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Protéines et Peptides
Numéro de catalogue:
(PRSI1148P)
Fournisseur:
ProSci Inc.
Description:
DFF45 peptide is used for blocking the activity of DFF45 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7195P)
Fournisseur:
ProSci Inc.
Description:
15 amino acids near the carboxy terminus of human STAT1.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3559P)
Fournisseur:
ProSci Inc.
Description:
CTRP2 peptide is used for blocking the activity of the CTRP2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-370)
Fournisseur:
ProSci Inc.
Description:
B7-H4 is a B7 family member that negatively regulates T cell immunity by inhibiting of T cell proliferation, cytokine production and cell cycle progression. In vitro, B7-H4 inhibits CD4+ and CD8+ T cell proliferation, cytokine production and generation of alloreactive cytotoxic T cells (CTLs). In vivo, blockade of endogenous B7-H4 by specific monoclonal antibody promotes T cell responses. B7-H4 ia an important negative regulator of innate immunity through growth inhibition of neutrophils. B7-H4 is expressed on some tumour cancer cells. The role of B7-H4 in tumour progression may be to transform precancerous cells and then protect them from immunosurveillance.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI92-007)
Fournisseur:
ProSci Inc.
Description:
Maleylacetoacetate Isomerase (MAAI) belongs to the Glutathione S-Transferase super-family. MAAI encodes multifunctional enzymes in the detoxification of electrophilic molecules by conjugation with glutathione, for example, mutagens, carcinogens and several therapeutic drugs. MAAI is a bifunctional protein with low glutathione peroxidase activity with T-butyl and cumene hydroperoxides. MAAI can catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. But it has minimal glutathione-conjugating activity with 7-chloro-4-nitrobenz-2-oxa-1, ethacrynic acid 3-diazole and maleylacetoacetate isomerase activity.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-418)
Fournisseur:
ProSci Inc.
Description:
Cystatin-SN is a member of family 2 of the Cystatin superfamily and a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid. Together with Cystatins S and SA, it is produced by the salivary gland and secreted largely in the submandibular/sublingual saliva. Cystatin-SN inhibits members of the Papain family including Cathepsins B, C, H and L.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-453)
Fournisseur:
ProSci Inc.
Description:
Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein. SUMF1 is a Ca2+-binging member of the sulfatase-modifying factor family. SUMF1 is a soluble ER lumenal glycoprotein, it converts inactive sulfatases into an active form by transforming a catalytic site cysteine into a formylglycine residue. In the ER, SUMF1 can exist as either a monomer, or a disulfide-linked homodimer or a heterodimer with SUMF2. Three splice isoforms are known.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-537)
Fournisseur:
ProSci Inc.
Description:
Interleukin-20 Receptor Subunit alpha (IL20RA) is a single-pass type I membrane protein that is a member of the type II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29 amino acid signal peptide, a 221 amino acid extracellular domain with two fibronectin type-III domains, a 24 amino acid transmembrane region, and a 279 amino acid intracellular domain. IL20RA is widely expressed with highest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB, and the complex serves as a receptor for IL19, IL20 and IL24. IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-165)
Fournisseur:
ProSci Inc.
Description:
Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2136P)
Fournisseur:
ProSci Inc.
Description:
APP peptide is used for blocking the activity of APP antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5531P)
Fournisseur:
ProSci Inc.
Description:
INCA1 peptide is used for blocking the activity of INCA1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5721P)
Fournisseur:
ProSci Inc.
Description:
APC2 peptide is used for blocking the activity of APC2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5695P)
Fournisseur:
ProSci Inc.
Description:
ENC-2 peptide is used for blocking the activity of ENC-2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5723P)
Fournisseur:
ProSci Inc.
Description:
APC3 peptide is used for blocking the activity of APC3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4799P)
Fournisseur:
ProSci Inc.
Description:
Akirin1 peptide is used for blocking the activity of Akirin1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-513)
Fournisseur:
ProSci Inc.
Description:
Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. Complex formation between IL-21R and the common gamma chain (gammac) is required for signalling. IL-21R is expressed mainly on B cells (highest on mature, activated, follicular and germinal center B cells), NK cells and activated T cells, but is also found on dendritic cells, alternatively activated macrophages, intestinal lamina propria fibroblasts and epithelial cells and keratinocytes. B cell IL-21R engagement induces Blimp1 (which mediates plasma cell differentiation) and is important for memory responses. IL-21R engagement on mouse NK cells enhances their cytotoxic activity and IFN-gamma production. IL-21R engagement on CD8+ T cells aids control of viral infection and tumour growth; IL-21R is also necessary for sufficient numbers of regulatory T cells to combat chronic inflammation. IL-21R expression is often upregulated in allergic skin inflammation, systemic lupus erythematosus and diffuse large B cell lymphoma (DLBCL).
UOM:
1 * 25 µG
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