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Fournisseur:  ProSci Inc.
Description:   Adipophilin, also called Perilipin 2, ADRP (Adipose differentiation related protein), and PLIN2, belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material and maybe involved in development and maintenance of adipose tissue. It is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.
UOM:  1 * 1 EA
New Product

Fournisseur:  ProSci Inc.
Description:   Adipophilin, also called Perilipin 2, ADRP (Adipose differentiation related protein), and PLIN2, belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material and maybe involved in development and maintenance of adipose tissue. It is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (PRSI38-211)

Fournisseur:  ProSci Inc.
Description:   Epidermal growth factor (EGF) has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide. EGF exerts its actions by binding to the EGFR, a 170 kDa protein. Epidermal growth factor is also a key growth factor regulating cell survival. Through its binding to cell surface receptors, EGF activates an extensive network of signal transduction pathways that include activation of the PI3K/AKT, RAS/ERK and JAK/STAT pathways
UOM:  1 * 50 µG
Numéro de catalogue: (PRSIXP-5265BT)

Fournisseur:  ProSci Inc.
Description:   Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of mast cells and is able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. It also mediates cell to cell adhesion and acts synergistically with other cytokines, probably interleukins. A soluble form is produced by proteolytic processing of isoform 1 in the extracellular domain.
UOM:  1 * 50 µG
Fournisseur:  BTX
Description:   Sterile multi-well electroporation plates for transfection/transformation of bacteria, yeast, insect, plant and mammalian cells.
Fournisseur:  ProSci Inc.
Description:   The PK136 monoclonal antibody is specific for the mouse NK1.1, a receptor from the killer cell lectin-like receptor (KLR) family. Nk1.1 is an antigen encoded by the Klrb1c/NKR-P1C gene expressed by the natural killer cells of some selected strains of mice (C57BL, FVB/N, NZB) and encoded by the Klrb1b/NKR-P1B gene expressed on Swiss NIH and SJL mice. Pk136 binds to an epitope common to NKR-P1B and NKR-P1C.The Klrb1 is a family of type II transmembrane C-type lectin receptors. Klrb1c activates the NK-cell cytotoxicity, while Klrb1b inhibits it. PK136 is useful in defining the NK cells and the rare population of NK-T lymphocytes and specific cultured monocytes.
UOM:  1 * 0,1 mg
New Product
Fournisseur:  ProSci Inc.
Description:   The H57-597 monoclonal antibody is specific for the beta chain of the mouse T cell Receptor (TCR). The crosslinking induces activation and proliferation of T cells, as a plate-bound or a soluble H57-597, or the plate-bound antibody can induce apoptosis, based on assay conditions. The beta chain of the TCR can combine with the alpha chain of the receptor to produce the alpha-beta TCR, which is expressed by the NKT cells, by the NK1.1+ thymocytes and most of the T cells. The beta chain does not react with the gamma-delta TCR-bearing cells, expressed by a small number of T cells. This antibody can be used as a phenotypic marker for the TCR beta expressing cells or for the functional purpose of TCR-mediated cell activation or apoptosis.
UOM:  1 * 0,025 mg
New Product
Numéro de catalogue: (OHAU30391989)

Fournisseur:  OHAUS
Description:   This digital rocking shaker is ideal for cell culture work and is designed to be used in a variety of environmental conditions. The cast aluminium base offers durability and added stability.
UOM:  1 * 1 ST
Numéro de catalogue: (ICNA0215572325)

Fournisseur:  MP Biomedicals
Description:   (±)-3-Mercapto-1,2-propanediol (α-Monothioglycerol) is a reagent that is used in analytical chemistry, material science, and cell culture research.
UOM:  1 * 25 mL
Fournisseur:  STEMCELL Technologies
Description:   Thrombopoietin (TPO) is a key regulator of megakaryocytopoiesis and thrombopoiesis <i>in vitro</i> and <i>in vivo</i>. TPO stimulates the proliferation and maturation of megakaryocytes and has an important role in regulating the level of circulating platelets in vivo (Bartley <i>et al.</i>; de Sauvage <i>et al.</i>; Foster <i>et al.</i>; Sohma <i>et al.</i>). TPO also promotes the survival, self-renewal, and expansion of hematopoietic stem cells and primitive multilineage progenitor cells. It is commonly used with other cytokines such as stem cell factor (SCF) and Flt3/Flk-2 ligand to promote expansion of primitive hematopoietic cells in culture (Hitchcock and Kaushansky). The TPO receptor, c-Mpl, is expressed at all stages of megakaryopoiesis, from hematopoietic stem and progenitor cells to mature platelets (Ng <i>et al.</i>).
Fournisseur:  OZ BIOSCIENCES
Description:   si3D-FectIN™ is a 3D transfection reagent specifically designed and developed for silencing gene expression in cells cultured in gels (or hydrogels).
Fournisseur:  Thermo Fisher Scientific
Description:   The glycoprotein isolation kit allows isolation of glycoproteins from complex mixtures, including serum, tissue and cultured cell lysates. The procedure uses concanavilin A (ConA) or wheat germ agglutinin (WGA) as a ligand to bind a specific class of glycoprotein from complex protein samples - those containing alpha-lined mannose or terminal glucose residues (in case of ConA) and N-Acetyl glucosamine (GlcNAc) groups or sialic acid (in case of WGA). This kit has been used to isolate glycoproteins from serum as well as HeLa and CHO cell lysates in approximately 50 minutes.
Fournisseur:  Cytiva
Description:   His Mag Sepharose® excel est un milieu de chromatographie d'affinité pour ions métalliques immobilisés (IMAC) magnétique pré-chargé avec des ions nickel qui sont fortement liés à un ligand chélatant. Le milieu permet une capture à petite échelle, une purification et un criblage reproductible des protéines marquées à l'histidine exprimées et sécrétées dans les surnageants de cultures cellulaires de cellules eucaryotes telles que les cellules d'insectes ou les cellules d'ovaire de hamster chinois (CHO, Chinese Hamster Ovary).
Fournisseur:  STEMCELL Technologies
Description:   Noggin binds to and antagonizes bone morphogenetic protein (BMP) ligands of the transforming growth factor beta (TGF-β) family. Noggin supports maintenance of undifferentiated human embryonic stem cells cultured in mouse embryonic fibroblast (MEF)-conditioned medium (Chaturvedi <i>et al.</i>), and promotes dopaminergic differentiation of embryonic stem cells and subsequent survival of dopamine neurons (Chiba <i>et al.</i>). Noggin is essential for development of ectodermal structures including neural tube, tooth, hair follicle, and eye, as well as patterning of mesodermal somites and skeletal structures. It also influences chondrogenesis, osteogenesis, and joint formation (Krause <i>et al.</i>).
Fournisseur:  ProSci Inc.
Description:   The PK136 monoclonal antibody is specific for the MouseNK1.1, a receptor from the killer cell lectin-like receptor (KLR) family. Nk1.1 is an antigen encoded by the Klrb1c/NKR-P1C gene expressed by the natural killer cells of some selected strains of mice (C57BL, FVB/N, NZB) and encoded by the Klrb1b/NKR-P1B gene expressed on Swiss NIH and SJL mice. Pk136 binds to an epitoPEcommon to NKR-P1B and NKR-P1C.The Klrb1 is a family of tyPEII transmembrane C-tyPElectin receptors. Klrb1c activates the NK-cell cytotoxicity, while Klrb1b inhibits it. PK136 is useful in defining the NK cells and the rare population of NK-T lymphocytes and specific cultured monocytes.
UOM:  1 * 0,025 mg
New Product
Fournisseur:  Greiner Bio-One
Description:   Manufactured from high quality polypropylene, Cryo.s freezing tubes are suitable for storage of cell cultures, tissue samples, microbiological samples, material of human or animal origin such as blood, serum, and sperm, as well as antibodies, RNA, DNA, and protein samples.
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