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Protéines et Peptides
Numéro de catalogue:
(PRSI92-050)
Fournisseur:
ProSci Inc.
Description:
Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. PARVA may play a role in the regulation of cell adhesion and cytoskeleton organization. PARVA is also involved in ciliogenesis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-555)
Fournisseur:
ProSci Inc.
Description:
Vascular Non-Inflammatory Molecule 2 (VNN2) is a member of the CN hydrolase family. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. they possess pantetheinase activity, which may play a role in oxidative-stress response. VNN2 is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. VNN2 involved in the thymus homing of bone marrow cells. In addition, VNN2 may regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-118)
Fournisseur:
ProSci Inc.
Description:
Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED)-containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumourigenesis and cancer progression. PEA15 is overexpressed in breast cancers and gliomas as well as in type 2 diabetes. PEA15 blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. PEA15 also inhibits RPS6KA3 activities by holding it in the cytoplasm. In addition, PEA15 inhibits both TNFRSF6 and TNFRSF1A mediated CASP8 activity and apoptosis. At present, PEA15 expression is also a significant prognostic marker in ovarian cancer.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5309P)
Fournisseur:
ProSci Inc.
Description:
PGCC1 peptide is used for blocking the activity of PGCC1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5307P)
Fournisseur:
ProSci Inc.
Description:
FAM120A peptide is used for blocking the activity of FAM120A antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5291P)
Fournisseur:
ProSci Inc.
Description:
NOTUM peptide is used for blocking the activity of NOTUM antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-120)
Fournisseur:
ProSci Inc.
Description:
Fatty acid-binding protein 5 (FABP5) is a cytoplasm protein that belongs to the fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids. FABP5 can be expressed in keratinocytes, and is highly expressed in psoriatic skin. FABP5 has been shown to be involved in keratinocyte differentiation. FABP5 has high specificity for fatty acids, the highest affinity for C18 chain length. FABP5 can decrease the chain length or introduce double bonds to reduce the affinity.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-155)
Fournisseur:
ProSci Inc.
Description:
The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signalling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-169)
Fournisseur:
ProSci Inc.
Description:
Contactin-6 is a member of the contactins, which mediate cell surface interactions during nervous system development. Contactin-6 has a key role in the formation of glutamatergic, but not GABAergic, synapses during postnatal development of the hippocampal formation as well as the cerebellum. It is involved in oligodendrocytes generation by acting as a ligand of Notch1. It is also involved in motor coordination.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-144)
Fournisseur:
ProSci Inc.
Description:
Programmed Cell Death Protein 5 (PDCD5) is a member of the PDCD5 family. PDCD5 is expressed in tumour cells during apoptosis, independent of apoptosis-inducing stimuli. This protein may function in the process of apoptosis. PDCD5 is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. PDCD5 may play an important regulator of K (lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. PDCD5 is an important novel protein that regulates both apoptotic and non-apoptotic programmed cell death.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-371)
Fournisseur:
ProSci Inc.
Description:
Semaphorin-4A (SEMA4A) belongs to the semaphorin family which contains a Ig-like C2-type domain, a PSI domain and a Sema domain. SEMA4A is expressed from day 10 in the embryo, and low levels are found between days 10-12. SEMA4A is a cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signalling. It plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. SEMA4A promotes phosphorylation of TIMD2, inhibits angiogenesis, and promotes axon growth cone collapse, Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-958)
Fournisseur:
ProSci Inc.
Description:
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5877P)
Fournisseur:
ProSci Inc.
Description:
SESTD1 peptide is used for blocking the activity of SESTD1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5883P)
Fournisseur:
ProSci Inc.
Description:
WDR92 peptide is used for blocking the activity of WDR92 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4393P)
Fournisseur:
ProSci Inc.
Description:
Grik4 peptide is used for blocking the activity of Grik4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6847P)
Fournisseur:
ProSci Inc.
Description:
SDHD peptide is used for blocking the activity of SDHD antibody.
UOM:
1 * 50 µG
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