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Numéro de catalogue:
(BOSSBS-7689R-CY5)
Fournisseur:
Bioss
Description:
Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7689R-CY7)
Fournisseur:
Bioss
Description:
Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7689R-CY3)
Fournisseur:
Bioss
Description:
Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7689R-CY5.5)
Fournisseur:
Bioss
Description:
Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM:
1 * 100 µl
Numéro de catalogue:
(EBRO1340-6658)
Fournisseur:
EBRO
Description:
L'enregistreur de données de température EBI 12-T237 est idéal pour les contrôles de routine polyvalents dans les industries alimentaire et pharmaceutique. alimentaire et pharmaceutique.
Avec une plage de mesure étendue, un capteur PT1000 de haute qualité, un indice de protection IP 68 et la possibilité d'utilisation en autoclave, il assure un contrôle fiable de la pasteurisation et de la sécurité alimentaire.
UOM:
1 * 1 ST
Fournisseur:
ELTEN GMBH
Description:
La semelle intérieure semi-orthopédique offre un amorti individuel et une distribution du poids qui soulagent la douleur et les points de pression.
Fournisseur:
HERENZ HEINZ
Description:
Les Steristoppers® d'origine ont fait leurs preuves en offrant une excellente étanchéité pour les échantillons microbiologiques et les cultures de tissus dans des tubes à essai et Erlenmeyers. Ils sont utilisés en permanence dans certains des plus célèbres laboratoires de microbiologie au monde.
Numéro de catalogue:
(734-2152)
Fournisseur:
Thermo Fisher Scientific
Description:
These caps reduce the need for open interventions and support the use of aseptic methods for fluid handing relating to filling, inoculation, feeding and harvesting of the cell factory system.
UOM:
1 * 100 ST
Numéro de catalogue:
(NEOL7-8040)
Fournisseur:
NEOLAB
Description:
Boxes are made of polypropylene for the storage of light-sensitive samples. 100 places 12,5×12,5 mm for 0,5, 1,5, 2,0 ml microcentrifuge and cryo tubes.
UOM:
1 * 5 ST
Fournisseur:
JULABO GmbH
Description:
Les circulateurs à montage sur support de la série MAGIO™ fonctionnent avec une plage de température de travail de −50 à +300 °C* et une capacité de chauffage allant jusqu'à 3 kW. Grâce à leur puissante pompe de pression/aspiration, les appareils MAGIO™ sont idéaux pour les applications à température externe. Grâce à une gamme étendue d'accessoires et à une excellente dynamique, les thermostats à immersion MAGIO™ peuvent être adaptés à différents réservoirs et applications.
Fournisseur:
HAMILTON BONADUZ
Description:
Thanks to a soft contoured handle and a curved hilt these pipettes rest comfortable in your hand. The slim ejection sleeve is made from a high strength, chemically resistant polymer. The slim design allows the pipette to reach to the bottom of narrow tubes without the need for extended length tips.
Fournisseur:
Restek
Description:
These preventive maintenance (PM) kits are suitable for Waters HPLC and ACQUITY UPLC Systems.
Numéro de catalogue:
(BOSSBS-3964R-CY7)
Fournisseur:
Bioss
Description:
PKA (or cAPK) is a cyclic AMP dependent protein kinase. When activated by the second messenger cAMP, PKA mediates diverse cellular mechanisms, including proliferation, ion transport, regulation of metabolism, plus gene transcription. PKA is comprised of two dimers of two subunits, R (regulatory) and C (catalytic). Two families of R subunit (RI and RII) and three C subunit isoforms (C alpha, C beta, and C gamma) have been identified each possessing distinct cAMP binding properties and resulting in different phosphorylation states. C subunit is activated through autophosphorylation and direct phosphorylation at Thr197 by PDK-1. Tissue specific expression of C gamma, indicates pressure on C gamma during evolution, acting to modulate it in a functionally specific way. Certain amino acid substitutions make C gamma a distinct member of the cAMP dependent subfamily of protein kinases, and suggest that C gamma may be distinct in its protein substrate specificity or its interaction with the different regulatory subunits.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7685R-A647)
Fournisseur:
Bioss
Description:
Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.
UOM:
1 * 100 µl
Fournisseur:
BURKLE
Description:
LDPE, translucide, embout de pulvérisation PP, tuyau PE, poids en acier inoxydable.
Fournisseur:
EPPENDORF
Description:
Eppendorf® Safe-Lock tubes 0,5 ml - Microtube ensures secure sample storage. With a unique locking mechanism, these tubes prevent accidental opening, safeguarding precious samples. Ideal for PCR, these tubes offer reliability and ease in a compact design.
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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