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Bioss
Numéro de catalogue:
(BOSSBS-10504R)
Fournisseur:
Bioss
Description:
Anti-VARS2 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13333R)
Fournisseur:
Bioss
Description:
Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (Survival of Motor Neuron) gene. Gemin6, the protein product of human chromosome 2p22.2, associates directly with SMN and is a part of the SMN complex containing Gemin2, Gemin3, Gemin4 and Gemin5 as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13328R)
Fournisseur:
Bioss
Description:
Anti-GEMIN4 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13337R)
Fournisseur:
Bioss
Description:
Growth factor independent 1 (Gfi-1) is a transcriptional repressor that specifically binds to the DNA consensus sequence TAAATCAC(A/T)GCA. The carboxy-terminus of Gfi-1 contains six C2H2-type zinc finger motifs, and zinc fingers 3, 4 and 5 are required for the binding of Gfi-1 to its DNA binding site. Gfi-1 also contains a 20 amino acid SNAG domain which mediates transcriptional repression. It represses Bax at the mRNA and protein levels, resulting in the inhibition of cell death. Gfi1 is expressed outside the lymphoid system in granulocytes and activated macrophages. Gfi-1B, a related protein, is a transcriptional repressor primarily expressed in bone marrow and spleen. Gfi-1B is a direct repressor of the p21 promoter and the Socs 1 and 3 promoters. The genes encoding human Gfi-1 and Gfi-1B map to chromosome 1p22 and 9q34.3, respectively.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10485R)
Fournisseur:
Bioss
Description:
This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15551R)
Fournisseur:
Bioss
Description:
Anti-IFI44L Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1555R)
Fournisseur:
Bioss
Description:
This antibody eacts with Escherichia coli O139 (E.coli O139), Escherichia coli is a gram negative bacillus that belongs to a larger group of Enterobacteriae - bacteria that inhabit the gastrointestinal tract. Although usually a harmless resident of the gut, some strains have the potential to cause serious problems, especially where there is an immature immune system or immunosuppression, or where the subtype of organism has acquired the ability to produce pathogenic toxins.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12133R)
Fournisseur:
Bioss
Description:
Anti-SCN3A Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12114R)
Fournisseur:
Bioss
Description:
Anti-CHRND Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11439R)
Fournisseur:
Bioss
Description:
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11445R)
Fournisseur:
Bioss
Description:
Anti-NCF1 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12098R)
Fournisseur:
Bioss
Description:
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. As one of the four major proteins of the NMDA receptor ion channel, GRINA (Glutamate [NMDA] receptor-associated protein 1), also designated NMDA receptor glutamate-binding subunit or putative MAPK-activating protein PM02, is a 371 amino acid multi-pass transmembrane protein. Due to the chromosomal location of the gene encoding GRINA, studies have linked possible GRINA involvement with a form of idiopathic generalized epilepsy.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6790R)
Fournisseur:
Bioss
Description:
Anti-YWHAZ Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10185R)
Fournisseur:
Bioss
Description:
Anti-CMKLR1 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6981R)
Fournisseur:
Bioss
Description:
Anti-CLCN3 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7026R)
Fournisseur:
Bioss
Description:
Anti-HSPE1 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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