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Protéines et Peptides
Numéro de catalogue:
(PRSI4295P)
Fournisseur:
ProSci Inc.
Description:
DISC1 peptide is used for blocking the activity of DISC1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-708)
Fournisseur:
ProSci Inc.
Description:
T-Cell Surface Glycoprotein CD3 epsilon Chain (CD3 epsilon ) is a single-pass type I membrane protein. CD3 epsilon contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3 epsilon is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5109P)
Fournisseur:
ProSci Inc.
Description:
ATOH8 peptide is used for blocking the activity of Atoh8 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI40-601)
Fournisseur:
ProSci Inc.
Description:
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues. Recombinant human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-068)
Fournisseur:
ProSci Inc.
Description:
Tumor necrosis factor alpha (TNF alpha) is the prototypic ligand of the TNF superfamily. TNF alpha forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNF alpha is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNF alpha is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-040)
Fournisseur:
ProSci Inc.
Description:
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-038)
Fournisseur:
ProSci Inc.
Description:
Somatotropin(GH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. GH stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-380)
Fournisseur:
ProSci Inc.
Description:
CD99 Antigen-Like Protein 2 (CD99L2) belongs to the CD99 family. CD99L2 is a single-pass type I membrane protein and expressed in many tissues, with low expression in thymus. CD99L2 plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. CD99L2 and CD99 are involved in trans-endothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-381)
Fournisseur:
ProSci Inc.
Description:
Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signalling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signalling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signalling cascade.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-747)
Fournisseur:
ProSci Inc.
Description:
Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Coupleing activate of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-141)
Fournisseur:
ProSci Inc.
Description:
DNER is an activator of the Notch1 pathway. It mediates neuron-glia interaction during astrocytogenesis.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI6843P)
Fournisseur:
ProSci Inc.
Description:
THBS4 peptide is used for blocking the activity of THBS4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6833P)
Fournisseur:
ProSci Inc.
Description:
CLEC7A peptide is used for blocking the activity of CLEC7A antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-546)
Fournisseur:
ProSci Inc.
Description:
Ephrin type-A receptor 4(EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-058)
Fournisseur:
ProSci Inc.
Description:
CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-051)
Fournisseur:
ProSci Inc.
Description:
Human recombinant Bace12 (from HEK293 cells)
UOM:
1 * 1 EA
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