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Bioss
Numéro de catalogue:
(BOSSBS-2598R-A350)
Fournisseur:
Bioss
Description:
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10050R-HRP)
Fournisseur:
Bioss
Description:
Infectious bursal disease (IBD) is caused by infectious bursal disease virus (IBDV) an avian Birnavirus first described in the USA near the town of Gumboro Delaware and thus the disease is also known as Gumboro disease. There are 3 recognized pathogenic types of IBDV; classic virulent (cvIBDV), sub-clinical (scIBDV), and very virulent (vvIBDV). All three pathogenic types of IBDV cause immune suppression which leads to secondary infections and a failure to produce an immune response to vaccines. The cvIBDV typically cause a high morbidity and low mortality disease while the scIBDV cause very little morbidity and no mortality. The vvIBDV cause an acute disease in chickens characterized by high morbidity and high mortality.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2600R-A647)
Fournisseur:
Bioss
Description:
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10050R-FITC)
Fournisseur:
Bioss
Description:
Infectious bursal disease (IBD) is caused by infectious bursal disease virus (IBDV) an avian Birnavirus first described in the USA near the town of Gumboro Delaware and thus the disease is also known as Gumboro disease. There are 3 recognized pathogenic types of IBDV; classic virulent (cvIBDV), sub-clinical (scIBDV), and very virulent (vvIBDV). All three pathogenic types of IBDV cause immune suppression which leads to secondary infections and a failure to produce an immune response to vaccines. The cvIBDV typically cause a high morbidity and low mortality disease while the scIBDV cause very little morbidity and no mortality. The vvIBDV cause an acute disease in chickens characterized by high morbidity and high mortality.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2598R-CY3)
Fournisseur:
Bioss
Description:
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3913R-CY5.5)
Fournisseur:
Bioss
Description:
Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13483R-FITC)
Fournisseur:
Bioss
Description:
Belongs to the GOLGA6 family.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6199R-A680)
Fournisseur:
Bioss
Description:
Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0680R-CY5)
Fournisseur:
Bioss
Description:
When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0680R-CY5.5)
Fournisseur:
Bioss
Description:
When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6092R-A488)
Fournisseur:
Bioss
Description:
RHOBTB1 is a member of the Rho family of the small GTPase superfamily. Is made of a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. Plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15420R-FITC)
Fournisseur:
Bioss
Description:
HBS1L is a 684 amino acid protein that belongs to the GTP-binding elongation factor family and exists as multiple alternatively spliced isoforms. Expressed in kidney, brain, heart, placenta, liver, muscle and pancreas, HSB1L is thought to play a role in controlling fetal hemoglobin levels, specifically influencing platelet, monocyte and erythrocyte hemoglobin content. The gene encoding HBS1L maps to a locus on human chromosome 6 that is associated with sickle cell anemia and _-thalassemia, suggesting a role for HBS1L in the pathogenesis of blood disorders.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11297R-A488)
Fournisseur:
Bioss
Description:
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7613R-CY5.5)
Fournisseur:
Bioss
Description:
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.Tissue specificity: Broadly expressed, with lowest levels in brain and thymus, and highest levels detectable in heart, ovary and testis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7613R-CY3)
Fournisseur:
Bioss
Description:
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.Tissue specificity: Broadly expressed, with lowest levels in brain and thymus, and highest levels detectable in heart, ovary and testis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2644R-A750)
Fournisseur:
Bioss
Description:
Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.
UOM:
1 * 100 µl
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