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ENZO LIFE SCIENCES
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ENZO LIFE SCIENCES
Description:
Host: Rat, Isotype: IgG2a
Numéro de catalogue:
(ENZOENZ40849)
Fournisseur:
ENZO LIFE SCIENCES
Description:
The Blur 8 BioProbe® labeled probe is prepared by nick translation of a clone of the human alu repeat sequence. Fragment size range: 100-1000 base pairs (as estimated by agarose gel electrophoresis).
UOM:
1 * 2 µG
New Product
Numéro de catalogue:
(ENZOENZ33802)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Wash Buffer Salts can be used in tissue preparations, immunohistochemical staining procedures and in assays that require HRP-linked detection reagents.
UOM:
1 * 3 L
New Product
Numéro de catalogue:
(ENZOENZ40848)
Fournisseur:
ENZO LIFE SCIENCES
Description:
The BK Virus BioProbe® labeled probe is prepared by nick translation of a clone of the entire BK virus genome. BK virus, a simian polyoma virus, is related to SV40 and also bears some similarity to the human virus JC virus. BK virus is highly tumorigenic in hamsters. Fragment size range: 100-1000 base pairs (as estimated by agarose gel electrophoresis).
UOM:
1 * 2 µG
New Product
Numéro de catalogue:
(ENZOENZ42662150)
Fournisseur:
ENZO LIFE SCIENCES
Description:
BIOARRAY™ Deoxyoligo B2 is a synthetic biotin-labelled sequence that can be used in eukaryotic expression assays and in aiding software programs by aligning the grid with the array image.
UOM:
1 * 1 VIA
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
Antifade mounting medium (hardset) is an antifade reagent that causes little or no quenching. Use of the mounting medium significantly extends the photobleaching half-life of the fluorescent stain.
Fournisseur:
ENZO LIFE SCIENCES
Description:
A selective positive allosteric modulator selective for α7 nicotinic acetylcholine receptors (α7 nAChR).
Numéro de catalogue:
(ENZOALX480072M001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Inhibitor of cGMP-dependent protein kinase (PKG) 1α (cGMP antagonist). Resistant against mammalian cyclic nucleotid-dependent phosphodiesterases. No metabolic side effects. Low membrane permeability.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(ENZOALX521006C010)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Isolated from mouse submaxillary glands by a modification of the procedure described by T. Darling, et al.; Cell Culture Meth. Mol. Cell Biol. 4, 79 (1984).
UOM:
1 * 1 EA
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
Anti-HSP90B Rabbit Polyclonal Antibody
Fournisseur:
ENZO LIFE SCIENCES
Description:
Calnexin (CNX), an unglycosylated resident ER transmembrane protein, together with Calreticulin (CRT), plays a key role in glycoprotein folding and its control within the ER, by interacting with folding intermediates via their monoglucosylated glycans. Calnexin associates with newly synthesized monomeric glycoproteins and only recognizes glycoproteins when they are incompletely folded. Furthermore, Calnexin has been demonstrated to function as a molecular chaperone capable of interacting with polypeptide segments of folding glycoproteins.
Fournisseur:
ENZO LIFE SCIENCES
Description:
The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.
Numéro de catalogue:
(ENZOADISPA850F)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Grp94 (Glucose-regulated protein 94) is an abundant resident endoplasmic reticulum (ER) lumenal stress protein, which together with cytosolic Hsp90 belongs to the Hsp90 family of molecular chaperones. Grp94 expression is upregulated by stress conditions such as glucose starvation and heat shock, which promote protein misfolding or unfolding. In addition to a homeostatic role in protein folding and assembly, Grp94 can function in the intracellular trafficking of peptides from the extracellular space to the MHC class I antigen processing pathway of antigen presentation cells.
UOM:
1 * 200 µG
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.
Fournisseur:
ENZO LIFE SCIENCES
Description:
Nonhydrolysable GTP analog.
Fournisseur:
ENZO LIFE SCIENCES
Description:
AACOCF3 is a trifluoromethylketone derivative of arachidonic acid. It is a selective inhibitor of human cytosolic PLA2 and Ca2+-independent PLA2 (iPLA2, IC50=15 µM). It is active in intact platelets and U937 cells (IC50=8 µM). It also inhibits fatty acid amide hydrolase (100% at 7.5 µM).
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