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Single-use+Temperature+Sensor
Numéro de catalogue:
(PRSI91-436)
Fournisseur:
ProSci Inc.
Description:
Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells(PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI79-548)
Fournisseur:
ProSci Inc.
Description:
The scaffolding protein encoded by Caveolin-1 is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI33-554)
Fournisseur:
ProSci Inc.
Description:
Recognises a protein of 75 kDa, identified as gamma heavy chain of human immunoglobulins. It reacts with all sub-classes of gamma chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI34-116)
Fournisseur:
ProSci Inc.
Description:
Recognises a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(BOSSBS-3225R-CY5)
Fournisseur:
Bioss
Description:
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq]. Hsp27, also referred to as the Estrogen regulated 24K protein and HSP28, is one of several small heat shock proteins (HSP) produced by all organisms studied. Hsp27 synthesis is induced by elevated temperature, as well as estrogen in hormone responsive cells. This protein is involved in stress resistance and actin organization. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSP's and mammalian a-crystalline lens protein. Because of the estrogen responsive nature of Hsp27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. This work has led to the suggestion that Hsp27 may be a useful marker in classifying various hormone sensitive tumors.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3180R)
Fournisseur:
Bioss
Description:
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq].Hsp27, also referred to as the Estrogen regulated 24K protein and HSP28, is one of several small heat shock proteins (HSP) produced by all organisms studied. Hsp27 synthesis is induced by elevated temperature, as well as estrogen in hormone responsive cells. This protein is involved in stress resistance and actin organization. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSP's and mammalian a-crystalline lens protein. Because of the estrogen responsive nature of Hsp27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. This work has led to the suggestion that Hsp27 may be a useful marker in classifying various hormone sensitive tumors.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI28-738)
Fournisseur:
ProSci Inc.
Description:
ZNF265 is a protein that has been shown to bind to the spliceosomal components U1-70K and U2AF35 and to direct alternative splicing. Analysis of the structure reveals substantial similarity to known RNA-binding motifs in terms of the distribution of key surface residues responsible for making RNA contacts, despite a complete lack of structural homology. An RNA gel shift assay was used to demonstrate that a single crossed finger domain from ZNF265 is capable of binding to an RNA message. Taken together, these results define a new RNA-binding motif and should provide insight into the functions of the >100 uncharacterized proteins in the sequence data bases that contain this domain.
UOM:
1 * 1 EA
Fournisseur:
Thermo Scientific
Description:
Les incubateurs à CO₂ HERAcell® i fournissent des conditions de croissance stables et précises qui offrent une excellente protection contre la contamination des cultures précieuses de cellules et de tissus. Les temps de récupération de CO₂ et de température extrêmement courts améliorent la croissance cellulaire – Disponibles en deux tailles pratiques et deux conceptions de chambre intérieure ; acier inoxydable non corrosif et cuivre massif 100% antimicrobien (pour prévenir la prolifération naturelle des bactéries et des champignons). Les modèles standard sont fournis avec des capteurs de conductivité thermique (TC) de haute qualité.
Numéro de catalogue:
(PRSI33-413)
Fournisseur:
ProSci Inc.
Description:
Recognises a protein of 75 kDa, identified as gamma heavy chain of human immunoglobulins. Its epitope maps in CH2 domain of Fc region of IgG. It reacts with all sub-classes of gamma chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(620-2693)
Fournisseur:
TESTO
Description:
We spend a large part of our time indoors – in our homes, workplaces or public buildings. A bad indoor air quality can trigger certain health problems ; mold and fungi growth can cause allergies and asthma ; high CO₂ concentrations can cause headaches and concentration problems. Regular measurement of indoor air quality and comfort levels in workplaces enables the exact setting of the indoor climate and reduces the risk of staff shortages due to illness. Indoor air quality and comfort level measurement therefore also leads to fostering better staff performance.
UOM:
1 * 1 ST
Numéro de catalogue:
(28-9180-11)
Fournisseur:
Cytiva
Description:
Les colonnes PD MidiTrap G-10 sont des colonnes gravitaires préemballées à usage unique pour l'échange de tampon et le nettoyage d'échantillons biologiques, par exemple de peptides, de petites protéines et d'oligosaccharides.
UOM:
1 * 50 ST
Fournisseur:
HARVARD APPARATUS LTD
Description:
The Pump 11 Elite series sets a new standard for handling the challenges of new applications. It has served the research community as the work horse infusion pump for micro and macro fluidic applications including MS calibration, reactor dosing, animal drug/nutritional studies, cell injections, electrospinning and more.
Fournisseur:
Heidolph Instruments GmbH & Co.KG
Description:
<B>Têtes de pompe SP standard 1,6 mm et SP standard 2,5 mm:</B> Pour usages de routine. Boîtier en aluminium moulé sous pression.. Rouleaux en acier inoxydable, roulements en polyamide.. Rotor équipé de deux 2 rouleaux convexes ; empêchant les cultures cellulaires d'être endommagées.. Pour les tubes dont l'épaisseur de paroi est de 1,6 ou 2,5 mm. Débit nominal : 0,5 à 3644 ml/min (en fonction du mécanisme d'entraînement et des tubes utilisés).
Fournisseur:
Thermo Fisher Scientific
Description:
Étanchéité efficace de tous les formats de microplaque. Pour le stockage, la PCR, la microscopie, la culture et la protection.
Numéro de catalogue:
(PROOVHG-OSF-PB1000)
Fournisseur:
LGC Standards PROMOCHEM
Description:
This solution is intended for use as a certified reference material or calibration standard for the analysis of this element in petroleum products or other organic matrices using x-ray fluorescence (XRF) spectrometry, inductively coupled plasma optical emission spectroscopy (ICPOES), inductively coupled plasma mass spectrometry (ICP-MS), rotating disc electrode atomic emission spectroscopy (RDE-AES), flame or furnace atomic absorption spectroscopy (AA or GFAA), and other techniques for elemental analysis.
UOM:
1 * 50 g
Fournisseur:
iST Scientific Ltd
Description:
Film perforable transparent idéal pour plaques en PP, PE, PS et COC. Adapté au séquenceur ABI 3730, car sa structure plus fine perce plus facilement.
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