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Bioss
Numéro de catalogue:
(BOSSBS-9080R-A750)
Fournisseur:
Bioss
Description:
Casein kinases are operationally defined by their preferential utilisation of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3142R-CY5)
Fournisseur:
Bioss
Description:
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12054R-CY5)
Fournisseur:
Bioss
Description:
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5305R-A555)
Fournisseur:
Bioss
Description:
E2F's are DNA binding proteins, which associate with negative regulators, such as the retinoblastoma p107 protein, resulting in an altered rate of gene transcription. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. E2F1 is proposed to be involved in several cellular processes that range from tumor suppressor, cell progression and oncogenesis. E2F1 overexpression can also drive cells into apoptosis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12054R-CY7)
Fournisseur:
Bioss
Description:
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9027R-A350)
Fournisseur:
Bioss
Description:
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5166R-CY5.5)
Fournisseur:
Bioss
Description:
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9027R-A488)
Fournisseur:
Bioss
Description:
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9027R-A555)
Fournisseur:
Bioss
Description:
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0413R-A555)
Fournisseur:
Bioss
Description:
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2157R-A555)
Fournisseur:
Bioss
Description:
Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling (By similarity). May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate interactions.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0413R-A350)
Fournisseur:
Bioss
Description:
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5757R-FITC)
Fournisseur:
Bioss
Description:
FAM13B1
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2882R-HRP)
Fournisseur:
Bioss
Description:
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6706R-A488)
Fournisseur:
Bioss
Description:
PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5938R-A488)
Fournisseur:
Bioss
Description:
LIM domain only 3 (LMO3) belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. It is transcribed mainly in the brain. It interacts with the neuronal transcription factor, HEN2, and acts as an oncogene in neuroblastoma.
UOM:
1 * 100 µl
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