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Numéro de catalogue: (BOSSBS-1805R-A647)

Fournisseur:  Bioss
Description:   Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
UOM:  1 * 100 µl
Numéro de catalogue: (116547050.)

Fournisseur:  MP Biomedicals
Description:   The SPINeasy® DNA Pro Kit for Feces is able to handle a wide range of fecal samples.
UOM:  1 * 1 KIT
New Product
Numéro de catalogue: (M1386-01)

Fournisseur:  OMEGA BIO-TEK
Description:   Le kit Mag-Bind® RXNPure Plus permet de procéder à une isolation rapide et fiable d'ADN par PCR et réactions enzymatiques avec des taux de récupération élevés. Ce système associe les chimies exclusives aux propriétés de liaison réversibles de l'acide nucléique de billes magnétiques liant de façon sélective les amplicons PCR de 100 pb et plus et éliminent les excès de nucléotides, d'amorces et les petits produits d'amplification non ciblés, tels que les dimères-amorces.
UOM:  1 * 50 mL
Fournisseur:  Merck
Description:   N-Méthyl-N-(triméthylsilyl)trifluoroacetamide pour la chromatographie en phase gazeuse, Supelco®
UOM:  1 * 5 mL

Fournisseur:  Bioss
Description:   The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].
UOM:  1 * 100 µl
Fournisseur:  MACHEREY-NAGEL
Description:   NucleoSpin® RNA mini spin kit for the isolation of RNA of the highest integrity.
Numéro de catalogue: (BOSSBS-1686R-CY7)

Fournisseur:  Bioss
Description:   Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1686R-CY3)

Fournisseur:  Bioss
Description:   Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication.
UOM:  1 * 100 µl
Fournisseur:  Roth Carl
Description:   Media with high quality standards.
Numéro de catalogue: (BOSSBS-2969R-CY5.5)

Fournisseur:  Bioss
Description:   E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-5981R-CY5)

Fournisseur:  Bioss
Description:   p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-4184R)

Fournisseur:  Bioss
Description:   p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
UOM:  1 * 100 µl
Numéro de catalogue: (4M15303)

Fournisseur:  Avantor
Description:   Avantor® Apex HPLC column phases are recommended for routine analyses.
UOM:  1 * 1 ST

Fournisseur:  Bioss
Description:   The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008].
UOM:  1 * 100 µl

Fournisseur:  MP Biomedicals
Description:   Quick and convenient purification of total RNA from animal tissues, plant tissues and tissue cultures using spin column technology.
UOM:  1 * 50 Tests
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