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Masterflex+Single-use
Numéro de catalogue:
(PRSI56-066)
Fournisseur:
ProSci Inc.
Description:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(661-0210)
Fournisseur:
Mettler - Toledo
Description:
Le titrimètre volumétrique KF est parfait pour la détermination rapide et précise de la teneur en eau tout en étant très simple d'utilisation. Les échantillons ayant une teneur en eau comprise entre 100 ppm et 100% sont analysés par le biais de mesures uniques ou en tant que séries d'échantillons comportant des statistiques.
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI33-094)
Fournisseur:
ProSci Inc.
Description:
The antibody recognises a single chain glycoprotein of 105/120 kDa, identified as CD30/Ki-1. CD30 is synthesised as a 90 kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120 kDa glycoprotein. In Hodgkin’s disease, CD30 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This antibody distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the CD30 positive lymphomas lack the leukocyte common antigen (CD45).
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI55-070)
Fournisseur:
ProSci Inc.
Description:
Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived from this gene are present in the genome.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI56-128)
Fournisseur:
ProSci Inc.
Description:
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI6763)
Fournisseur:
ProSci Inc.
Description:
RNASET2 Antibody: RNASET2 is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement, and has been suggested to function as a tumor suppressor protein. Its expression is suppressed in Human T-cell Leukemia Virus type 1 (HTLV-1) infected cells following the binding of the HTLV-1 Tax protein to the RNASET2 promoter. As Adult T-cell leukemia (ATL) is one of the primary diseases caused by HTLV-1 infection, a reduction in the level of RNASET2 by Tax may play a role in ATL development.
UOM:
1 * 1 EA
Fournisseur:
iST Scientific Ltd
Description:
Feuille de haute qualité, perforable et décollable, pour plaques de polystyrène avec une bonne résistance aux solvants, notamment le DMSO. Idéale pour le stockage de composés à basse température, PCR, pour le stockage de composés à température ambiante et à court terme.
Fournisseur:
Portwest
Description:
Ces chaussures de sécurité polyvalentes, en microfibre de grande qualité, sont résistantes, hydrofuges et lavables en machine.
Numéro de catalogue:
(PRSI91-294)
Fournisseur:
ProSci Inc.
Description:
SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-cell lines. Although the cytoplasmic domain of CS1 contains immunoreceptor tyrosine-based switch motifs (ITSM), which enables to recruite signaling lymphocyte activation molecule (SLAM)-associated protein (SAP/SH2D1A), it activates NK cells in the absence of a functional SAP. SLAMF7 positively regulated natural killer cell functions by a mechanism dependent on the adaptor EAT-2 but not the related adaptor SAP. However, in the absence of EAT-2, CRACC potently inhibited natural killer cell function. It was also inhibitory in T cells, which are typically devoid of EAT-2. Thus, SLAMF7 can exert activating or inhibitory influences on cells of the immune system depending on cellular context and the availability of effector proteins.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-287)
Fournisseur:
ProSci Inc.
Description:
VCAM-1 is a single-pass type I membrane protein, contains 7 Ig-like C2-type domains. It is an endothelial ligand for very late antigen-4 (VLA-4) and alpha4ß7 integrin expressed on leukocytes, and thus mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 expression is induced on endothelial cells during inflammatory bowel disease, atherosclerosis, allograft rejection, infection, and asthmatic responses. During these responses, VCAM-1 forms a scaffold for leukocyte migration. VCAM-1 also activates signals within endothelial cells resulting in the opening of an "endothelial cell gate" through which leukocytes migrate. VCAM-1 has been identified as a potential anti-inflammatory therapeutic target, the hypothesis being that reduced expression of VCAM-1 will slow the development of atherosclerosis. In addition, VCAM-1-activated signals in endothelial cells are regulated by cytokines indicating that it is important to consider both endothelial cell adhesion molecule expression and function during inflammatory processes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-508)
Fournisseur:
ProSci Inc.
Description:
Mouse interleukin-16(IL-16) is a single chain non-glycosylated polypeptide. IL-16 is widely expressed in human tissues including spleen, thymus, lymph nodes, peripheral leukocytes, bone marrow and cerebellum. IL-16 plays an important role instimulating a migratory response in CD4+ lymphocytes, monocytes, and eosinophils,inducing T-lymphocyte expression of interleukin 2 receptor.It was originally identified as a CD8+ T cell-derived chemoattractant for CD4+ cells. In addition to its chemotactic properties, IL-16 has also been shown to suppress HIV-1 replication in vitro and appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. It may act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
UOM:
1 * 50 µG
Fournisseur:
Greiner Bio-One
Description:
En éthylène-acétate de vinyle (EVA) ou silicone, CapMats offrir une méthode alternative pour la fermeture de microplaques à 96 et 384 puits. Tous les tapis de fermeture sont exempts de RNase, de DNase et d'ADN humain, apyrogènes, et adaptés aux applications PCR.
Fournisseur:
EPPENDORF
Description:
La pipette électronique Xplorer®, simple et précise, est spécialement conçue pour répondre aux exigences professionnelles.
Numéro de catalogue:
(PRSI28-774)
Fournisseur:
ProSci Inc.
Description:
FOXJ1 is a member of forkhead/winged-helix transcription factor family, which play crucial roles during vertebrate development. FOXJ1 may play an important role in cell fate determination during lung development and in spermatogenesis.The unique pattern of FOXJ1expression during human fetal development suggests a role for this forkhead/winged-helix factor during pulmonary and renal epithelial development. Single nucleotide polymorphisms were identified in FOXJ1 and a significant association was found with allergic rhinitis.FOXJ1 is a member of the forkhead gene family, which was originally identified in Drosophila. The forkhead family is composed of transcription factors with a conserved 100-amino acid DNA-binding motif.FOXJ1 is a member of the forkhead gene family, which was originally identified in Drosophila. The forkhead family is composed of transcription factors with a conserved 100-amino acid DNA-binding motif.
UOM:
1 * 50 µG
Fournisseur:
Lovibond Tintometer
Description:
Lovibond® System 3000 est une série d'appareils à échelle unique et 3 champs pour déterminer la couleur d'un échantillon par classement visuel, obtenu par comparaison directe de l'échantillon aux étalons en verre de couleur. Le champ de vision en 3 sections permet de voir simultanément l'échantillon et 2 verres consécutifs sur l'échelle colorimétrique, ce qui facilite l'identification de la couleur la plus concordante. Afin de détecter rapidement une couleur dans un cadre de limites colorimétriques prédéterminées, les verres peuvent être réglés sur les 2 couleurs marquant la limite; il est alors facile de voir si l'échantillon se situe dans la zone de tolérance.
Numéro de catalogue:
(PRSI4805)
Fournisseur:
ProSci Inc.
Description:
Akirin2 Antibody: The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-kappa B-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kappa B pathways. Akirin1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1 beta signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.
UOM:
1 * 1 EA
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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