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Masterflex+Single-use+Flow+Sensor
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Masterflex+Single-use+Flow+Sensor
Numéro de catalogue:
(30050.)
Fournisseur:
Biotium
Description:
Cell proliferation dyes diffuse passively into cells and covalently label intracellular proteins, resulting in long term cell labelling. They are non-fluorescent until they are hydrolysed by intracellular esterase's. The dyes then react with intracellular amines forming fluorescent conjugates that are retained in the cell. Immediately after staining, a single, bright fluorescent population will be detected by flow cytometry. With each cell division, daughter cells inherit roughly half of the fluorescent label, allowing the number of cell divisions that occur after labelling to be detected by the appearance of successively dimmer fluorescent peaks on a flow cytometry histogram compared to cells analysed immediately after staining. Staining is formaldehyde fixable.
UOM:
1 * 1 KIT
Numéro de catalogue:
(BOSSBS-9491R-A555)
Fournisseur:
Bioss
Description:
The SOSS (Sensor of single-strand DNA) complex consists of multiple proteins that promote DNA repair and G2/M checkpoint downstream of the MRN (Mre11, Rad50 and Nbs1) complex. The complex is composed of SSBP1, INTS3 and C9orf80. Specifically, the SOSS complex binds to ssDNA at DNA lesions that influences diverse endpoints in the cellular DNA damage response. The complex is required for efficient homologous recombination-dependent repair of double-stranded breaks and ATM-dependent signaling pathways. C9orf80, also known as SOSS complex subunit C and Single-stranded DNA-binding protein-interacting protein 1 (SSBIP1), is a 104 amino acid nuclear protein that is a component of the SOSS complex. Upon DNA damage, C9orf80 along with other components of the SOSS complex migrate to the nucleus. There are two isoforms of C9orf80 that are produced as a result of alternative splicing events.
UOM:
1 * 100 µl
Fournisseur:
Avantor Fluid Handling
Description:
Compact size mounting rod—use these pumps almost anywhere.
Fournisseur:
Avantor Fluid Handling
Description:
Make the most of your Masterflex® pump with connection cables, replacement parts, and other accessories.
Numéro de catalogue:
(MFLX77931-10)
Fournisseur:
Avantor Fluid Handling
Description:
Use where electrical power is unsafe or unavailable.
UOM:
1 * 1 ST
Numéro de catalogue:
(MFLX07523-98)
Fournisseur:
Avantor Fluid Handling
Description:
Use to securely elevate front-end of digital drive.
UOM:
1 * 1 ST
Fournisseur:
Hach
Description:
These lightweight samplers with low power requirements (12 VDC) have been designed for easy mobility.
Numéro de catalogue:
(BERTD05717.20EA)
Fournisseur:
Bertin Instruments
Description:
<B>Optimiser la dissociation des tissus:</B> Le Kit de Dissociation Multi-Tissus Precellys développé par Bertin Technologies est une solution innovante et brevetée conçue pour l'obtention de cellules uniques viables à partir d'échantillons biologiques à des fins de recherche. Il permet l'obtention de cellules uniques de haute qualité à partir de tissus complexes tels que la rate, le foie, le poumon, le cœur et le thymus de souris et ouvre la voie à l'analyse de cellules uniques en aval, telle que la cytométrie de flux ou la NGS.
UOM:
1 * 1 KIT
New Product
Numéro de catalogue:
(BOSSBS-6634R-A750)
Fournisseur:
Bioss
Description:
Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. <i>in vitro</i>, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM:
1 * 100 µl
Fournisseur:
Avantor Fluid Handling
Description:
Ideal for use with high-purity or corrosive fluids.
Fournisseur:
Avantor Fluid Handling
Description:
Long life tubing for any Masterflex® pump used in your pharma and bioprocess applications.
Fournisseur:
Avantor Fluid Handling
Description:
Specifically designed for Masterflex® pump tubing.
Fournisseur:
Avantor Fluid Handling
Description:
Use with L/S® multichannel cartridge pump heads for synchronous, multichannel pumping.
Fournisseur:
Avantor Fluid Handling
Description:
Specifically designed for use with hydrocarbons, petroleum products and distillates.
Numéro de catalogue:
(MFLX07569-00)
Fournisseur:
Avantor Fluid Handling
Description:
Use where electrical power is unsafe or unavailable.
UOM:
1 * 1 ST
Fournisseur:
Avantor Fluid Handling
Description:
Use with caustic and high-purity liquids in many applications.
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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