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ProSci Inc.
Numéro de catalogue:
(PRSI32-179)
Fournisseur:
ProSci Inc.
Description:
Interleukine 6 (IL-6) is a cytokine produced primarily by stimulated monocytes, fibroblasts and epithelial cells. It has a wide variety of biological functions through activating a cellsurface signaling assembly composed of IL6, IL6RA, and the shared signaling receptor gp130. The cytokine plays an essential role in the final differentiation of b-cells into Igsecreting cells, and induces myeloma, plasmacytoma growth, nerve cells differentiations. In addition, IL-6 is an important regulator of acute phase reaction.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXW-7915)
Fournisseur:
ProSci Inc.
Description:
Anti-ZNF256 Chicken Polyclonal Antibody
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI80-026)
Fournisseur:
ProSci Inc.
Description:
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-999)
Fournisseur:
ProSci Inc.
Description:
Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI80-003)
Fournisseur:
ProSci Inc.
Description:
Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI80-002)
Fournisseur:
ProSci Inc.
Description:
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Plays a key role to control cell proliferation in response to cell contact.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI80-034)
Fournisseur:
ProSci Inc.
Description:
Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI36-306)
Fournisseur:
ProSci Inc.
Description:
GPX1 is an antioxidant enzyme that is down-regulated in cancer cells. Protects the hemoglobin in erythrocytes from oxidative breakdown. Its main role is the prevention of cancer initiation by ROS-mediated DNA damage.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI71-296)
Fournisseur:
ProSci Inc.
Description:
Anti-YES1 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
Numéro de catalogue:
(PRSI70-776)
Fournisseur:
ProSci Inc.
Description:
Anti-DYSF Rabbit Polyclonal Antibody
UOM:
1 * 250 µl
Numéro de catalogue:
(PRSI70-742)
Fournisseur:
ProSci Inc.
Description:
Anti-TNFRSF1B Rabbit Polyclonal Antibody
UOM:
1 * 250 µl
Numéro de catalogue:
(PRSI71-363)
Fournisseur:
ProSci Inc.
Description:
Anti-DNAJ Rabbit Polyclonal Antibody
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI31-171)
Fournisseur:
ProSci Inc.
Description:
CREB5 belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. This protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI31-165)
Fournisseur:
ProSci Inc.
Description:
PGR is a member of the steroid receptor superfamily. The protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI31-186)
Fournisseur:
ProSci Inc.
Description:
ETV6 (ETS-related protein Tel1, ETS translocation variant 6 , Tel) is an ETS family transcription factor. This protein contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI42-435)
Fournisseur:
ProSci Inc.
Description:
Anti-ASNSD1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
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