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STEMCELL Technologies
Fournisseur:
STEMCELL Technologies
Description:
Hamster (Armenian) monoclonal IgG2 antibody against mouse T cell receptor gamma/delta, PE-conjugated.
Fournisseur:
STEMCELL Technologies
Description:
Interleukin 6 (IL-6) is a pleiotropic growth factor with the wide range of biological activities in immune regulation, hematopoiesis, and oncogenesis. IL-6 is produced by a variety of cell types including T cells, B cells, monocytes and macrophages, fibroblasts, hepatocytes, vascular endothelial cells, and various tumor cell lines. On its own or in combination with other factors such as IL-2 and interferon-γ, IL-6 stimulates the proliferation of B cells, T cells, and hybridoma cells (Hirano <i>et al.</i>; Mihara <i>et al.</i>; Tanaka et al). In combination with cytokines such as IL-3, GM-CSF and SCF, IL-6 has been shown to promote hematopoietic progenitor cell proliferation and differentiation in vitro. IL-6 signals through a cell surface type I cytokine receptor complex consisting of the ligand-binding IL-6α (CD126) and the signal-transducing gp130 subunits. The binding of IL-6 to its receptor system includes activation of JAK/STAT signaling pathway (Mihara <i>et al.</i>; Peters <i>et al.</i>; Tanaka <i>et al.</i>).
Fournisseur:
STEMCELL Technologies
Description:
Interferon-gamma (IFN-γ), also known as type II interferon, is produced by T and NK cells, and in smaller amounts by dendritic cells and macrophages. IFN-γ is controlled by cytokines such as IL-12 and IL-18 secreted in response to infection (Schroder <i>et al.</i>). IFN-γ binds to a receptor complex and initiates signal transduction via the JAK/STAT pathway; this culminates in the transcription and activation of many genes that control a diverse array of immunological functions (De Weerd and Nguyen; Krause <i>et al.</i>). IFN-γ stimulates the antimicrobial and anti-tumor activity of macrophages, NK cells, and neutrophils (Billiau and Matthys) by promoting the activation of microbial effector functions such as production of reactive oxygen species, NO intermediates, complement, etc. (Schroder <i>et al.</i>). IFN-γ enhances MHC class I and II expression in dendritic cells and mononuclear phagocytes, as well as the production of IL-12 by dendritic cells. In B cells, IFN-γ stimulates survival and growth in both mouse and human cells, and redirects B cells from proliferation towards differentiation. IFN-γ favors the development of Th1 vs Th2 cells and stimulates monocyte differentiation and function (Schroder <i>et al.</i>).
Fournisseur:
STEMCELL Technologies
Description:
Mouse monoclonal IgG1 antibody against human, cynomolgus, cow CD117 (c-Kit), unconjugated.
Fournisseur:
STEMCELL Technologies
Description:
Mouse monoclonal IgG1 antibody against human, rhesus, sooty mangabey CD123 (IL-3Rα), unconjugated.
Fournisseur:
STEMCELL Technologies
Description:
Neurotrophin-3 (NT-3) is a neurotrophic factor and a member of the nerve growth factor (NGF) family of proteins that includes neuron growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-4/5. NT-3 signals a number of trophic effects through its transducing receptor tyrosine kinase TrkC. NT-3 is known to promote survival, development, and differentiation of neurons, and modulates transmitter release at several types of synapses in the peripheral and central nervous systems (Chalazonitis 1996). NT-3 has been shown to have an important role in the overall development of enteric neurons, which are crucial for gut peristalsis (Chalazonitis 2004). Studies in rats have shown the potential of NT-3 in dorsal column axonal regeneration (Bradbury <i>et al.</i>). NT-3 was shown to protect neurons against amyloid-β toxicity (Lesne <i>et al.</i>). NT-3 has applications in neuronal differentiation protocols to generate β-tubulin III+ peripheral neurons from neural crest stem cells (Menendez <i>et al.</i>) and oligodendrocyte precursor cells from human embryonic stem (ES) and induced pluripotent stem (iPS) cells (Douvaras <i>et al.</i>).
Fournisseur:
STEMCELL Technologies
Description:
Rat monoclonal IgG1, kappa isotype control antibody, APC-conjugated.
Fournisseur:
STEMCELL Technologies
Description:
Rat monoclonal IgG1, kappa isotype control antibody, PE-conjugated.
Fournisseur:
STEMCELL Technologies
Description:
Rat monoclonal IgG2a antibody against mouse CD19, PE-conjugated.
Numéro de catalogue:
(STMC05411)
Fournisseur:
STEMCELL Technologies
Description:
Medium for detection of CFU-F and expansion of human mesenchymal stem cells.
UOM:
1 * 1 KIT
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Fournisseur:
STEMCELL Technologies
Description:
Rat monoclonal IgG2a antibody against mouse CD19, APC-conjugated.
Fournisseur:
STEMCELL Technologies
Description:
Mouse monoclonal IgG2a antibody against human, mouse, rat beta-tubulin III, unconjugated.
Fournisseur:
STEMCELL Technologies
Description:
Immunomagnetic positive selection of human CD3+ cells (e.g. T cells).
Fournisseur:
STEMCELL Technologies
Description:
Immunomagnetic isolation of untouched mouse pan-B cells
Fournisseur:
STEMCELL Technologies
Description:
Immunomagnetic positive selection of CD4+ T cells from mouse splenocytes or other tissues.
Fournisseur:
STEMCELL Technologies
Description:
Rat monoclonal IgG2b antibody against mouse CD45, Alexa Fluor® 488-conjugated.
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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