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ProSci Inc.


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Fournisseur:  ProSci Inc.
Description:   Anti-Nucleoprotein Rabbit Recombinant Antibody [clone: 84C4a]
UOM:  1 * 0,1 mg
New Product
Numéro de catalogue: (PRSI10-722)

Fournisseur:  ProSci Inc.
Description:   Anti-FG-3019 Human Recombinant Antibody
UOM:  1 * 0,1 mg
New Product
Numéro de catalogue: (PRSI10-731)

Fournisseur:  ProSci Inc.
Description:   Anti-4D11 Recombinant Antibody
UOM:  1 * 0,1 mg
New Product
Numéro de catalogue: (PRSI10-753)

Fournisseur:  ProSci Inc.
Description:   Anti-MG-A271 Recombinant Antibody
UOM:  1 * 0,1 mg
New Product
Numéro de catalogue: (PRSI10-767)

Fournisseur:  ProSci Inc.
Description:   Anti-h2H12ec Recombinant Antibody
UOM:  1 * 0,1 mg
New Product
Numéro de catalogue: (PRSI10-726)

Fournisseur:  ProSci Inc.
Description:   Anti-hPAM4 Recombinant Antibody
UOM:  1 * 0,1 mg
New Product
Numéro de catalogue: (PRSI10-757)

Fournisseur:  ProSci Inc.
Description:   Anti-REGN-1193 Recombinant Antibody
UOM:  1 * 0,1 mg
New Product
Numéro de catalogue: (PRSI10-783)

Fournisseur:  ProSci Inc.
Description:   Anti-LBR-101 Recombinant Antibody
UOM:  1 * 0,1 mg
New Product

Fournisseur:  ProSci Inc.
Description:   This antibody recognises a protein of 185 kDa, which is identified as HER2/ErbB2. Its epitope is localized in the extracellular domain. HER2 is a member of the EGFR family. This antibody is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. HER2/ErbB2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
UOM:  1 * 1 EA
New Product

Fournisseur:  ProSci Inc.
Description:   This antibody recognises an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of TAG-72 Ab with a GCDFP-15 Ab is valuable in the diagnosis of apocrine carcinoma.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (PRSI33-240)

Fournisseur:  ProSci Inc.
Description:   Cytokeratins, also called keratins or simply CKs, are a family of fibrous structural proteins and a major structural component in the outer layer of human skin, as well as hair and nails.  There are 20 human epithelial keratins which can be divided into two subfamiles: acidic and basic (more recent human genone sequencing has identified an additional 20 members). The formation of cytokeratin intermediate filaments requires the pairing of at least one acidic and one basic subfamily member. Members of the same keratin subfamily share extended sequence homology while members of different subfamilies show only limited sequence homology.<p>This antibody is specific for the 56.5 kDa (CK10), 50 kDa (CK14), 50 kDa (CK15), 48 kDa (CK16), and 40 kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Many studies have shown the usefulness of CKs as markers in cancer research and tumor diagnosis, as epithelial tumors generally maintain the same CK expression patterns as their counterpart normal tissue. Clone AE1 is commonly used with clone AE3 as a pan cytokeratin antibody cocktail (<a href=../pan-cytokeratin-antibody-cocktail-ae1-ae3-v2330>Cat No V2330</a>).
UOM:  1 * 1 EA
New Product

Fournisseur:  ProSci Inc.
Description:   This antibody recognises an unidentified antigen in the cytoplasm of mature granulocytes and can be used as a granulocyte marker in normal tissues or inflammatory processes. The granulocyte marker antibody shows no reactivity with any other cell type in human tissues. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. Clone BM-2 mAb reacts with early precursor and mature forms of human myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas.
UOM:  1 * 1 EA
New Product

Fournisseur:  ProSci Inc.
Description:   It reacts with Bromodeoxyuridine (BrdU) in single stranded DNA (produced by partial denaturation of double stranded DNA), BrdU coupled to a protein carrier, as well as free BrdU. BrdU is a thymidine analog, incorporated into cell nuclei during DNA synthesis prior to mitosis. Antibody to Bromodeoxyuridine is helpful in detecting S-phase cells, providing useful information on the aggressiveness of tumors.
UOM:  1 * 1 EA
New Product

Fournisseur:  ProSci Inc.
Description:   Recognises a glycoprotein of 110 kDa, identified as CD26. It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection.
UOM:  1 * 1 EA
New Product

Fournisseur:  ProSci Inc.
Description:   Recognises a single chain glycoprotein of 70 kDa, identified as CD55 (also known as decay accelerating factor, DAF). This mAb was clustered in Kobe at the Sixth International Workshop on Human Leukocyte Differentiation Antigens as F429D-9 (N-L120). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. Anti-CD55 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).
UOM:  1 * 1 EA
New Product

Fournisseur:  ProSci Inc.
Description:   Recognises a glycoprotein of 110 kDa, identified as CD26 (Workshop VI; Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this mAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.
UOM:  1 * 1 EA
New Product
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