ProSci Inc.
Numéro de catalogue:
(PRSI28-626)
Fournisseur:
ProSci Inc.
Description:
MTA2 modulates the enzymatic activity of the histone deacetylase core complex.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5273)
Fournisseur:
ProSci Inc.
Description:
MAK10 Antibody: The MAK10 gene encodes a 733-amino acid protein with several regions of similarity to T cell receptor alpha-subunit V (variable) regions in yeast. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species. It is expressed in a variety of tissues in the developing rat embryo but restricted in expression in the adult, remaining detectable only in tissues undergoing continual cell renewal or in cells responding to pathological injury. The MAK10-NAT complex is an essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development. This complex functionally co-assembles in mammalian cells to regulate cell proliferation and is essential for embryonic development, at least in part through the regulation of target of rapamycin (TOR) signaling events. At least two isoforms of MAK10 are known to exist.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI26-801)
Fournisseur:
ProSci Inc.
Description:
LRRC23 contains 5 LRR (leucine-rich) repeats. The exact function of LRRC23 remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-799)
Fournisseur:
ProSci Inc.
Description:
The exact function of LOC134145 remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5603P)
Fournisseur:
ProSci Inc.
Description:
KLF4 pepide is used for blocking the activity of KLF4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI29-296)
Fournisseur:
ProSci Inc.
Description:
PTBP1 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI45-064)
Fournisseur:
ProSci Inc.
Description:
Anti-GIPC1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-069)
Fournisseur:
ProSci Inc.
Description:
Anti-HCRTR1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-062)
Fournisseur:
ProSci Inc.
Description:
Anti-GATA3 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-604)
Fournisseur:
ProSci Inc.
Description:
Teratocarcinoma-derived growth factor 1(TDGF1) is a Cell membrane protein and contains 1 EGF-like domain. The protein plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. It also may play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-607)
Fournisseur:
ProSci Inc.
Description:
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI29-905)
Fournisseur:
ProSci Inc.
Description:
SLC25A29 belongs to the mitochondrial carrier family and it may has palmitoylcarnitine transporting activity.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-911)
Fournisseur:
ProSci Inc.
Description:
SLC1A4 is a transporter for alanine, serine, cysteine, and threonine. It exhibits sodium dependence.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-223)
Fournisseur:
ProSci Inc.
Description:
beta -2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major histocompatibility complex (MHC) class I molecules, involved in the presentation of peptide antigens to the immune system. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis. B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells. Serum B2M concentration is increased in renal diseases, various malignant diseases and some inflammatory and autoimmune disorders. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. B2M has been shown as a marker for monitoring inflammatory disease activity and it appears likely to have a destructive role in amyloidosis-related arthritis. B2M might be involved in the OA (osteoarthritis) pathogenesis. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation. B2M could be a potential therapeutic target in ovarian cancer.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-630)
Fournisseur:
ProSci Inc.
Description:
Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils), and found in liver, fetal liver, bone marrow, placenta, spleen and in lower levels in skeletal muscle, fetal brain and so on. It is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It also binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-633)
Fournisseur:
ProSci Inc.
Description:
platelet receptor Gi24 is a single-pass type I membrane protein, and located at the cell surface. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation. It is participated in the BMP signaling pathway. It also regulates the CD4-pasitive, alpha-beta T cell proliferation, and T cell cytokine production negatively. However, the protein can regulate stem cell differentiation positively.
UOM:
1 * 50 µG
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