ProSci Inc.
Numéro de catalogue:
(PRSI50-250)
Fournisseur:
ProSci Inc.
Description:
Alpha-internexin is a Class IV intermediate filament originally discovered as it co-purifies with other neurofilament subunits. Alpha-internexin is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, having similar protein sequence motifs and a similar intron organization. It is expressed only in neurons and in large amounts early in neuronal development, but is down-regulated in many neurons as development proceeds. Many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M and NF-H. In some mature neurons alpha-internexin is the only neurofilament subunit expressed. Antibodies to alpha-internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. In addition, recent studies show a marked up-regulation of alpha-internexin during neuronal regeneration. The use of antibodies to this protein in the study of brain tumors has not been examined to date, but is likely to be of interest. Recently Cairns et al. used this antibody to show that alpha-internexin is an abundant component of the inclusions of neurofilament inclusion body disease (NFID), a serious human neurodegenerative disorder. The antibody was also used to confirm the presence of circulating auto-antibodies to alpha-internexin in the sera of some patients with endocrine autoimmunity, as well as in some normal individuals.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI46-680)
Fournisseur:
ProSci Inc.
Description:
Anti-KCNJ11 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI46-697)
Fournisseur:
ProSci Inc.
Description:
Anti-APOBEC3A Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI46-687)
Fournisseur:
ProSci Inc.
Description:
Anti-MARK2 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI48-240)
Fournisseur:
ProSci Inc.
Description:
GPR37L1 is an Orphan-A GPCR with an unknown ligand.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI50-143)
Fournisseur:
ProSci Inc.
Description:
Anti-SYNJ1 Mouse Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI50-135)
Fournisseur:
ProSci Inc.
Description:
Anti-OLIG2 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI50-147)
Fournisseur:
ProSci Inc.
Description:
Anti-NR2C2 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI50-149)
Fournisseur:
ProSci Inc.
Description:
Anti-Calb2 Sheep Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI50-172)
Fournisseur:
ProSci Inc.
Description:
Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005; Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors, TRalpha1, TRalpha2, TRbeta1 and TRbeta2. TRalpha1, TRbeta1 and TRbeta2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005).
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI46-773)
Fournisseur:
ProSci Inc.
Description:
Anti-FTL Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI46-769)
Fournisseur:
ProSci Inc.
Description:
Anti-ALOX15 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI46-754)
Fournisseur:
ProSci Inc.
Description:
Anti-PRDX1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI50-215)
Fournisseur:
ProSci Inc.
Description:
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia (Minelli et al., 1995). GAT-1 is thought to play a key role in epileptogenesis (Zhao et al. 2003).
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI71-132)
Fournisseur:
ProSci Inc.
Description:
Anti-SLC12A2 Rabbit Polyclonal Antibody
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI49-328)
Fournisseur:
ProSci Inc.
Description:
Anti-TNFRSF11A Rabbit Polyclonal Antibody
UOM:
1 * 50 µG
Appel de prix
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
![]()
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
![]()
Ces articles ne peuvent être ajoutés au Panier. Veuillez contacter votre service client ou envoyer un e-mail à vwr.be@vwr.com
Une documentation supplémentaire peut être nécessaire pour l'achat de cet article. Un représentant de VWR vous contactera si nécessaire.
Ce produit a été bloqué par votre organisation. Contacter votre service d'achat pour plus d'informations.
Le produit original n'est plus disponible. Le remplacement représenté est disponible
Les produits marqués de ce symbole ne seront bientôt plus disponibles - vente jusqu'à épuisement de stock. Des alternatives peuvent être disponibles en recherchant le code article VWR indiqué ci-dessus. Si vous avez besoin d'une assistance supplémentaire, veuillez contacter notre Service Clientèle au 016 385 011.
|
|||||||||