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Numéro de catalogue:
(PRSI29-105)
Fournisseur:
ProSci Inc.
Description:
ZNF394 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 7 C2H2-type zinc fingers, 1 KRAB domain and 1 SCAN box domain. ZNF394 may be involved in transcriptional regulation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3455)
Fournisseur:
ProSci Inc.
Description:
Caspase-5 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1 beta and IL-18. Caspase-5 can interact with caspase-1; both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1 beta. Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-gamma.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI3437)
Fournisseur:
ProSci Inc.
Description:
West Nile Virus Envelope Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway, the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein. The WNV receptor has recently been identified as alpha v beta 3 integrin.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI3445)
Fournisseur:
ProSci Inc.
Description:
Caspase-3 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-3 is synthesized as an inactive proenzyme that undergoes proteolytic cleavage by caspases 8, 9 and 10 to produce 2 subunits, termed p20 and p11. These subunits dimerize to form the active enzyme. Caspase-3 proteolytically cleaves and activates other proteins such as caspases 6, 7 and 9.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-112)
Fournisseur:
ProSci Inc.
Description:
SSBP4 contains 1 LisH domain. The exact function of SSBP4 remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5475P)
Fournisseur:
ProSci Inc.
Description:
SRPX2 peptide is used for blocking the activity of SRPX2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSIXP-5212)
Fournisseur:
ProSci Inc.
Description:
Anti-rpoH Rabbit Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXP-5216BT)
Fournisseur:
ProSci Inc.
Description:
The specific function of this protein remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSIXP-5217BT)
Fournisseur:
ProSci Inc.
Description:
Anti-XCL1 Rabbit Polyclonal Antibody (Biotin)
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI43-070)
Fournisseur:
ProSci Inc.
Description:
Anti-SLC25A38 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5981)
Fournisseur:
ProSci Inc.
Description:
KPNA1 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA1, also known as importin alpha 5, is the alpha subunit of karyopherin, which forms a complex with importin subunit beta-1 and functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. It is ubiquitously expressed and polyubiquitinated in the presence of RAG1. KPNA1 interacts with various virus nucleoproteins, including those of Ebola and influenza.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI25-378)
Fournisseur:
ProSci Inc.
Description:
Vax1 is required for axon guidance and major tract formation in the developing forebrain. Vax1 may contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-383)
Fournisseur:
ProSci Inc.
Description:
ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism. This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6383P)
Fournisseur:
ProSci Inc.
Description:
TEKT5 peptide is used for blocking the activity of TEKT5 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6375P)
Fournisseur:
ProSci Inc.
Description:
TYW2 peptide is used for blocking the activity of TYW2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5955)
Fournisseur:
ProSci Inc.
Description:
NOD6 Antibody: NOD6, also known as NALP9, is a member of the NALP family, a group of proteins that typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD) and are involved in inflammation and innate immune defense. The bovine NOD6, which has 76% homology to its human counterpart, has been suggested to be an oocyte marker gene. In adult tissues, NALP9 mRNA is expressed exclusively in ovary and testis.
UOM:
1 * 1 EA
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