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Fournisseur:  IMMUNOLOGIC
Description:   Bright Diluent is provided as a ready to use normal antibody diluent intended for diluting and stabilising antibodies. It eliminates background encountered in immunohistochemistry staining procedures. The diluent contains complex proteins and non-protein mixtures which eliminates immunohistostaining background by blocking Fc receptors and prevents non-specific protein-protein interactions.
Numéro de catalogue: (732-3879)

Fournisseur:  Genscript
Description:   eZwest™ Lite is an automated western blotting device providing an easy and simple solution in your western blotting workflow. After proteins are transferred onto the membrane, load the membrane into our eZwest™ Lite device for automated blocking, incubation, and washing cycles. The user only needs to prepare the required reagents, run the customised program, and eZwest™ Lite will take care of the rest. Once the program is finished, the user can collect the results and immediately proceed to detection and analysis steps. eZwest™ Lite is easy to use and has minimal footprint.
UOM:  1 * 1 SET

Fournisseur:  ProSci Inc.
Description:   The HTA125 monoclonal antibody specifically reacts with human CD284, a 110 kDa type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4). CD284 is an important molecule in the innate immunity response to bacterial lipoproteins. It is expressed by monocytes, macrophages, and endothelial cells. The HTA125 antibody can block Lipopolysaccharide-induced cytokine production and immunoprecipitate human TLR4.
UOM:  1 * 5 mg
New Product
Numéro de catalogue: (PRSI79-799)

Fournisseur:  ProSci Inc.
Description:   Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.
UOM:  1 * 1 EA
Fournisseur:  ProSci Inc.
Description:   The RM2-5 monoclonal antibody specifically binds to mouse CD2, a member of the Ig superfamily and type I transmembrane glycoprotein. CD2 is expressed on B cells, T cells, NK cells, and thymocytes and its ligand is CD48. It may be involved in immunoregulation, thymocyte maturation, and T-cell activation. The RM2-5 antibody has been reported to block CD2 mediated cell to cell adhesion.
UOM:  1 * 0,1 mg
New Product
Numéro de catalogue: (761-0015)

Fournisseur:  Binhold, Paul Lehrmittel
Description:   Coloured units representing phosphoric acids, purines and pyrimidines, for constructing DNA, t-RNA and RNA helices.
UOM:  1 * 1 ST
Source d'approvisionnement du marché Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Numéro de catalogue: (STMC100-0671)

Fournisseur:  STEMCELL Technologies
Description:   The EBV (LMP2) Peptide pool is a lyophilised mixture of 122 peptides from latent membrane protein 2 (LMP2) of Epstein-Barr virus (EBV; strain B95-8). LMP2 is expressed in EBV latency, as well as in EBV-associated pathologies and it blocks reactivation of EBV from latency. The pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 497 on LMP2.
UOM:  1 * 1 Kit
Source d'approvisionnement du marché Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Numéro de catalogue: (PRSI51-132)

Fournisseur:  ProSci Inc.
Description:   Reacts with CD95 (Fas/APO-1), a 46 kDa single chain type I glycoprotein of the tumour necrosis factor/nerve growth factor (TNF/NGF) receptor superfamily, expressed on a variety of normal and neoplastic cells. It seems that the antibody LT95 does not induce Fas mediated apoptosis, although it cross-blocks anti-Fas DX2 antibody that recognizes a functional epitope of Fas molecule.
UOM:  1 * 50 µG
Fournisseur:  ProSci Inc.
Description:   The H35-17.2 monoclonal antibody specifically reacts the mouse cd8 beta, a 32 kDa chain also known as Ly-3 and Lyt-3. CD8 is a T cell surface antigen co-receptor that interacts with MHC class I molecules on antigen presenting cells. It is expressed as a heterodimer with the alpha cd8 chain. The H35-17.2 antibody blocks T cell-mediated cytolysis of allogeneic lymphoma cells.
UOM:  1 * 0,05 mg
New Product

Fournisseur:  ProSci Inc.
Description:   The RM134L monoclonal antibody specifically reacts with mouse CD252, a TNF/NGF superfamily member present on activated B lymphocytes and antigen-presenting cells. On activated B cells it enhances immunoglobulin secretion and cell proliferation. CD252 is also known as the OX-40 ligand and interacts with the OX-40 antigen found on the surface of activated T cells. The RML134L is reported to block the costimulatory activity of OX-40L.
UOM:  1 * 0,025 mg
New Product
Fournisseur:  ProSci Inc.
Description:   The RM134L monoclonal antibody specifically reacts with mouse CD252, a TNF/NGF superfamily member present on activated B lymphocytes and antigen-presenting cells. On activated B cells it enhances immunoglobulin secretion and cell proliferation. CD252 is also known as the OX-40 ligand and interacts with the OX-40 antigen found on the surface of activated T cells. The RML134L is reported to block the costimulatory activity of OX-40L.
UOM:  1 * 0,025 mg
New Product
Numéro de catalogue: (PRSI33-211)

Fournisseur:  ProSci Inc.
Description:   TGF alpha is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype. This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. Staining with the antibody is completely blocked by the peptide used for raising this antibody.
UOM:  1 * 1 EA
New Product

Fournisseur:  ProSci Inc.
Description:   The HMb1-1 monoclonal antibody specifically reacts with mouse/rat CD29, a 130 kDa molecule also known as integrin beta 1, GPIIa, and the VLA-beta chain. It is expressed broadly on endothelial cells, epithelial, leukocytes, and smooth muscle. CD29 forms the VLA 1-6 complexes through the non-covalent interaction with the alpha integrins of CD49 a-f. The HMb1-1 antibody is capable of inhibiting T cell proliferation and blocking cell adhesion.
UOM:  1 * 0,05 mg
New Product
Fournisseur:  ProSci Inc.
Description:   The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains gamma, delta, and epsilon subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 epsilon chain.
UOM:  1 * 0,1 mg
New Product

Fournisseur:  ProSci Inc.
Description:   The HM40-3 monoclonal antibody reacts with mouse CD40, a 48 kDa type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.
UOM:  1 * 0,1 mg
New Product
Numéro de catalogue: (PRSI91-619)

Fournisseur:  ProSci Inc.
Description:   PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational modification. Farnesylation is required for membrane targeting and for interaction with RABGGTB. The unfarnesylated forms are redirected to the nucleus and cytosol. It can stimulate progression from G1 into S phase during mitosis and promotes tumors. It also inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB.
UOM:  1 * 50 µG
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