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ENZO LIFE SCIENCES


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Fournisseur:  ENZO LIFE SCIENCES
Description:   Isolated from mouse submaxillary glands by a modification of the procedure described by T. Darling, et al.; Cell Culture Meth. Mol. Cell Biol. 4, 79 (1984).
New Product
Numéro de catalogue: (ENZOADISPA882E)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Hsp65 is a member of the Hsp60 family of heat shock proteins isolated from Mycobacterium bovis BCG. Hsp65 from M. bovis is identical to that of M. tuberculosis, and similar to that of M. leprae, two highly pathogenic strains of mycobacterium. Hsp65 is the immunodominant antigen during mycobacterial infection and vaccination, and has been linked to the development of autoimmune adjuvant arthritis in rats.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (ENZOADISPA850D)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Grp94 (Glucose-regulated protein 94) is an abundant resident endoplasmic reticulum (ER) lumenal stress protein, which together with cytosolic Hsp90 belongs to the Hsp90 family of molecular chaperones. Grp94 expression is upregulated by stress conditions such as glucose starvation and heat shock, which promote protein misfolding or unfolding.
UOM:  1 * 50 µG
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Numéro de catalogue: (ENZOALX804499C100)

Fournisseur:  ENZO LIFE SCIENCES
Description:   The CD14 glycoprotein, gp 55, is present on most monocytic and macrophage like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in mouse serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for endotoxin.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (ENZOALX804743C050)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Host: Rat, Isotype: IgG2a
UOM:  1 * 50 µG
New Product
Numéro de catalogue: (ENZOALX804801BC100)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Host: Mouse, Isotype: IgG1
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (ENZOALX804656R100)

Fournisseur:  ENZO LIFE SCIENCES
Description:   α-synuclein, an acidic neuronal protein of 140 aa, has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and to be an important regulatory component of vesicular transport in neuronal cells. The NAC (non-Aβ component of amyloid plaques) domain (aa 61-95) of α-synuclein is an highly amyloidogenic peptide which was first identified associated with senile plaques in the Alzheimer's disease brain.
UOM:  1 * 100 µl
New Product
Numéro de catalogue: (ENZOALX804530C100)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Capases are a highly conserved family of cysteine proteases and are synthesized as inactive zymogens, which are cleaved at Asp-x sites during apoptosis, generating large and small subunits that heterodimerize to form the active enzyme. Caspase-1 is a member of the ICE/CED-3 family of caspases and is detected in the pro-form as a protein of 45 kDa.
Caspase-1 generates the bioactive form of the pro-inflammatory cytokine IL-1β from its biologically inactive precursor. Overexpression of caspase-1 in cells induces apoptosis, which can be inhibited by cytokine response modifier A (CrmA). Caspase-1 mRNA is predominantly expressed in the spleen and lung and to a lesser extent in skeletal muscle, kidney, testis and heart and within these tissues macrophages preferentially express caspase-1. Caspase-1 deficient mice have no gross abnormalities, however, macrophages from caspase-1-deficient mice are defective in IL-β processing and release.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (ENZOALX804593C100)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Host: Mouse, Isotype: IgG1
UOM:  1 * 1 EA
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Fournisseur:  ENZO LIFE SCIENCES
Description:   Anti-TLR10 Mouse Monoclonal Antibody (RPE (R-Phycoerythrin)) [clone: 3C10C5]
UOM:  1 * 1 EA
New Product

Fournisseur:  ENZO LIFE SCIENCES
Description:   The lymphocyte activation gene-3 (LAG-3, CD223), a member of the immunoglobulin superfamily (IgSF) related to CD4, binds to the major histocompatibility complex (MHC) class II molecules but with higher affinity than CD4. Several alternative mRNA splice-variants of human LAG-3 have been described, two of them encoding potential secreted forms: LAG-3V1 (i.e. the D1-D2 domains of the protein, 36 kDa) and LAG-3V3 (D1-D3, 52 kDa). The longer form was detected by ELISA in the serum of healthy individuals as well as of tuberculosis patients with a favorable outcome. LAG-3 expression by T cell clones correlated with IFN-γ production, and hence soluble LAG-3 has been suggested as a serological marker of Th1 responses.
UOM:  1 * 1 EA
New Product
Fournisseur:  ENZO LIFE SCIENCES
Description:   Inhibitor of both mTORC1 and mTORC2. Induces cell death in human and murine leukemia cells.
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Fournisseur:  ENZO LIFE SCIENCES
Description:   Cell permeable, selective inhibitor of PI 3-Kδ.
New Product
Numéro de catalogue: (ENZOENZCHM1340005)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Cell-permeable, potent and selective GSK-3β inhibitor.
UOM:  1 * 5 mg
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Fournisseur:  ENZO LIFE SCIENCES
Description:   Cell-permeable, potent, selective, and reversible MMP-9 inhibitor.
New Product
Numéro de catalogue: (ENZOENZCHM1820010)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Potent inhibitor of VEGFR-2, MET, Kit and FLT3-ITD
UOM:  1 * 10 mg
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