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ENZO LIFE SCIENCES
Numéro de catalogue:
(ENZOADIVAPSV003E)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Cysteine string protein (CSP) is a 34 kDa rat brain protein localized to the cytoplasmic surface of the synaptic vesicle. CSP is believed to perform similar functions in the assembly of synaptic vesicle proteins which are essential to membrane trafficking.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOALX106008M025)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Does not inhibit nitric oxide synthesis, both <i>in vitro</i> and <i>in vivo</i>.
UOM:
1 * 25 mg
New Product
Numéro de catalogue:
(ENZOALX106006M025)
Fournisseur:
ENZO LIFE SCIENCES
Description:
NOS inhibitor.
UOM:
1 * 25 mg
New Product
Numéro de catalogue:
(ENZOADIKAPGP125E)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Rap1, which is a member of the Ras family of GTP-binding proteins, cycles between an active GTP-bound and an unactive GDP-bound form that is mediated by GTPase activating protein (GAP). Rap1 is proposed to regulate Ras-mediated signaling and may also be involved in the regulation of Integrin-mediated cell adhesion although the mechanism of regulation is not known.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOADIKAPTK140E)
Fournisseur:
ENZO LIFE SCIENCES
Description:
SHPS-1 is a member of the gene family called the signal regulatory proteins of which there are at least fifteen members. SHPS-1 is a substrate of many activated tyrosine kinases such as Insulin receptor and EGFR, amongst others. SHPS-1 has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes.
UOM:
1 * 1 EA
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
Cyclic GMP-dependent protein kinases (PKGs or cGKs) are classified into two types, PKGI and PKGII. Studies have shown that PKGs are highly homologous to PKAs; phosphorylation of cellular proteins by both families of kinases leads to alterations in calcium mobilization, protein phosphatase activity, ion channel function, gene transcription, smooth muscle contractility, and platelet aggregation.
Fournisseur:
ENZO LIFE SCIENCES
Description:
The Akt (PKB) family of protein kinases are serine/threonine kinases, with three mammalian family members identified (Akt1, Akt2, Akt3). Akt is a well-characterized member of PI3 kinase-mediated signaling pathways, regulating cell growth, apoptosis, glycogen synthesis, and other cellular responses through its phosphorylation of downstream substrates. Akt activation is triggered by binding of phospholipid and phosphorylation at two key residues: Thr308 by PDK1, and Ser473 by PDK2, now identified as mTOR. Deregulation of Akt signaling has been associated with cancer, diabetes, and schizophrenia. Akt1 is the cellular homologue of the murine thymoma retroviral oncogene v-akt, and its role in anti-apoptotic and pro-mitotic pathways have made Akt a molecular target for anti-cancer therapeutic intervention. Akt activation inhibits apoptosis by phosphorylating the Bcl-2 related protein Bad, and increases p53 degradation by phosphorylating mdm2. Mitotic substrates of Akt include GSK-3β, p21CIP1, and p27KIP1, cell cycle inhibitors negatively regulated by Akt phosphorylation. Akt has been shown to mediate angiogenesis through regulation of thrombospondins, which may cooperate with pro-mitotic and anti-apoptotic functions of Akt to promote tumorigenesis.
Numéro de catalogue:
(ENZOADIKAPMA003E)
Fournisseur:
ENZO LIFE SCIENCES
Description:
MEK is a dual specificity kinase capable of phosphorylating both tyrosine and threonine residues. The MEK family, which is also known as MAP kinase kinase, phosphorylates MAP kinases on the conserved T-X-Y motif; phosphorylation of MAPK by MEK results in an increase in MAPK activity. MEK is involved in a diverse array of cellular processes such as stress-activated response, apoptosis, cytokine-induced cell proliferation, and DNA recombination during meiosis.
UOM:
1 * 1 EA
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
Anti-USP19 Rabbit Polyclonal Antibody
Numéro de catalogue:
(ENZOENZ40840)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Negative control probe for <i>in situ</i> hybridization.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOADIEKS350)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Rapid DNA damage ELISA kit for cancer, apoptosis and oxidative stress.
UOM:
1 * 1 KIT
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
Irreversible inhibitor of cathepsin L.
Numéro de catalogue:
(ENZOENZABS3000100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Recommended Applications: Flow Cytometry, IF, IHC, WB
Species reactivity: Human, Rat, Monkey, Dog
UOM:
1 * 100 µl
New Product
Numéro de catalogue:
(ENZOENZABS3020001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Digoxigenin (DIG) is a steroid found exclusively in the flowers and leaves of the plants Digitalis purpurea and Digitalis lanata. DIG is the steroid component of digoxin, a cardiac glycoside, and can be conjugated onto a variety of biomolecules (proteins, nucleic acids) to be detected in further assays (e.g. ELISA). These antibodies can be labeled with dyes, enzymes or fluorescence, directly or secondarily, for visualization and detection.
DIG has an advantage over biotin due to the fact that biotin is an endogenous molecule of living cells and plays a key role in many reactions, which can sometimes lead to false positive results. Because the blossoms and leaves of Digitalis plants are the only natural sources of digoxigenin, binding of the anti-digoxigenin antibody in other biological material is not a consideration.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(ENZOENZABS2750100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Recommended Applications: ELISA, WB
Species reactivity: Human
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOENZABS2990100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Recommended Applications: ELISA, IF, IHC (PS), WB
Species reactivity: Human, Mouse
UOM:
1 * 1 EA
New Product
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