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ProSci Inc.
Numéro de catalogue:
(PRSI79-693)
Fournisseur:
ProSci Inc.
Description:
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-709)
Fournisseur:
ProSci Inc.
Description:
Receptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXV-2049)
Fournisseur:
ProSci Inc.
Description:
Anti-Dengue Virus Mouse Monoclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXW-7122)
Fournisseur:
ProSci Inc.
Description:
Corticotropin releasing hormone precursor. CRH is a 41-amino acid peptide derived from a 191-amino acid preprohormone. CRH is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. It is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta CRH is a marker that determines the length of gestation and the timing of parturition and delivery.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI79-682)
Fournisseur:
ProSci Inc.
Description:
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-679)
Fournisseur:
ProSci Inc.
Description:
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXW-7118)
Fournisseur:
ProSci Inc.
Description:
C-myc, v-myc myelocytomatosis viral oncogene homolog. This protein participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence CAC[GA]TG. Seems to activate the transcription of growth-related genes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSIXW-7698)
Fournisseur:
ProSci Inc.
Description:
FUNCTION: Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein found in plasma. Four possible functions are ferroxidase activity, amine oxidase activity, copper transport and homeostasis, and superoxide dismutase activity.
DISEASE: Ceruloplasmin levels are decreased in Wilson disease, in which copper cannot be incorporated into ceruloplasmin in liver because of defects in the copper-transporting ATPase 2.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSIXW-7704)
Fournisseur:
ProSci Inc.
Description:
VLDL transports hepatic synthesized triglycerides and cholesterol. May counteract inhibitory effect of glucocorticoids on arachidonic acid release and prostaglandin I2 formation in vascular smooth muscle cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSIXW-7735)
Fournisseur:
ProSci Inc.
Description:
FUNCTION: Receptor for the C-X-C chemokine SDF-1. Transduces a signal by increasing the intracellular calcium ions level. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodelling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a primary receptor for some HIV-2 isolates and as a coreceptor with CD4 for HIV-1 X4 viruses (lymphocyte-tropic HIV-1 viruses, also called syncytium-inducing (SI) strains). Promotes Env-mediated fusion of the virus.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI79-840)
Fournisseur:
ProSci Inc.
Description:
The 2;5 chromosomal translocation is frequently associated with anaplastic large cell lymphomas (ALCLs). The translocation creates a fusion gene consisting of the ALK (anaplastic lymphoma kinase) gene and the nucleophosmin (NPM) gene: the 3' half of ALK, derived from chromosome 2, is fused to the 5' portion of NPM from chromosome 5. A recent study shows that the product of the NPM-ALK fusion gene is oncogenic. The deduced amino acid sequences reveal that ALK is a novel receptor protein-tyrosine kinase having a putative transmembrane domain and an extracellular domain.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-841)
Fournisseur:
ProSci Inc.
Description:
Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-150)
Fournisseur:
ProSci Inc.
Description:
Nkx6.3 is a new member of the Nkx6 subfamily of homeodomain proteins. Members of the Nkx family of homeodomain proteins are involved in a variety of developmental processes such as cell fate determination in the CNS and in the pancreas. Nkx6.3 is expressed in the developing CNS and gastro-intestinal tract. Nkx6.3 shows a remarkably selective expression in a subpopulation of differentiating V2 neurons at caudal hindbrain levels. In the gut, Nkx6.3 is expressed in duodenal and glandular stomach endoderm and at the end of gestation Nkx6.3 became restricted to the base of the gastric units in the glandular stomach.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI3475)
Fournisseur:
ProSci Inc.
Description:
Caspase-8 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-8 is an initiator caspase that was identified as a member of the Fas/APO-1 death-inducing signaling complex. The adaptor molecule FADD couples procaspase-8 to the Fas receptor death domain; subsequent oligomerization promotes procaspase-8 autoactivation. FLIP, a catalytically inactive caspase-8-like molecule inhibits these interactions and thus can inhibit apoptosis. This antibody will only detect isoform E of caspase-8.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI30-466)
Fournisseur:
ProSci Inc.
Description:
OXCT2 is a testis-specific succinyl-CoA:3-oxoacid CoA transferase (EC 2.8.3.5), which catalyzes the reversible transferof CoA from succinyl-CoA to acetoacetate in the first step of ketone body utilization.OXCT2 is a testis-specific succinyl-CoA:3-oxoacid CoA transferase (EC 2.8.3.5), which catalyzes the reversible transfer of CoA from succinyl-CoA to acetoacetate in the first step of ketone body utilization. See also OXCT1 (MIM 601424).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-115)
Fournisseur:
ProSci Inc.
Description:
Programmed Cell Death Protein 4 (PDCD4) is a member of the PDCD4 family. PDCD4 and EIF4A1 form a heterotrimer. One molecule of PDCD4 binds two molecules of EIF4A1. PDCD4 takes part in apoptosis via inhibiting translation initiation and cap-dependent translation.PDCD4 promotes colonic neoplastic transformation and tumor invasion. PDCD4 is an important target for microrna R-21 in breast cancer cells. Shortage of PDCD4 expression is associated with colorectal cancer. Overexpression of PDCD4 in carcinoid cells results in inhibition of cell proliferation.
UOM:
1 * 50 µG
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