Protéines et Peptides
Fournisseur:
ENZO LIFE SCIENCES
Description:
Caspase-6 inhibitor
Fournisseur:
ENZO LIFE SCIENCES
Description:
HDAC Substrate (fluorogenic)
Numéro de catalogue:
(PRSI96-326)
Fournisseur:
ProSci Inc.
Description:
Folate receptor beta is also known as Folate receptor 2, FBP, FOLR2, BETA-HFR, FBP/PL-1, FR-BETA, FR-P3, and is a member of the folate receptor (FOLR) family. and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. The FOLR2 protein was originally thought to exist only in placenta, but is also detected in spleen, bone marrow, and thymus. FOLR2 is predominantly expressed in placenta, cells of the neutrophilic lineage, and some CD34+ hematopoietic progenitor cells. It is upregulated on myeloid leukemias, head and neck squamous cell carcinomas, and several nonepithelial cancers. It is also upregulated on macrophages and monocytes at chronic inflammatory sites including rheumatoid arthritis synovium and glioblastoma. FOLR2 is a marker for macrophages generated in the presence of M-CSF, but not GM-CSF. Its expression correlates with increased folate uptake ability. Folate conjugates of therapeutic drugs are a potential immunotherapy tool to target tumor-associated macrophages.
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI96-089)
Fournisseur:
ProSci Inc.
Description:
CD40 is also known as TNFRSF5, Bp50, CDW40, MGC9013, TNFRSF5 and p50, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins, and plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. CD40 contains 4 cysteine-rich repeats in the extracellular domain, and is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. The extracellular domain has the cysteinerich repeat regions, which are characteristic for many of the receptors of the TNF superfamily. Interaction of CD40 with its ligand, CD40L, leads to aggregation of CD40 molecules,which in turn interact with cytoplasmic components to initiate signaling pathways. Early studies on the CD40-CD40L system revealed its role in humoral immunity. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3), an autosomal recessive disorder characterized by an inability of B cells to undergo isotype switching, as well as an inability to mount an antibody-specific immune response, and a lack of germinal center formation.
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(ENZOADISPP902D)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Produced in <i>E. coli.</i> Human phosphorylated HSF1 is fused at the N-terminus to a His-tag.
UOM:
1 * 50 µG
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
Specifically promotes neural differentiation of human neuroblastoma cells.
Numéro de catalogue:
(ENZOALX303002M025)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Prepared from cerebrosides by a modified protocol of H.E. Carter et al.; J. Lipid Res. 2, 228 (1961).
UOM:
1 * 25 mg
New Product
Numéro de catalogue:
(ENZOALX302009M001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Bovine native Ganglioside GD1b . disodium salt (from brain)
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(ENZOALX260158M005)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Inhibitor of caspase-6, -8 and -10
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(ENZOBMLP8010005)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Substrate for ubiquitin C-terminal hydrolases (UCHs)
UOM:
1 * 5 mg
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
CaM kinase II inhibitor
Numéro de catalogue:
(ENZOADISPP240J)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Isolated from bovine eye lens.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(ENZOBMLUW96700025)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Produced in <i>E. coli</i>. Poly-SUMO-2 chains were synthesized enzymatically using SUMO-2 and purified by size exclusion chromatography to remove SUMO-2 monomer.
UOM:
1 * 25 µG
New Product
Numéro de catalogue:
(ENZOBMLUW99900050)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Produced in <i>E. coli</i>.
UOM:
1 * 50 µG
New Product
Numéro de catalogue:
(ENZOBMLUW92300500)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Produced in <i>E. coli</i>. Human pro-ISG15 is fused at the N-terminus to a His-tag.
UOM:
1 * 500 µG
New Product
Numéro de catalogue:
(ENZOBMLUW99800050)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Produced in <i>E. coli</i>.
UOM:
1 * 50 µG
New Product
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