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Single-use+Pressure+Sensor
Fournisseur:
FRISTADS KANSAS GROUP
Description:
T-shirt with short sleeves, manufatured from 100% pre-shrunk, ring spun cotton (single jersey). The models in colour grey melange are made of 85% cotton and 15% viscose.
Numéro de catalogue:
(PRSI96-478)
Fournisseur:
ProSci Inc.
Description:
Interleukin-6 receptor subunit beta (IL6ST) is also known as IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, Interleukin-6 signal transducer, Membrane glycoprotein 130 (gp130), CD130, Oncostatin-M receptor subunit alpha and Il6st,which is single-pass type I membrane protein. IL6ST /gp130 /CD130 can be found in tissues such as brain, heart, thymus, spleen, kidney, lung and liver and found in all the cell lines tested except BaF-B03.The expression of IL-6ST /gp130 is not restricted to IL6-responsive cells. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. IL6ST /CD130 can bind to IL6 /IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduce the signal. IL6ST /GP130 does not bind IL6 and may have a role in embryonic development.
UOM:
1 * 1 EA
Fournisseur:
Hach
Description:
Électrodes combinées de pH en laboratoire 3 en 1 avec un capteur de température intégré.
Fournisseur:
Portwest
Description:
This single colour bib and brace has the features and benefits of the tried and tested S488 contrast bib and brace in a choice of two colours.
Numéro de catalogue:
(BE-201)
Fournisseur:
G-Biosciences
Description:
Ce kit enseigne les techniques de manipulation aseptiques et la culture de bactéries en milieu de culture liquide et sur des plaques de gélose en phase solide. Ce kit est conçu pour éduquer les étudiants aux différentes étapes du cycle de prolifération bactérienne, à savoir temps mort, phases logarithmique ou exponentielle, stationnaire et dégénérescente ou mort. Ce kit traite également de l'importance de la prolifération des bactéries sur des plaques de gélose en phase solide pour isoler des colonies uniques de bactéries. Cette activité de laboratoire passe par la préparation d'un milieu de culture et de plaques de gélose solide.
UOM:
1 * 1 KIT
Numéro de catalogue:
(662-1374)
Fournisseur:
SI Analytics
Description:
Électrode à double broche en platine, dotée d'une tige en verre et de 2 capteurs en fil de platine (Ø 1 mm). Pour la détection de brome par titrage potentiométrique conformément à la norme ASTM.
UOM:
1 * 1 ST
Numéro de catalogue:
(BOSSBS-10994R-A680)
Fournisseur:
Bioss
Description:
Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localisation of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, c-myc/MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate TP53/p53 in the presence of supercoiled DNA is dependent on C1D.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10994R-FITC)
Fournisseur:
Bioss
Description:
Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, c-myc/MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate TP53/p53 in the presence of supercoiled DNA is dependent on C1D.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI91-941)
Fournisseur:
ProSci Inc.
Description:
Ephrin-B2 is a single-pass type I membrane protein and it contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-B2 belongs to the ephrin (EPH) family and it is cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. The ephrins and EPH-related receptors contain the largest subfamily of receptor protein-tyrosine kinases and have been associated with mediating developmental events, particularly in the nervous system and in erythropoiesis. Based upon their structures and sequence relationships, ephrins are allocated into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. It also binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4 and together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-513)
Fournisseur:
ProSci Inc.
Description:
CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. CD19 primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. CD19 Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) which is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen.
UOM:
1 * 50 µG
Numéro de catalogue:
(181-1031)
Fournisseur:
VACUUBRAND
Description:
Versatile, accurate and robust vacuum gauge. Outstanding measurement accuracy thanks to its capacitive, anti-corrosive gauge head with excellent long-term stability and effective temperature compensation. With its robust plastic housing and splash-proof gauge head, the VSK 3000 is ideal for tough applications.
UOM:
1 * 1 ST
Fournisseur:
STEMCELL Technologies
Description:
Fractalkine (CX3CL1) is a unique chemokine belonging to the CX3C family, and is characterized by a C-X3-C cysteine motif within the chemokine domain, near the amino terminus of the protein (Bazan <i>et al.</i>). The chemokine domain is connected to an extended mucin-like stalk, followed by a transmembrane region, and a C-terminal intracellular domain (Imai <i>et al.</i>; Jones <i>et al.</i>). The protein signals through interaction with a single receptor, CX3CR1, expressed on monocytes, natural killer cells, T cells, microglia, and smooth muscle cells. Fractalkine is upregulated in endothelial cells by inflammatory signals and is synthesized as a membrane-bound molecule that mediates cell migration and adhesion (White and Greaves). Cleavage at the base of the stalk by metalloproteinases generates a soluble chemokine, which functions as a potent chemoattractant of target cells (Garton <i>et al.</i>; Apostolakis and Spandidos). Fractalkine has been implicated in pathology of inflammatory diseases, such as atherosclerosis and other vascular diseases, and has anti-apoptotic functions (White and Greaves).
Fournisseur:
iST Scientific Ltd
Description:
Film perméable aux gaz, transparent et perforé pour les plaques en PP, PE, PS et COC. Idéal pour l'incubation à court terme, l'agriculture et le stockage de semences, le stockage d'insectes, les cultures cellulaires.
Numéro de catalogue:
(736-0354)
Fournisseur:
Greiner Bio-One
Description:
AMPLIseal™ est un film de scellage auto-adhésif qui se distingue par sa faible autofluorescence, notamment dans la gamme de longueurs d'onde critique pour la PCR en temps réel. Il est constitué d'un film épais en PP recouvert d'un adhésif transparent en acrylate. La couche adhésive est protégée par un film décollable en polyester. L'adhésif en acrylate à forte adhérence offre un scellage fiable qui limite l'évaporation, sans pour autant perturber la réaction PCR ou les mesures de fluorescence.
UOM:
1 * 100 ST
Numéro de catalogue:
(PRSI96-138)
Fournisseur:
ProSci Inc.
Description:
CD antigen CD98 is also known as 4F2 cell-surface antigen heavy chain (4F2hc), 4F2 heavy chain antigen, Solute carrier family 3 member 2 (SLC3A2), Lymphocyte activation antigen 4F2 large subunit, is a single-pass type I I membrane protein which belongs to the SLC3A transporter family.. SLC3A2 / CD98 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. SLC3A2 / CD98 is required for the function of light chain amino-acid transporters and also involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. CD98 involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A5 or SLC7A8, CD98 involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals.
UOM:
1 * 1 EA
Fournisseur:
DWK Life Sciences
Description:
DURAN®, verre borosilicaté 3,3, transparent, rodé, sans clé.
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