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Fournisseur:  DWK Life Sciences
Description:   The E-Z Crimper™ crimpers are used to attach aluminium seals to bottles and vials with a crimp or serum finish.
Numéro de catalogue: (PRSI2491)

Fournisseur:  ProSci Inc.
Description:   KappaB ras Antibody: KappaB ras-1 ( kappa B-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with I kappa B (I kappa B), an inhibitor of the transcription factor NF-kappa B. I kappa B exists in two homologous forms, I kappa B-alpha and I kappa B-beta, although I kappa B-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive I kappa B-alpha-NF-kappa B complexes can shuttle in and out of the nucleus, I kappa B-beta-NF-kappa B complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the I kappa B-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of I kappa B-beta and regulating the rate of degradation of I kappa B-beta. This antibody detects both kappaB-ras1 and kappaB-ras2.
UOM:  1 * 1 EA
Fournisseur:  U-Power
Description:   Safety ankle boots made from extra strong canvas with soft suede leather inserts and a slip-resistant dual-density PU sole.
Fournisseur:  EP SCIENTIFIC
Description:   These straight sided wide-mouth HDPE jar allows for easy filling and sample retreival. Recommended for collecting soil, sediment and sludge samples to be analyzed for inorganic trace analytes.
Environmentally Preferable
Fournisseur:  DWK Life Sciences
Description:   Wheaton CryoELITE® Cryogenic Freestanding Vials have a Loctagon™ Vial Skirt that provides stability in the freestanding position and locks into the CryoELITE® Benchmate Rack in order to provide easy open and close with one hand.
Fournisseur:  HAMILTON BONADUZ
Description:   Ces pointes sont validées afin d'optimiser les performances du système Microlab 300, offrant une exactitude et une précision supérieures. Lorsque les pointes sont placées sur la sonde, le joint torique de la sonde s'insère dans la rainure de la pointe. Cette conception ne requiert qu'une faible force d'insertion pour charger correctement une pointe : l'utilisateur bénéficie alors d'une ergonomie accrue et d'une utilisation à long terme moins fatigante.
Numéro de catalogue: (OPTKIM-300FL4)

Fournisseur:  OPTIKA
Description:   Advanced inverted microscope for brightfield and fluorescence observations with Semi-Apo IOS LWD U-PLAN F objectives to enhance the visibility of the sample and increase the overall contrast.
UOM:  1 * 1 Un.
New Product
Fournisseur:  HUBER
Description:   Ces circulateurs réfrigérés compacts avec bains de réfrigération isolés sont parfaits pour le contrôle direct de la température de –90 à +200 °C. Le faible volume du bain et la capacité de chauffage et de refroidissement élevée signifient que la durée de chauffage/refroidissement est courte. Il est encore possible de raccourcir celle-ci en utilisant les garnitures de déplacements (en option). Les garnitures de calibrage (en option) permettent aux circulateurs de servir de bains de calibrage.

Fournisseur:  Thermo Fisher Scientific
Description:   Transport and universal containers have passed the 95 kPa test described in UN packaging instructions 602/650 for transport of infectious substances and diagnostic specimens (except 391-8326). Universal containers are maximum RCF tested (RCF=Relative Centrifugal Force). Caps designed to avoid droplets adhering to the surface giving reduced risk of aerosols.
UOM:  1 * 400 ST
Numéro de catalogue: (PRSI28-518)

Fournisseur:  ProSci Inc.
Description:   Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI2495)

Fournisseur:  ProSci Inc.
Description:   KappaB ras2 Antibody: KappaB ras-1 ( kappa B-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with I kappa B (I kappa B), an inhibitor of the transcription factor NF-kappa B. I kappa B exists in two homologous forms, I kappa B-alpha and I kappa B-beta, although I kappa B-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive I kappa B-alpha-NF-kappa B complexes can shuttle in and out of the nucleus, I kappa B-beta-NF-kappa B complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the I kappa B-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of I kappa B-beta and regulating the rate of degradation of I kappa B-beta. This antibody is specific for kappaB-ras2 and has no cross-reactivity to kappaB-ras1.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI55-794)

Fournisseur:  ProSci Inc.
Description:   This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI3023)

Fournisseur:  ProSci Inc.
Description:   Bcl-rambo Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains. A novel, widely expressed member termed Bcl-rambo was recently identified. This protein is localized to mitochondria in mammalian cells and its overexpression induces apoptosis which could be blocked by co-expression of inhibitor of apoptosis proteins (IAPs) such as XIAP, cIAP1, and cIAP2. Bcl-rambo shows overall homology to the anti-apoptotic members containing BH motifs, but unlike Bcl-2, the C-terminal membrane anchor of Bcl-rambo is preceded by a unique 250 amino acid insertion. This region by itself can induce apoptosis more efficiently than the Bcl-2 homology regions, suggesting that Bcl-rambo may be important other pro-apoptotic pathways.
UOM:  1 * 1 EA
Fournisseur:  BEHR
Description:   SG 6/B, Cadre de positionnement pour 6×SR 2 dans SMA 6 ou SMA 6/HT
Numéro de catalogue: (PRSI79-518)

Fournisseur:  ProSci Inc.
Description:   Tau is a heterogeneous microtubule-associated protein that promotes and stabilizes microtubule assembly, especially in axons. Six isoforms with different amino-terminal inserts and different numbers of tandem repeats near the carboxy-terminus have been identified, and tau is hyperphosphorylated at approximately 25 sites by ERK, GSK-3 and CDK5. Phosphorylation decreases the ability of tau to bind to microtubules. Neurofibrillary tangles are a major hallmark of Alzheimer's disease and these tangles are bundles of paired helical filaments composed of hyperphosphorylated tau. In particular, phosphorylation of Ser396 by GSK-3 or CDK5 destabilizes microtubules in Alzheimer's disease. Furthermore, inclusions of tau are found in a number of other neurodegenerative diseases, collectively known as tauopathies (1, 3).
UOM:  1 * 1 EA
Fournisseur:  Restek
Description:   Microseal septum incorporates two separate sealing mechanisms. These sliding seals eliminate septum coring and the resulting accumulation of septum crumbs in the injection port liner. The septum uses a 23-gauge (0,63 mm, 0,025”) needle or probe with a blunt, truncated conical tip. Since the syringe plunger end details are determined by manual or autosampler compatibility. The advantages of the septum include elimination of septum coring, longer life, consistent and low needle insertion force.
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