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cell+culture+plates
Numéro de catalogue:
(PRSI28-760)
Fournisseur:
ProSci Inc.
Description:
Lmx1a acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. It is required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5365)
Fournisseur:
ProSci Inc.
Description:
JMJD1A Antibody: The jumonji domain containing 1A protein (JMJD1A) was originally discovered as a testes specific gene, but has been found to be expressed in numerous tissues. JMJD1A is a histone demethylase and specifically demethylates mono- and dimethyl-H3K9. It has also been found to be a novel interaction partner with ER71, a transcription factor expressed in the testes of adult mice and during embryogenesis. JMJD1A is also a downstream gene of STAT3, a protein that has been found to be important in the maintenance of mouse embryonic stem (mES) cells, and decreased JMJD1A expression correlated with the differentiation of cultured mES cells following the removal of the cytokine LIF. These findings suggest that JMJD1A might be a critical signaling molecule underlying the maintenance of pluripotency in embryonic stem cells. At least two isoforms of JMJD1A are known to exist.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI6121)
Fournisseur:
ProSci Inc.
Description:
ZBTB4 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. Similar to Kaiso, a zinc-finger containing protein that can bind methylated CpGs, ZBTB4 can also bind methylated DNA and repress transcription. ZBTB4 has been shown to associate with the Sin3/histone deacetylase co-repressor and repress expression of P21CIP1 as part of a heterodimeric complex with Miz1. In cultured cells, depletion of ZBTB4 promotes cell cycle arrest in response to p53 activation and suppresses apoptosis through regulation of P21CIP1, suggesting that ZBTB4 is a critical determinant of the cellular response to p53 activation. HIPK2, a kinase that is involved in cellular proliferation and survival, phosphorylates and down-regulates ZBTB4 under normal cell growth conditions; this degradation increases with DNA damage.
UOM:
1 * 1 EA
Numéro de catalogue:
(786-411)
Fournisseur:
G-Biosciences
Description:
Insect PE LB™ has been developed for extraction of total biologically active, soluble proteins from adherent or suspension cultured insect cells, including Sf9 and Sf21. Insect PE LB™ utilises a mild non-ionic detergent and a proprietary combination of various salts and agents to enhance extraction and stability of proteins. The Insect PE LB™ is fully compatible with downstream processes, such as electrophoresis and chromatography. Depending on the required downstream application, additional agents such as reducing agents and protease inhibitors may be added into Insect PE LB™.
UOM:
1 * 250 mL
Numéro de catalogue:
(SPCMSO193-500GM)
Fournisseur:
Spectrum Chemical
Description:
Sodium Pyruvate, Reagent is most often added to the cell culture media as an extra source of energy. Sodium pyruvate also has a protective action against hydrogen peroxide. The Reagent grade denotes that this chemical is the highest quality commercially available and that the American Chemical Society has not officially set any specifications for this material. Spectrum Chemical manufactured Reagent grade products meet the toughest regulatory standards for quality and purity.
UOM:
1 * 500 g
Fournisseur:
VWR Collection
Description:
SAS Super est un système complet pour le prélèvement microbiologique de l'air: les instruments assurent un échantillonnage actif de l'air sur une ou deux boîtes de milieu de culture pré-coulées. Quand la contamination de l'environnement est très basse et que le nombre d'échantillons à traiter est élevé, la durée des opérations peut constituer un facteur majeur dans le choix d'un instrument SAS. Grâce à deux têtes d'échantillonnage pouvant fonctionner simultanément, DUO SAS 360 est la bonne solution pour échantillonner 1 000 l d'air en moins de 3 minutes. L'échantillonnage simultané sur deux têtes permet d'obtenir des résultats statistiques représentatifs lorsque le même type de milieu est utilisé sur les 2 têtes. Il est également possible d'utiliser deux milieux différents pour le même cycle d'échantillonnage (par exemple: flore totale et levures - moisissures). L'échantillonnage simultané sur deux têtes peut réduire de moitié la durée du processus d'échantillonnage.
Fournisseur:
STEMCELL Technologies
Description:
Stem cell factor (SCF) is an early-acting cytokine that plays a pivotal role in the regulation of embryonic and adult hematopoiesis. SCF promotes cell survival, proliferation, differentiation, adhesion, and functional activation of cells at multiple levels of the hematopoietic hierarchy. Together with other cytokines such as thrombopoietin and Flt3/Flk-2 Ligand, SCF is commonly used to promote expansion of primitive hematopoietic stem cells and multi-potent progenitor cells in culture (Martin <i>et al.</i>; Kent <i>et al.</i>). In synergy with various growth factors, including IL-2, IL-3, IL-6, IL-7, G-CSF, and erythropoietin, SCF increases proliferation and differentiation of myeloid and erythroid progenitor cells and a subset of lymphoid progenitor cells (Broudy). SCF is also a primary growth and activation factor for mast cells and eosinophils. SCF exists in two biologically active splice forms: a soluble and a transmembrane isoform. Upon binding to its receptor (c-Kit tyrosine kinase receptor; CD117), it activates PI3K, JAK/STAT, and MAPK pathways. SCF and signaling from c-Kit have also been reported to play an important role in pigmentation, fertility, vasculogenesis, motility of the gut via c-Kit positive interstitial cells of Cajal, and in the migration of neuronal stem and progenitor cells to sites of injury in the brain.
Numéro de catalogue:
(PRSI96-652)
Fournisseur:
ProSci Inc.
Description:
Tyrosine-protein kinase transmembrane receptor ROR2 is also known as Neurotrophic tyrosine kinase, receptor-related 2 (NTRKR2), which belongs to the protein kinase superfamily and Tyr protein kinase family and ROR subfamily. ROR2 is a homodimer protein, which can binds YWHAB or interact with WTIP. ROR2 may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI76-969)
Fournisseur:
ProSci Inc.
Description:
The ISA-3 monoclonal antibody specifically reacts with human CD278 or Inducible COStimulatory molecule (ICOS), a 47 to 60 kDa homodimeric glycoprotein also known as H4, AILIM, and CRP-1. It is expressed on activated T cells and a group of thymocytes and is involved in the proliferation, activation, and cytokine production of T cells. When plate-bound, the ISA-3 antibody induces the production of IL-4,5,10 in T cells.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI76-970)
Fournisseur:
ProSci Inc.
Description:
The ISA-3 monoclonal antibody specifically reacts with human CD278 or Inducible COStimulatory molecule (ICOS), a 47 to 60 kDa homodimeric glycoprotein also known as H4, AILIM, and CRP-1. It is expressed on activated T cells and a group of thymocytes and is involved in the proliferation, activation, and cytokine production of T cells. When plate-bound, the ISA-3 antibody induces the production of IL-4,5,10 in T cells.
UOM:
1 * 25 Tests
New Product
Fournisseur:
OZ BIOSCIENCES
Description:
CombiMag™ transfection reagent is based on the use of magnetic nanoparticles for improving transfection reagent efficiency. It has been designed to be employed in association with any commercial transfection reagent and can be used with all types of nucleic acids. It has been successfully tested on a broad range of primary cells, hard to transfect cells and cell lines.
Fournisseur:
MP Biomedicals
Description:
Synonym: N-2-Hydroxyethylpiperazine-N′-2-ethanesulfonic acid)
Cell Culture Reagent Crystalline Free Acid Zwitterionic Buffer useful in the pH range 6.8-8.2. pKa=7.55 at 25°C
Fournisseur:
STEMCELL Technologies
Description:
Betacellulin is a member of the epidermal growth factor (EGF) family, and signals through EGF receptor and ERBB4. It activates ERK and AKT pathways, which induces neural stem cell proliferation and prevents spontaneous differentiation in culture. Betacellulin stimulates the expansion of neural stem cells, transit-amplifying cells, and neuroblasts derived from subventricular zone and dentate gyrus (Gómez-Gaviro <i>et al.</i>). It is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin down-regulates E-cadherin expression in ovarian cancer cell lines via MEK/ERK1/2 and PI3K/AKT signaling pathways, thus increasing cell migration (Zhao <i>et al.</i>). It is a modulator of interferon (IFN) response and enhances anti-viral effects of IFN (Al-Yahya <i>et al.</i>). Betacellulin is expressed in pancreatic α cells, β cells, and duct cells. It induces the proliferation of pancreatic cancer cell lines, inhibits apoptosis, promotes the neogenesis of β cells, and converts non-β cells into insulin-producing cells (Kawaguchi <i>et al.</i>; Miyagawa al.; Saito <i>et al.</i>).
Fournisseur:
MP Biomedicals
Description:
Ammonium tartrate, the ammonium salt of tartaric acid, is used in such applications as cell culture and chromatography.
Fournisseur:
MP Biomedicals
Description:
Glycine is a non-essential amino acid. Acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. Shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. Also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons. It does not have a chiral center, so only amino acid with no asymmetric carbon. Therefore, it does not have a D- or L- isomer designation. This material is synthetic. It is the smallest of the 20 natural amino acids.
Fournisseur:
OZ BIOSCIENCES
Description:
Glial-Mag is designed to reach optimal transfection efficiency with microglial cell lines and primary cells. Glial-Mag kit is the association of a specific magnetic nanoparticles formulation (Glial-Mag reagent), issued from our Magnetofection™ technology and a booster (Glial-Boost) designed to enhance transfection efficiency.
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