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ProSci Inc.
Numéro de catalogue:
(PRSI33-129)
Fournisseur:
ProSci Inc.
Description:
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including alpha and beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER alpha and beta are differentially activated by various ligands. Ligand interaction triggers a cascade of events, including dissociation from heat shock proteins, recepter dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER alpha and beta may be regulated by distinct mechanisms even though they share many functional characteristics.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-148)
Fournisseur:
ProSci Inc.
Description:
This antibody recognises a protein of 75 kDa, identified as the mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. The antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI62-391)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI62-384)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI62-387)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI57-420)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:2000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50 For FACS starting dilution is: 1:10~50
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI76-835)
Fournisseur:
ProSci Inc.
Description:
The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A. CD161 is expressed on most natural killer cells, subsets of CD4+ and CD8+ T lymphocytes, gamma delta TCR T lymphocytes, a subset of CD3+ thymocytes, and especially on CD45RO+ T lymphocytes. Reports indicate that it may serve as a specific receptor for some natural killer cell targets and a possible stimulatory role.
UOM:
1 * 25 Tests
New Product
Numéro de catalogue:
(PRSI60-075)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI60-070)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI76-817)
Fournisseur:
ProSci Inc.
Description:
The H1.2F3 monoclonal antibody specifically reacts with human CD69, the 27 to 33 kDa type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI60-067)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI60-832)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI60-827)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI55-940)
Fournisseur:
ProSci Inc.
Description:
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI33-313)
Fournisseur:
ProSci Inc.
Description:
This mAb recognises a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This mAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-304)
Fournisseur:
ProSci Inc.
Description:
Recognises a 180-185 kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.
UOM:
1 * 1 EA
New Product
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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