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ProSci Inc.
Numéro de catalogue:
(PRSI3195P)
Fournisseur:
ProSci Inc.
Description:
Caspase-12 peptide is used for blocking the activity of the Caspase-12 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-202)
Fournisseur:
ProSci Inc.
Description:
This protein can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-623)
Fournisseur:
ProSci Inc.
Description:
IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2489)
Fournisseur:
ProSci Inc.
Description:
IL-22 Receptor Antibody: A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified. The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family. IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently. IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-466)
Fournisseur:
ProSci Inc.
Description:
RBM42 belongs to the RRM RBM42 family and it contains 1 RRM (RNA recognition motif) domain. The functions of RBM42 remain unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-762)
Fournisseur:
ProSci Inc.
Description:
The exact functions of DKFZp686E2433 remain unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-129)
Fournisseur:
ProSci Inc.
Description:
FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI27-572)
Fournisseur:
ProSci Inc.
Description:
SIX6 is a member of SIX family. It is the homologue of the chick Six6 (Optx2) gene. SIX6 is closely related to SIX3 and is expressed in the developing and adult human retina.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-574)
Fournisseur:
ProSci Inc.
Description:
SIRT2 is included in class I of the sirtuin family which is characterized by a sirtuin core domain. Human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI27-569)
Fournisseur:
ProSci Inc.
Description:
LHX1 is a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. It may function as a transcriptional regulator and be involved in control of differentiation and development of neural and lymphoid cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-556)
Fournisseur:
ProSci Inc.
Description:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD4 encodes one of the non-ATPase subunits of the 19S regulator lid.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-131)
Fournisseur:
ProSci Inc.
Description:
FGF-23 (Fibroblast growth factor 23) is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralisation. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI54-202)
Fournisseur:
ProSci Inc.
Description:
Anti-PYY Chicken Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI51-435)
Fournisseur:
ProSci Inc.
Description:
Anti-RUNX2 Mouse Monoclonal Antibody
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI54-205)
Fournisseur:
ProSci Inc.
Description:
Anti-GNB3 Chicken Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI54-210)
Fournisseur:
ProSci Inc.
Description:
Anti-RETN Chicken Polyclonal Antibody
UOM:
1 * 100 µl
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