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Bioss
Numéro de catalogue:
(BOSSBS-6755R)
Fournisseur:
Bioss
Description:
Tissue specificity: Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6754R)
Fournisseur:
Bioss
Description:
Enhances transcription activation by YY1.Tissue specificity:Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12083R)
Fournisseur:
Bioss
Description:
Anti-GABRQ Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15020R-HRP)
Fournisseur:
Bioss
Description:
C1orf138
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12431R-A555)
Fournisseur:
Bioss
Description:
Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1102R)
Fournisseur:
Bioss
Description:
Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10395R)
Fournisseur:
Bioss
Description:
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-1, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1065R)
Fournisseur:
Bioss
Description:
May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7062R)
Fournisseur:
Bioss
Description:
Anti-DEDD Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9538R-A350)
Fournisseur:
Bioss
Description:
Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf174 gene product has been provisionally designated C6orf174 pending further characterization.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12356R-A647)
Fournisseur:
Bioss
Description:
ALX1 is a 326 amino acid protein specific to cervix and cartilage tissues. As well as having a homeobox domain, ALX1 also contains an OAR domain, which has been suggested to be important for DNA binding or protein-protein interactions and transactivation. First characterized from a rat chondrosarcoma tumor cell line, ALX1 is a homeobox transcription factor that regulates downstream target genes and has specifically shown to act as a transcriptional repressor for rat prolactin in vivo. Homozygous ALX1 deficient mice are born with acrania and meroanencephaly, suggesting ALX1 function in the development of the neural tube. It has also been suggested that ALX1 cooperates with ALX4 in limb development and craniofacial bone formation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9480R-A488)
Fournisseur:
Bioss
Description:
May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12355R-CY3)
Fournisseur:
Bioss
Description:
Glut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity. TUG (ASPL in humans) regulates the trafficking of glucose via Glut4. Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin. TUG acts by trapping endocytosed Glut4 and tethering it intracellularly. Insulin mobilizes this pool of retained Glut4 by releasing the tether.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9481R-CY3)
Fournisseur:
Bioss
Description:
REEP5 is a 189 amino acid multi-pass membrane protein. Thought to promote the functional cell surface expression of olfactory receptors, REEP5 belongs to the DP1 family and is encoded by a gene that maps to chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12499R)
Fournisseur:
Bioss
Description:
Anti-APOL4 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11039R)
Fournisseur:
Bioss
Description:
Anti-STXBP6 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
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