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ProSci Inc.
Numéro de catalogue:
(PRSI45-870)
Fournisseur:
ProSci Inc.
Description:
Anti-MC2R Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5419)
Fournisseur:
ProSci Inc.
Description:
TMEM16A Antibody: Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCC's include the transmembrane proteins TMEM16A and TMEM16B. TMEM16A is expressed in epithelial cells of the kidney and lung, pancreas, and sensory neurons and its mRNA is seen in foregut, airway epithelia, and tracheal smooth muscle; mice lacking TMEM16A fail to survive past ten days and show aerophagia and little weight gain. TMEM16A is also overexpressed or amplified in multiple cancers associated with poor survival such as oral cancers and gastrointestinal stromal tumors, suggesting the development of CaCC modulators may be a viable therapeutic strategy.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5401)
Fournisseur:
ProSci Inc.
Description:
SKA1 Antibody: Upon entry into mitosis, the cell's microtubule (MT) network forms the mitotic spindle, allowing the segregation of paired chromosomes. Proteinaceous structures on centromeric chromatin termed kinetochores (KT) are essential for the proper attachment of the chromosomes to the spindle MTs. A recently discovered spindle and kinetochore complex, comprised of proteins SKA1, SKA2, and SKA3, has been found to be required for stable KT-MT interactions and timely anaphase onset. Depletion of either SKA1 or SKA2 by siRNA results in the loss of both proteins from the KT, but does not impact overall KT structure. Cells depleted of the SKA complex undergo a prolonged checkpoint-dependent delay in a metaphase-like state, indicating the importance of the SKA complex in the maintenance of the metaphase plate and spindle checkpoint silencing.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5397)
Fournisseur:
ProSci Inc.
Description:
Prosapip2 Antibody: Prosapip2 (TBKBP1) is essential for signal transduction during viral infection thus plays a major role in the TNF/NF-kappa B pathway. It is an adaptor protein that constitutively binds TBK1 (TANK-binding kinase) and IKBKE and may play a role in antiviral innate immunity. Prosapip2 is a 615 amino acid adaptor protein belonging to the fibrillar collagen family, consisting of trimers of identical alpha 1 chains which are linked to each other by interchain disulfide bonds. It has a ubiquitous expression with highest levels in ovary, followed by the neuronal system. Prosapip2 binds to TBK1 and helps in the activation of IRF3 which controls the expression of antiviral genes during infection. Recent studies show that Prosapip2 is an interaction partner of ProSAP2/Shank3 and actin, suggesting a role as a linker molecule between postsynaptic density and the cytoskeleton.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5413)
Fournisseur:
ProSci Inc.
Description:
RUSC2 Antibody: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5717P)
Fournisseur:
ProSci Inc.
Description:
APC1 peptide is used for blocking the activity of APC1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5697P)
Fournisseur:
ProSci Inc.
Description:
FAM82A1 peptide is used for blocking the activity of FAM82A1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-697)
Fournisseur:
ProSci Inc.
Description:
The exact function of LOC642623 remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI42-628)
Fournisseur:
ProSci Inc.
Description:
Anti-LY6E Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-115)
Fournisseur:
ProSci Inc.
Description:
Anti-PNKP Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-115)
Fournisseur:
ProSci Inc.
Description:
Human Esterase D is a serine hydrolase that is involved in the detoxification of formaldehyde. Esterase D plays a part in a variety of substrates, including O-acetylated sialic acids, which may involves in the recycling of sialic acids. Esterase D can be used as a genetic marker for retinoblastoma and Wilson’s disease.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-128)
Fournisseur:
ProSci Inc.
Description:
Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family. HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is subsequently converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HO-1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. HO-1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy metals, bromobenzene, endotoxin, oxidizing agents and UVA. HO-1 is involved in the regulation of cardiovascular function and response to a variety of stressors. Defects in HO-1 are the cause of Heme Oxygenase 1 deficiency, resulting in marked erythrocyte fragmentation and intravascular hemolysis, coagulation abnormalities, endothelial damage, and iron deposition in renal and hepatic tissues.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-127)
Fournisseur:
ProSci Inc.
Description:
Glutamate Oxaloacetate Transaminase 1 (GOT1) is a cytoplasmic protein. GOT1 belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. GOT1 is a pyridoxal phosphate-dependent enzyme that exists in cytoplasmic and mitochondrial forms. GOT1 plays a key role in amino acid metabolism and the urea and tricarboxylic acid cycles. GOT1 involves in L-methionine salvage from methylthioadenosine, aspartate catabolic process, cellular response to insulin stimulus, polyamine metabolic process, and glucocorticoid stimulus.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-507)
Fournisseur:
ProSci Inc.
Description:
ERCC8 is a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI35-460)
Fournisseur:
ProSci Inc.
Description:
Anti-E. coli Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate))
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI35-462)
Fournisseur:
ProSci Inc.
Description:
Anti-Influenza Mouse Monoclonal Antibody
UOM:
1 * 1 EA
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