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Bioss
Numéro de catalogue:
(BOSSBS-4834R-PE)
Fournisseur:
Bioss
Description:
Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4835R-CY5.5)
Fournisseur:
Bioss
Description:
Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9819R-A680)
Fournisseur:
Bioss
Description:
C2orf69.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12096R-A750)
Fournisseur:
Bioss
Description:
Peroxisomes are single-membrane bound organelles present in virtually all eukaryotic cells. They are involved in numerous catabolic and anabolic pathways, including beta-oxidation of very long chain fatty acids, metabolism of hydrogen peroxide, plasmalogen biosynthesis and bile acid synthesis. The Peroxin gene family, which includes more than 20 members, is required for peroxisome biogenesis. Peroxin 5R, also known as PEX5-related protein or Peroxisome biogenesis factor 5-like, is a 626 amino acid protein that is mainly expressed in brain, with some expression in testis and pancreas. Peroxin 5R contains five TPR repeats, which enable protein-protein interactions and assembly of large multiprotein complexes. There are three isoforms of Peroxin 5R that are produced as a result of alternative splicing events. These isoforms bind C-terminal peroxisome-targeting signals in a similar manner to Peroxin-5. Peroxin 5R interacts with Rab 8b, possibly playing a role in vesicular trafficking and neurotransmitter release.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1641R-A750)
Fournisseur:
Bioss
Description:
The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1641R-CY7)
Fournisseur:
Bioss
Description:
The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11333R-A350)
Fournisseur:
Bioss
Description:
Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with Clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of Clathrin binding Adaptin proteins (g and b1 for AP-1, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17. The a and b Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP-3 (also designated AP180 or F1-20) is a synapse-specific Clathrin assembly protein. The protein CALM (Clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in Clathrin assembly.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7720R-CY5.5)
Fournisseur:
Bioss
Description:
Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7720R-CY7)
Fournisseur:
Bioss
Description:
Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7720R-CY3)
Fournisseur:
Bioss
Description:
Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9303R-A647)
Fournisseur:
Bioss
Description:
TAL1 disruption at 1p32, a common rearrangement in the T-cell acute lymphoblastic leukemia, usually results in the formation of a SCL interrupting locus (SIL)-TAL1 fusion product. SIL is an immediate early gene whose expression is associated with cell proliferation. The Sil protein exhibits ubiquitous expression in hematopoietic cell lines and tissues. However, Sil protein levels remain tightly regulated during the cell cycle, achieving peak levels in mitosis and diminishing on transition to G1 phase. Overexpression of Sil in primary adenocarcinomas predicts metastatic spread, especially in lung tumors with increased mitotic activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9303R-CY5.5)
Fournisseur:
Bioss
Description:
TAL1 disruption at 1p32, a common rearrangement in the T-cell acute lymphoblastic leukemia, usually results in the formation of a SCL interrupting locus (SIL)-TAL1 fusion product. SIL is an immediate early gene whose expression is associated with cell proliferation. The Sil protein exhibits ubiquitous expression in hematopoietic cell lines and tissues. However, Sil protein levels remain tightly regulated during the cell cycle, achieving peak levels in mitosis and diminishing on transition to G1 phase. Overexpression of Sil in primary adenocarcinomas predicts metastatic spread, especially in lung tumors with increased mitotic activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9365R-CY5.5)
Fournisseur:
Bioss
Description:
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Necessary for activation of the CDC28 kinase.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9303R-HRP)
Fournisseur:
Bioss
Description:
TAL1 disruption at 1p32, a common rearrangement in the T-cell acute lymphoblastic leukemia, usually results in the formation of a SCL interrupting locus (SIL)-TAL1 fusion product. SIL is an immediate early gene whose expression is associated with cell proliferation. The Sil protein exhibits ubiquitous expression in hematopoietic cell lines and tissues. However, Sil protein levels remain tightly regulated during the cell cycle, achieving peak levels in mitosis and diminishing on transition to G1 phase. Overexpression of Sil in primary adenocarcinomas predicts metastatic spread, especially in lung tumors with increased mitotic activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12426R-A750)
Fournisseur:
Bioss
Description:
Casein kinases are operationally defined by their preferential utilisation of acidic proteins such as caseins as substrates. They can phosphorylate a large number of proteins. Participates in Wnt Signalling.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12428R-CY3)
Fournisseur:
Bioss
Description:
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.
UOM:
1 * 100 µl
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