue:
(PROONIST-1884B)
Fournisseur:
LGC Standards PROMOCHEM
Description:
These are intended primarily for the evaluation and calibration of methods for analysis of cements and materials of similar matrix.
UOM:
1 * 5 ST
Numéro de catalogue:
(AATB50562)
Fournisseur:
AAT BIOQUEST INC
Description:
Fentanyl maleimide can be conveniently used to make biological conjugates of fentanyl that are used to develop fentanyl assays and tests.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(BOSSBS-3092R-A647)
Fournisseur:
Bioss
Description:
Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, GOLGA2/GM130, GRASP1, UBE2A/hHR6A, HIST1H1 proteins/histone H1, HMGA1, HIVEP3/KRC, LMNA, LMNB, LMNC, LBR, LATS1, MAP1B, MAP4, MARCKS, MCM2, MCM4, MKLP1, MYB, NEFH, NFIC, NPC/nuclear pore complex, PITPNM1/NIR2, NPM1, NCL, NUCKS1, NPM1/numatrin, ORC1, PRKAR2A, EEF1E1/p18, EIF3F/p47, p53/TP53, NONO/p54NRB, PAPOLA, PLEC/plectin, RB1, UL40/R2, RAB4A, RAP1GAP, RCC1, RPS6KB1/S6K1, KHDRBS1/SAM68, ESPL1, SKI, BIRC5/survivin, STIP1, TEX14, beta-tubulins, MAPT/TAU, NEDD1, VIM/vimentin, TK1, FOXO1, RUNX1/AML1, SIRT2 and RUNX2. CDK1/CDC2-cyclin-B controls pronuclear union in interphase fertilized eggs. Essential for early stages of embryonic development. During G2 and early mitosis, CDC25A/B/C-mediated dephosphorylation activates CDK1/cyclin complexes which phosphorylate several substrates that trigger at least centrosome separation, Golgi dynamics, nuclear envelope breakdown and chromosome condensation. Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1- and PKMYT1-mediated phosphorylation to allow sister chromatid separation, chromosome decondensation, reformation of the nuclear envelope and cytokinesis. Inactivated by PKR/EIF2AK2- and WEE1-mediated phosphorylation upon DNA damage to stop cell cycle and genome replication at the G2 checkpoint thus facilitating DNA repair.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3092R)
Fournisseur:
Bioss
Description:
Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, GOLGA2/GM130, GRASP1, UBE2A/hHR6A, HIST1H1 proteins/histone H1, HMGA1, HIVEP3/KRC, LMNA, LMNB, LMNC, LBR, LATS1, MAP1B, MAP4, MARCKS, MCM2, MCM4, MKLP1, MYB, NEFH, NFIC, NPC/nuclear pore complex, PITPNM1/NIR2, NPM1, NCL, NUCKS1, NPM1/numatrin, ORC1, PRKAR2A, EEF1E1/p18, EIF3F/p47, p53/TP53, NONO/p54NRB, PAPOLA, PLEC/plectin, RB1, UL40/R2, RAB4A, RAP1GAP, RCC1, RPS6KB1/S6K1, KHDRBS1/SAM68, ESPL1, SKI, BIRC5/survivin, STIP1, TEX14, beta-tubulins, MAPT/TAU, NEDD1, VIM/vimentin, TK1, FOXO1, RUNX1/AML1, SIRT2 and RUNX2. CDK1/CDC2-cyclin-B controls pronuclear union in interphase fertilized eggs. Essential for early stages of embryonic development. During G2 and early mitosis, CDC25A/B/C-mediated dephosphorylation activates CDK1/cyclin complexes which phosphorylate several substrates that trigger at least centrosome separation, Golgi dynamics, nuclear envelope breakdown and chromosome condensation. Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1- and PKMYT1-mediated phosphorylation to allow sister chromatid separation, chromosome decondensation, reformation of the nuclear envelope and cytokinesis. Inactivated by PKR/EIF2AK2- and WEE1-mediated phosphorylation upon DNA damage to stop cell cycle and genome replication at the G2 checkpoint thus facilitating DNA repair.
UOM:
1 * 100 µl
Numéro de catalogue:
(AATB128)
Fournisseur:
AAT BIOQUEST INC
Description:
FAM cadaverine is an excellent building block for developing fluoresceinated bioconjugates.
UOM:
1 * 100 mg
New Product
Numéro de catalogue:
(STMC100-1407)
Fournisseur:
STEMCELL Technologies
Description:
Stimulating T cells with Candida (MP65) peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. Candida peptide pool is a lyophilised mixture of 92 peptides from the mannoprotein MP65 of Candida albicans (yeast), and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 379 on MP65. MP65 contributes to cell wall integrity and epithelia adherence (Sandini <i>et al.</i>), and is a potent T cell immunogen (Gomez <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
UOM:
1 * 1 PE
New Product
 Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Numéro de catalogue:
(PRSI33-982)
Fournisseur:
ProSci Inc.
Description:
CD56/NCAM is a cell adhesion protein which is a member of the immunoglobulin superfamily. It is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. CD56 has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. [UniProt].
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(MIEL12506230)
Fournisseur:
MIELE
Description:
Le PG 8504 est une unité sur pied avec couvercle et boîtier extérieur en acier inoxydable. Il relève de nombreux défis en matière de nettoyage dans les environnements de laboratoire. Sa capacité améliorée permet de nettoyer rapidement un grand nombre d'ustensiles et d'équipements.
UOM:
1 * 1 ST
New Product
Numéro de catalogue:
(PRSI31-267)
Fournisseur:
ProSci Inc.
Description:
SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.
UOM:
1 * 50 µG
Numéro de catalogue:
(AATB23071)
Fournisseur:
AAT BIOQUEST INC
Description:
Congo Red has been used as a common qualitative staining method for the identification of amyloids in vitro and in tissue sections.
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(PRSI27-815)
Fournisseur:
ProSci Inc.
Description:
Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI27-651)
Fournisseur:
ProSci Inc.
Description:
HMX1 acts as a transcriptional antagonist and is part of the Hmx family of homeodomain proteins which are predominately expressed in discrete regions of developing sensory tissues.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI26-246)
Fournisseur:
ProSci Inc.
Description:
TCF25 acts as a transcriptional repressor. It has been shown to repress transcription of SRF in vitro and so may play a role in heart development.
UOM:
1 * 50 µG
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