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Numéro de catalogue: (STMC100-0170)

Fournisseur:  STEMCELL Technologies
Description:   For expansion and differentiation of hPSCs to NK cells.
UOM:  1 * 1 Kit
Source d'approvisionnement du marché Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.

Fournisseur:  HyClone products (Cytiva)
Description:   Balanced salt solution for cell culture applications.
UOM:  1 * 500 mL
Fournisseur:  MP Biomedicals
Description:   Used to minimise cell attachment or aggregation.
UOM:  1 * 500 mL
Numéro de catalogue: (444-0274)

Fournisseur:  VWR Collection
Description:   Mini-agitateur d’incubation avec commande par microprocesseur, idéal les suspensions bactériennes, les hybridations, la coloration et la décoloration, les études de métabolisme et les cultures cellulaires. La commande à vitesse variable assure une agitation constante et uniforme. La vitesse est ajustable par incréments de 10 tr/min jusqu’à 500 tr/min et par incréments de 25 tr/min jusqu’à 1200 tr/min, et la fonction d’accélération progressive permet d’augmenter progressivement la vitesse jusqu’à un point déterminé pour plus de sécurité. La plateforme peut accueillir jusqu’à 5×250 ml Erlenmeyers ou récipients d’une hauteur maximale de 130 mm.
UOM:  1 * 1 ST
Environmentally Preferable
Numéro de catalogue: (STMC100-0715)

Fournisseur:  STEMCELL Technologies
Description:   Serum-free and animal component-free supplement for expansion of NK cells.
UOM:  1 * 5 mL
Source d'approvisionnement du marché Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Fournisseur:  Corning
Description:   Sodium bicarbonate is used as part of a buffering system commonly used to maintain physiological pH 7,2 to 7,4 in a culture environment
Numéro de catalogue: (25-060-CI)

Fournisseur:  Corning
Description:   HEPES (N-2-hydroxyethylpiperazine-N'-2-ethanesulphonic acid) provides an alternative to the use of bicarbonate for buffering because it does not require elevated levels of CO2
UOM:  1 * 6 ST
Numéro de catalogue: (BOSSBS-2035R-CY3)

Fournisseur:  Bioss
Description:   Required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet-activating factor (PAF) by removing the acetyl group at the SN-2 position (By similarity). Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates. During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules. May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0251R-A488)

Fournisseur:  Bioss
Description:   Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5. Mediates retinoic acid-induced granulopoiesis. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0251R-A555)

Fournisseur:  Bioss
Description:   Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5. Mediates retinoic acid-induced granulopoiesis. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
UOM:  1 * 100 µl
Numéro de catalogue: (215-1844)

Fournisseur:  schuett-biotec GmbH
Description:   Clear glass.
UOM:  1 * 10 ST

Fournisseur:  Bioss
Description:   Required for organisation of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organisation at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Plays a role, together with DISC1, in the regulation of neurite outgrowth. Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1. Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Required for organisation of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organisation at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Plays a role, together with DISC1, in the regulation of neurite outgrowth. Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1. Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL.
UOM:  1 * 100 µl
Fournisseur:  Thermo Fisher Scientific
Description:   Experience optimal performance with Thermo Scientific Nunc EasYFlask flasks with Nunclon Supra surface treatment for culturing a wide variety of fastidious adherent cells. The ergonomic design with angled neck and wide opening allows easy access to the growth surface by pipettes or cell scrapers. Intended for general cell culture applications, the Nunclon Supra surface is more hydrophilic than the Nunclon Delta surface, enhancing the growth of finicky cell types under no-serum or low-serum conditions.
Environmentally Preferable
New Product
Numéro de catalogue: (STMC06070)

Fournisseur:  STEMCELL Technologies
Description:   For culture of human, mouse, and rat epithelial stem cells.
UOM:  1 * 500 mL
Source d'approvisionnement du marché Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.

Fournisseur:  Bioss
Description:   Kallikrein 9, also known as Kallikrein-Like 3 (KLK-L3), is a chymotrypsin-like serine proteinase. Kallikrein 9 was discovered as the locus for kallikreins on chromosome 19 was more fully mapped and found by similarity to the other tissue kallikreins. Kallikrein 9 has been found in the ovary, thymus, testis, prostate, skin, breast and neuronal tissues and is made by many cell lines in culture. Kallikrein 9 levels in breast cancer and uterine cancer patients have been reported to drop as the disease progresses, thus hK9 might be considered a favorable prognostic marker. Different splice variants of hK9 have been reported, although it is not yet known if they produce functional proteins. The full length Kallikrein 9 encodes for a 250 amino acid protein, with a predicted mass of 27.5 kDa and a pI of 7.53. The 234 amino acid form predicts a protein of 26 kDa with a pI of 9.76 and this quite basic pI might give the shorter form a very different function or localization. The shorter sequence also diverges before the catalytic serine residue, making it unlikely to be proteolytically active. Pre-pro-kallikrein 9 has the 17 amino acid signal sequence is removed before secretion, and the Pro-kallikrein 9 is activated to Kallikrein 9 by removal of the 5 amino acid propeptide domain.
UOM:  1 * 100 µl
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