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ProSci Inc.
Numéro de catalogue:
(PRSI29-517)
Fournisseur:
ProSci Inc.
Description:
EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-369)
Fournisseur:
ProSci Inc.
Description:
Thymidine kinase 1(TK1) belongs to the thymidine kinase family. It is located in the cytoplasm, and phosphorylated on Ser-13 in mitosis during post-translational modification. Two forms of this protein have been identified in animal cells, one in cytosol TK1 and one in mitochondria TK2. Thymidine kinases have a key function in the synthesis of DNA and thereby in cell division, as they are part of the unique reaction chain to introduce deoxythymidine into the DNA. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle, while it is very low in resting cells. TK1 acts as a homotetramer, and can transform thymidime to thymidine 5'-phosphate with the help of ATP.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI42-053)
Fournisseur:
ProSci Inc.
Description:
Anti-Agxt Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI92-373)
Fournisseur:
ProSci Inc.
Description:
Hyaluronan-binding protein 2（HABP2） is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' , but not the gamma-chain of fibrinogen. As a result of this, it does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator to the active two chain form, activates coagulation factor VII.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-372)
Fournisseur:
ProSci Inc.
Description:
T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which are required for their activation. It is the receptor for CD80 and CD86. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. It involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI42-838)
Fournisseur:
ProSci Inc.
Description:
Anti-MBOAT4 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-836)
Fournisseur:
ProSci Inc.
Description:
Anti-SGCD Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-835)
Fournisseur:
ProSci Inc.
Description:
Anti-SAP30L Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI27-074)
Fournisseur:
ProSci Inc.
Description:
The exact functions of C1orf110 remain unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-064)
Fournisseur:
ProSci Inc.
Description:
The specific function of C14orf80 is not yet known.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-078)
Fournisseur:
ProSci Inc.
Description:
SPDYA regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI35-573)
Fournisseur:
ProSci Inc.
Description:
Anti-Flavivirus Mouse Monoclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI25-819)
Fournisseur:
ProSci Inc.
Description:
RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t (3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t (3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4079)
Fournisseur:
ProSci Inc.
Description:
MAPKAP1 Antibody: MAPKAP1 was initially identified as the human homolog of S. pombe SIN1. Recent evidence has shown that it identical to Mip1, a protein that interacts with MEKK2, a member of the mitogen-activated protein kinase (MAPK) intracellular signaling network. MAPKAP1 is thought to prevent MEKK2 activation and dimerization by forming a complex with the inactive and non-phosphorylated MEKK2, thereby blocking the JNK1/2, ERK1/2, p38 and ERK5 MAPKs. MAPKAP1 has also been shown to play a role in the TOR signaling process, a pathway that is involved in controlling cell growth and proliferation in response to environmental cues such as nutrients, growth factors and hormones. Experiments showed that MAPKAP1 helped to maintain the TOR/rictor assembly but not the TOR/RAPTOR complex, which allowed specific phosphorylation of Akt, a kinase that is believed to couple the growth factor-PI3K signaling pathway to the nutrient-regulated TOR signaling pathway. Multiple alternatively spliced isoforms of MAPKAP1 have been identified.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI30-401)
Fournisseur:
ProSci Inc.
Description:
GMPR2 catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. It plays a role in modulating cellular differentiation.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI30-400)
Fournisseur:
ProSci Inc.
Description:
Pseudouridine is an abundant component of rRNAs and tRNAs and is enzymatically generated by isomerization of uridine by pseudouridine synthase.Pseudouridine is an abundant component of rRNAs and tRNAs and is enzymatically generated by isomerization of uridine by pseudouridine synthase (Zucchini et al., 2003 [PubMed 12736709]).
UOM:
1 * 1 EA
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