ProSci Inc.
Numéro de catalogue:
(PRSI28-383)
Fournisseur:
ProSci Inc.
Description:
TRIP4 is a transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. TRIP4 plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. TRIP4 acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. It plays a role in androgen receptor transactivation and in testicular function
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI36-094)
Fournisseur:
ProSci Inc.
Description:
CTRP6 mediates the phosphorylation of AMPK and acetyl-CoA carboxylase (ACC) in skeletal muscle cells, subsequently mediating glycogen accumulation and fatty acid oxidation. It induces the expression of the potent anti-inflammatory cytokine IL-10 in macrophages. CTRP6 may be a potential serum marker for hepatocellular carcinoma, contributing to tumor angiogenesis by activating the Akt pathway. CTRP6 was also shown to be associated with obesity, type 1 diabetes mellitus (T1D), vitiligo (depigmentation of the skin) and ASFV (African Swine Fever Virus). CTRP6 forms homotrimers and higher-order oligomers and it may also form heteromeric complexes with CTRP1. May be involved in kidney inflammation.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI36-080)
Fournisseur:
ProSci Inc.
Description:
Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the ‘calreticulin/calnexin cycle’ that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-389)
Fournisseur:
ProSci Inc.
Description:
ZNF446 is a new candidate transcription factor
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-977)
Fournisseur:
ProSci Inc.
Description:
Phosphatidylinositol Transfer Protein alpha Isoform (PITPNA) is found in the cytoplasm and belongs to the PtdIns transfer protein family. PITPNA is a ubiquitous and highly conserved protein in multicellular eukaryotes that catalyzes the exchange of phospholipids between membranes and participates in cellular phospholipid metabolism, signal transduction and vesicular trafficking in vivo. It is expressed in a wide range of tissues and implicated in phospholipase C signaling and in the production of phosphatidylinositol 3, 4, 5-trisphosphate (PIP3) by phosphoinositide-3-kinase.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-972)
Fournisseur:
ProSci Inc.
Description:
SUMO3 belongs to the SUMO protein family and operates like ubiquitin. Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polyer. Nevertheless unlike ubiquitin that targets proteins for degration, SUMO3 takes part in several cellular processess, such as nuclear transport, transcription regulation, apoptosis and protein stability. SUMO3 participates in amyloid beta generation and has a key role in the oneset or progression of Alzheimer's disease.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI48-132)
Fournisseur:
ProSci Inc.
Description:
ADAMTS1 is a Metallopeptidase M12B type protease.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI48-130)
Fournisseur:
ProSci Inc.
Description:
CCXCR1 is a Chemokine Receptor expressed in lymphotactin-responsive leukocyte cells. The viral macrophage inflammatory protein-II, vMIP-II (but not vMIP-I), has been found to be an antagonist of lymphotactin activity at CCXCR1. The CCXCR1 gene is located near the genes for C-C chemokine receptor 9 and SIV/HIV receptor Bonzo on chromosome 3. CCXCR1 is associated with inflammatory and immunological responses by regulating the trafficking of T and B lymphocytes and neutrophils. The up-regulation of CCXCR1 in peripheral T cells is correlated with the inflammatory process observed in Crohns disease.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI46-603)
Fournisseur:
ProSci Inc.
Description:
Anti-XAB2 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI49-800)
Fournisseur:
ProSci Inc.
Description:
Beta 2-microglobulin is the low molecular weight component of HLA antigens and as such is involved in the presentation of endogenous antigens, activation of T lymphocytes and functional emergence of natural killer cells. It is found in the serum of normal individuals and in the urine in elevated amounts in patients with Wilson disease, cadmium poisoning and other conditions leading renal tubular dysfunction. ESTs have been isolated from libraries generated using virtually every tissue in the body.
UOM:
1 * 50 µl
Numéro de catalogue:
(PRSI49-014)
Fournisseur:
ProSci Inc.
Description:
Anti-F8 Mouse Monoclonal Antibody
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6395P)
Fournisseur:
ProSci Inc.
Description:
AP3B2 peptide is used for blocking the activity of AP3B2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5995)
Fournisseur:
ProSci Inc.
Description:
MOX1 Antibody: MOX1, also known as MEOX1, is a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes that is first expressed during gastrulation in the early mesoderm and later in presomitic mesoderm, early somites, dermomyotome and sclerotome. Both MOX1 and the related protein MOX2 are required for proper gene expression in all somitic compartments. MOX1 is an upstream regulator of the transcription factors Bapx1, Tbx18, and Uncx and is thus part of a regulatory circuit that functions in the maintenance of rostrocaudal sclerotome polarity and axial skeleton formation.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI6397P)
Fournisseur:
ProSci Inc.
Description:
TMEM88 peptide is used for blocking the activity of TMEM88 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2107)
Fournisseur:
ProSci Inc.
Description:
DFF40 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. A mouse DNase that causes DNA fragmentation was identified recently and designated CAD (for caspase activated deoxyribonuclease). The human homologue of mouse CAD was more recently identified by three groups independently and termed CPAN, DFF40, and human CAD, respectively. DFF45/ICAD is the inhibitory protein of DFF40/CAD and forms complex with DFF40/CAD. Upon cleavage of DFF45/ICAD by activated caspase, DFF40/CAD is released and activated and eventually causes the degradation of DNA in the nuclei. Activation of DFF40/CAD, which causes DNA degradation, is the hallmark of apoptotic cell death.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI25-433)
Fournisseur:
ProSci Inc.
Description:
ZNF213 may be involved in transcriptional regulation.C2H2 zinc finger proteins, such as ZNF213, have bipartite structures in which one domain binds DNA or RNA and the other modulates target gene expression.
UOM:
1 * 50 µG
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