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Fournisseur:  PerkinElmer
Description:   Single element standard is supplied with a comprehensive Certificate of Analysis that documents the quality and reliability.
UOM:  1 * 1 ST
Numéro de catalogue: (AGLSG2939BA)

Fournisseur:  AGILENT
Description:   Sizing, quantification, and sample quality control of DNA, RNA, and proteins on a single platform.
UOM:  1 * 1 ST
Numéro de catalogue: (PRSI26-218)

Fournisseur:  ProSci Inc.
Description:   SUSD4 contains 4 Sushi (CCP/SCR) domains. It is a single-pass type I membrane protein. The function of the SUSD4 protein remains unknown.
UOM:  1 * 50 µG
Numéro de catalogue: (HEATHD27515A)

Fournisseur:  HEATHROW
Description:   These durable racks are molded in a single, continuous piece so no assembly required and there are no detachable pieces.
UOM:  1 * 8 ST

Fournisseur:  Bioss
Description:   NCS-1 (for neuronal calcium sensor-1, also designated frequenin) belongs to a highly conserved family of EF-hand-containing Ca++-binding proteins expressed mainly in neurons. NCS-1 is localized to neuronal cell bodies and axons throughout the brain and spinal cord. It is also expressed in glial cells and in neuroendocrine bovine adrenal chromaffin and PC12 cells. NCS-1 is a regulatory protein involved in Ca++-dependent exocytosis of synaptic vesicles and dense core granules. NCS-1 also functions in the voltage-independent autocrine pathway that negatively regulates non-L-type Ca++ channels.
UOM:  1 * 100 µl
Fournisseur:  AAT BIOQUEST INC
Description:   6-FAM, SE is the amine-reactive succinimidyl ester of single isomer 6-FAM acid.
New Product
Fournisseur:  HAMMACHER KARL
Description:   Single-ended stirring spatulas made of WIRONIT stainless steel.
Fournisseur:  HAMMACHER KARL
Description:   Single-ended micro spatulas made from WIRONIT steel.
Fournisseur:  VWR Chemicals
Description:   Purification d'ADN simple ou double brin à partir de PCR ou d'autres réactions enzymatiques.
Numéro de catalogue: (BOSSBS-9022R-A647)

Fournisseur:  Bioss
Description:   IQCG is a 443 amino acid protein containing one IQ domain. Widely distributed in nature, the IQ domain forms an amphiphilic seven-turn α-helix capable of binding calmodulin in a Ca2+-independent manner. The level of intracellular calcium is tightly regulated in all eukaryotic cells. A modest increase in this level can result in a myriad of physiological responses, most of which are mediated by calmodulin (CaM), the universal calcium sensor. In acute T-lymphoid/myeloid leukemia, IQCG forms a complex with Nup98, an O-linked glycoprotein and a component of the nuclear pore complex. NUP98-IQCG complex bind co-activators and/or co-repressors, which suggest a role in transcriptional regulation.Nup98-IQCG complex inhibits 32Dcl3 cell apoptosis induced by Arabinofuranosylcytosine (Ara-C) and partially blocks granulocyte differentiation induced by G-CSF. IQCG exists as two isoforms due to alternatively splicing events.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-9022R-A555)

Fournisseur:  Bioss
Description:   IQCG is a 443 amino acid protein containing one IQ domain. Widely distributed in nature, the IQ domain forms an amphiphilic seven-turn α-helix capable of binding calmodulin in a Ca2+-independent manner. The level of intracellular calcium is tightly regulated in all eukaryotic cells. A modest increase in this level can result in a myriad of physiological responses, most of which are mediated by calmodulin (CaM), the universal calcium sensor. In acute T-lymphoid/myeloid leukemia, IQCG forms a complex with Nup98, an O-linked glycoprotein and a component of the nuclear pore complex. NUP98-IQCG complex bind co-activators and/or co-repressors, which suggest a role in transcriptional regulation.Nup98-IQCG complex inhibits 32Dcl3 cell apoptosis induced by Arabinofuranosylcytosine (Ara-C) and partially blocks granulocyte differentiation induced by G-CSF. IQCG exists as two isoforms due to alternatively splicing events.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-3686R-A350)

Fournisseur:  Bioss
Description:   Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes. EGLN1 is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality. Target proteins are preferencially recognized via a LXXLAP motif.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-3686R-CY5.5)

Fournisseur:  Bioss
Description:   Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes. EGLN1 is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality. Target proteins are preferencially recognized via a LXXLAP motif.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-9022R-A680)

Fournisseur:  Bioss
Description:   IQCG is a 443 amino acid protein containing one IQ domain. Widely distributed in nature, the IQ domain forms an amphiphilic seven-turn -helix capable of binding calmodulin in a Ca2+-independent manner. The level of intracellular calcium is tightly regulated in all eukaryotic cells. A modest increase in this level can result in a myriad of physiological responses, most of which are mediated by calmodulin (CaM), the universal calcium sensor. In acute T-lymphoid/myeloid leukemia, IQCG forms a complex with Nup98, an O-linked glycoprotein and a component of the nuclear pore complex. NUP98-IQCG complex bind co-activators and/or co-repressors, which suggest a role in transcriptional regulation.Nup98-IQCG complex inhibits 32Dcl3 cell apoptosis induced by Arabinofuranosylcytosine (Ara-C) and partially blocks granulocyte differentiation induced by G-CSF. IQCG exists as two isoforms due to alternatively splicing events.
UOM:  1 * 100 µl

Fournisseur:  THERMO SAVANT EC
Description:   Thermo Scientific™ Savant™ SpeedVac™ SPD2030 vacuum concentrators are fully integrated systems that combine a concentrator, refrigerated cold trap, diaphragm pump and a vacuum gauge into a single, compact unit.
UOM:  1 * 1 KIT
Numéro de catalogue: (HAMMHWN008-04)

Fournisseur:  HAMMACHER KARL
Description:   Single-ended spoon spatula made from WIRONIT steel.
UOM:  1 * 1 ST
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