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ProSci Inc.
Numéro de catalogue:
(PRSI4111)
Fournisseur:
ProSci Inc.
Description:
ORAI2 Antibody: Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI3.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI26-433)
Fournisseur:
ProSci Inc.
Description:
A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. BAT5 is thought to be involved in some aspects of immunity.A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. The protein encoded by this gene is thought to be involved in some aspects of immunity.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-443)
Fournisseur:
ProSci Inc.
Description:
DNAJC1 contains 1 J domain and 2 SANT domains. The exact function of DNAJC1 remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-451)
Fournisseur:
ProSci Inc.
Description:
The specific function of MPPE1 is not yet known.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-446)
Fournisseur:
ProSci Inc.
Description:
ARL6IP2 is a multi-pass membrane proteinPotential. It belongs to the GBP family. Atlastin GTPases are required for Golgi apparatus and ER morphogenesis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4545P)
Fournisseur:
ProSci Inc.
Description:
IRGM peptide is used for blocking the activity of IRGM antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4549P)
Fournisseur:
ProSci Inc.
Description:
EVER1 peptide is used for blocking the activity of EVER1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4533P)
Fournisseur:
ProSci Inc.
Description:
LGI2 peptide is used for blocking the activity of LGI2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-884)
Fournisseur:
ProSci Inc.
Description:
ABCC9 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has been associated with this gene thus far. Alternative splicing of this gene results in several products, two of which result from differential usage of two terminal exons and one of which results from exon deletion. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has been associated with this gene thus far. Alternative splicing of this gene results in several products, two of which result from differential usage of two terminal exons and one of which results from exon deletion.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4607P)
Fournisseur:
ProSci Inc.
Description:
Slc35D1 peptide is used for blocking the activity of Slc35D1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI35-675)
Fournisseur:
ProSci Inc.
Description:
Anti-Verotoxins Mouse Monoclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5731)
Fournisseur:
ProSci Inc.
Description:
APC7 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC7 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC7 is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with various transcription coactivators.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5737)
Fournisseur:
ProSci Inc.
Description:
APC11 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC11 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC11, together with APC2 and Ubc4, form the minimal APC ubiquitin ligase module.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5745)
Fournisseur:
ProSci Inc.
Description:
PIAS3 Antibody: The PIAS (protein inhibitor of activated STAT) proteins play a crucial role as transcriptional coregulators in various cellular pathways, including the STAT, p53 and the steroid hormone signaling pathway. The PIAS protein family includes at least five evolutionarily conserved genes, including PIAS3. The major function of the PIAS proteins is the control of gene transcription and can also act as small ubiquitin-like-modifier (SUMO) E3 ligases. PIAS3 binds specifically to STAT3 following the stimulation of STAT3. Increased expression of PIAS3 has been observed in several human cancers, including lung, breast, and brain tumors, but not in anaplastic lymphoma kinase-positive T/null-cell lymphomas, indicating that PIAS3 plays multiple roles in different tissue and cell types.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI6119P)
Fournisseur:
ProSci Inc.
Description:
ZBTB3 peptide is used for blocking the activity of ZBTB3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI1112)
Fournisseur:
ProSci Inc.
Description:
CCR5 Antibody: Human immunodeficiency virus (HIV) and related virus require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. Among them, CCR5 (CC-CKR-5) is a principal coreceptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells. CCR5 is required for the infection by HIV-1, HIV-2, and SIV. The beta-chemokines RANTES, MIP-alpha and MIP-beta are the ligands for CCR5 and prevent infection by M-tropic HIV-1. CXC5 associates with the surface CD4-gp120 of HIV complex and leads to membrane fusion and virus entry of target cells. The amino-terminal domain and the extracellular loops of CCR5 serve as HIV biding sites. CCR5 messenger RNA is expressed in lymphoid organs and monocytes.
UOM:
1 * 1 EA
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