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Tonbo Biosciences
Numéro de catalogue:
(70-8077-M002)
Fournisseur:
Tonbo Biosciences
Description:
Rabbit anti-mouse IgG (H&L) - Affinity Pure, min x w/human serum proteins
UOM:
1 * 2 mg
Numéro de catalogue:
(72-8076-M001)
Fournisseur:
Tonbo Biosciences
Description:
Rabbit anti-Mouse IgG (H&L) - Affinity Pure, HRP Conjugate
UOM:
1 * 1 mg
Numéro de catalogue:
(72-8111-M001)
Fournisseur:
Tonbo Biosciences
Description:
Goat anti-Guinea Pig IgG (H&L) - Affinity Pure, HRP Conjugate
UOM:
1 * 1 mg
Numéro de catalogue:
(30-8026-M001)
Fournisseur:
Tonbo Biosciences
Description:
Goat anti-Human IgE (epsilon chain) - Affinity Pure, Biotin Conjugate
UOM:
1 * 1 mg
Numéro de catalogue:
(30-8027-M001)
Fournisseur:
Tonbo Biosciences
Description:
Goat anti-Human IgE (epsilon chain) - Affinity Pure, Biotin Conjugate, min x w/bovine, mouse or rabbit serum proteins
UOM:
1 * 1 mg
Numéro de catalogue:
(35-8016-M001)
Fournisseur:
Tonbo Biosciences
Description:
Goat anti-Human IgA (alpha chain) - Affinity Pure, FITC Conjugate
UOM:
1 * 1 mg
Numéro de catalogue:
(30-8057-U500)
Fournisseur:
Tonbo Biosciences
Description:
Goat anti-Mouse IgG (H&L) - F(ab')2 fragment, Biotin Conjugate, min x w/bovine, goat, human, rabbit, or rat IgG
UOM:
1 * 0,5 mg
Numéro de catalogue:
(70-8015-M001)
Fournisseur:
Tonbo Biosciences
Description:
Goat anti-Human IgA (alpha chain), F(ab')2 Fragment - Affinity Pure
UOM:
1 * 1 mg
Numéro de catalogue:
(30-8054-U500)
Fournisseur:
Tonbo Biosciences
Description:
Goat anti-mouse IgG (H&L), F(ab')2 fragment - Affinity Pure, Biotin Conjugate
UOM:
1 * 0,5 mg
Numéro de catalogue:
(80-4724-U100)
Fournisseur:
Tonbo Biosciences
Description:
The C1.18.4 immunoglobulin is useful as an isotype-matched control. The C.1.18.4 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2a antibodies.
UOM:
1 * 1 EA
Numéro de catalogue:
(70-4321-U100)
Fournisseur:
Tonbo Biosciences
Description:
Purified Rat IgG2a Isotype Control (2A3)
UOM:
1 * 1 EA
Fournisseur:
Tonbo Biosciences
Description:
The Hit8a antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.
Fournisseur:
Tonbo Biosciences
Description:
The 2H7 antibody reacts with human CD20, expressed by pre-B cells, resting and activated B cells, follicular dendritic cells and a small subset of T cells, but not on plasma cells. CD20 is a 33-37 kDa transmembrane protein which is differentially phosphorylated in resting and active B cells. The CD20 molecule plays a role in regulating B-cell activation.
Fournisseur:
Tonbo Biosciences
Description:
The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1 (Ehlers et al. 2012. Endocrinology. 10: 1247).
Fournisseur:
Tonbo Biosciences
Description:
The BNI3 antibody is specific for human CD152, commonly known as CTLA-4, a 33 to 37 kDa protein expressed as a homodimer on the surface of activated T and B cells, and on thymocytes. CTLA-4 is structurally similar, yet functionally disparate, to the T cell co-stimulatory molecule CD28. Both CTLA-4 and CD28 interact with the co-stimulatory molecules CD80 (B7-1) and CD86 (B7-2) on antigen-presenting cells, with CTLA-4 displaying a higher avidity than CD28. While CD28 typically delivers a potent co-stimulatory signal in support of T cell activation, CTLA-4 appears to act as a negative regulator of T cell activation and may contribute to the suppressor function of Treg cells.
Fournisseur:
Tonbo Biosciences
Description:
The GK1.5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells
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