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Numéro de catalogue:
(PRSI30-231)
Fournisseur:
ProSci Inc.
Description:
ST3GAL2 is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein is normally found in the Golgi but can be proteolytically processed to a soluble form. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4A.The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4A.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI45-937)
Fournisseur:
ProSci Inc.
Description:
Anti-NCF4 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-942)
Fournisseur:
ProSci Inc.
Description:
Anti-NEIL1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI92-429)
Fournisseur:
ProSci Inc.
Description:
Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-binding sites at the C-terminal region and binds heparin with high affinity. The active CXCL4 protein is a tetramer. Human and mouse CXCL4 share 64% sequence identity. CXCL4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair. CXCL4 functions via a splice variant of the chemokine receptor CXCR3, known as CXCR3B. The major physiologic role of CXCL4 appears to be neutralisation of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. In contrast to other CXC chemokines, CXCL4 lacks chemotactic activity for polymorphonuclear granulocytes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-428)
Fournisseur:
ProSci Inc.
Description:
Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in skeletal muscle, tonsils, lymph node, spleen and appendix. KEL has been shown zinc endopeptidase with endothelin-3-converting enzyme activity. It cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. It links via a single disulfide bond to the XK membrane protein that carries the Kx antigen.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-432)
Fournisseur:
ProSci Inc.
Description:
GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It also able to mediate GDNF signalling through the RET tyrosine kinase receptor. It acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4557)
Fournisseur:
ProSci Inc.
Description:
Ambra1 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. Beclin-1, a principal regulator of autophagosome formation, is in turn regulated by Ambra1. Ambra1 associates with Beclin-1 through a region near its center as determined by yeast two-hybrid assay. Null mutations in this gene in mice resulted in embryonic lethality with severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic death. Furthermore, down-regulation of Ambra1 in cultured cells though RNA interference decreased the level of rapamycin- and nutrient starvation-induced autophagy. Multiple isoforms of Ambra1 are known to exist.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI26-086)
Fournisseur:
ProSci Inc.
Description:
SAMSN1 is a member of a novel protein family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains.SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains (Claudio et al., 2001 [PubMed 11536050]).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-096)
Fournisseur:
ProSci Inc.
Description:
MAP4K1 belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily. MAP4K1 may play a role in the response to environmental stress. It appears to act upstream of the JUN N-terminal pathway. MAP4K1 may play a role in hematopoietic lineage decisions and growth regulation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-087)
Fournisseur:
ProSci Inc.
Description:
The exact function of C21orf56 remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4949P)
Fournisseur:
ProSci Inc.
Description:
TOM70 peptide is used for blocking the activity of TOM70 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4945P)
Fournisseur:
ProSci Inc.
Description:
PIG-Y peptide is used for blocking the activity of PIG-Y antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4941P)
Fournisseur:
ProSci Inc.
Description:
LASS6 peptide is used for blocking the activity of LASS6 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4933P)
Fournisseur:
ProSci Inc.
Description:
JPH4 peptide is used for blocking the activity of JPH4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4931P)
Fournisseur:
ProSci Inc.
Description:
JPH3 peptide is used for blocking the activity of JPH3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4943P)
Fournisseur:
ProSci Inc.
Description:
NIPSNAP2 peptide is used for blocking the activity of NIPSNAP2 antibody.
UOM:
1 * 50 µG
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