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ProSci Inc.
Numéro de catalogue:
(PRSI79-216)
Fournisseur:
ProSci Inc.
Description:
Involved in stress resistance and actin organization.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-195)
Fournisseur:
ProSci Inc.
Description:
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI2255P)
Fournisseur:
ProSci Inc.
Description:
SnoN peptide is used for blocking activity of SnoN antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2271P)
Fournisseur:
ProSci Inc.
Description:
FLASH peptide is used for blocking the activity of FLASH antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-601)
Fournisseur:
ProSci Inc.
Description:
The function remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-569)
Fournisseur:
ProSci Inc.
Description:
Members of the ARID protein family, including ARID5A, have diverse functions but all appear to play important roles in development, tissue-specific gene expression, and regulation of cell growth.Members of the ARID protein family, including ARID5A, have diverse functions but all appear to play important roles in development, tissue-specific gene expression, and regulation of cell growth (Patsialou et al., 2005 [PubMed 15640446]).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-570)
Fournisseur:
ProSci Inc.
Description:
Members of the ARID protein family, including ARID5A, have diverse functions but all appear to play important roles in development, tissue-specific gene expression, and regulation of cell growth.Members of the ARID protein family, including ARID5A, have diverse functions but all appear to play important roles in development, tissue-specific gene expression, and regulation of cell growth (Patsialou et al., 2005 [PubMed 15640446]).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-589)
Fournisseur:
ProSci Inc.
Description:
PHF13 contains 1 PHD-type zinc finger. The function of the PHF13 protein remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-602)
Fournisseur:
ProSci Inc.
Description:
CDC45L was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7709)
Fournisseur:
ProSci Inc.
Description:
LAMTOR1 is a 161 amino acid membrane protein belonging to the LAMTOR family. It has been identified to interact with and recruit the four Rag GTPases (Rag A-D) to the surface of lysosomes. The mTORC1 kinase complex is a critical component in the regulation of cell growth. As part of the ragulator complex, LAMTOR1 recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids. LAMTOR1 may be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes / lysosomes.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI6391)
Fournisseur:
ProSci Inc.
Description:
AP3S1 Antibody: AP3S1 belongs to the adaptor complexes 3 (AP3) small subunit family which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3 is an heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). AP3S1 Interacts with AGAP1 and may play an important role in carcinoma.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI26-239)
Fournisseur:
ProSci Inc.
Description:
EMX1 belongs to the EMX homeobox family.It is transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. The protein may function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI79-821)
Fournisseur:
ProSci Inc.
Description:
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXW-7698)
Fournisseur:
ProSci Inc.
Description:
FUNCTION: Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein found in plasma. Four possible functions are ferroxidase activity, amine oxidase activity, copper transport and homeostasis, and superoxide dismutase activity.
DISEASE: Ceruloplasmin levels are decreased in Wilson disease, in which copper cannot be incorporated into ceruloplasmin in liver because of defects in the copper-transporting ATPase 2.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSIPM-4527)
Fournisseur:
ProSci Inc.
Description:
PUMA Monoclonal Antibody: Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse. PUMA/bbc3 is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMAα and PUMAβ. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIPM-4845)
Fournisseur:
ProSci Inc.
Description:
MD-2 Monoclonal Antibody: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
UOM:
1 * 1 EA
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