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Protéines et Peptides
Numéro de catalogue:
(PRSI91-475)
Fournisseur:
ProSci Inc.
Description:
Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-346)
Fournisseur:
ProSci Inc.
Description:
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-355)
Fournisseur:
ProSci Inc.
Description:
Secreted Protein Acidic and Rich in Cysteine (SPARC) is a secreted, evolutionarily conserved collagen-binding glycoprotein and belongs to the SPARC family. SPARC has 286 amino acids and contains an EF-hand in C-termina domain, a follistatin-like domain with Kazal-like sequences. There are two calcium binding sites, one binds 5 - 8 Ca2+ with a low affinity and other on an EF-hand loop that binds a Ca2+ ion with a high affinity. It is highly expressed in tissues undergoing morphogenesis, remodeling and wound repair. SPARC regulate cell growth through interactions with the extracellular matrix (ECM) and cytokines. SPARC bind to numerous proteins of the ECM, affect ECM protein expression, influence cellular adhesion and migration, and modulate growth factor-induced cell proliferation and angiogenesis. SPARC also binds several types of collagen, albumin, thrombospondin, PDGF and cell membranes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6083P)
Fournisseur:
ProSci Inc.
Description:
ZIP2 peptide is used for blocking the activity of ZIP2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6003P)
Fournisseur:
ProSci Inc.
Description:
ZNF346 peptide is used for blocking the activity of ZNF346 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6081P)
Fournisseur:
ProSci Inc.
Description:
ZIP1 peptide is used for blocking the activity of ZIP1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-354)
Fournisseur:
ProSci Inc.
Description:
Nuclear NMNAT isoform. Catalyses the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI4457P)
Fournisseur:
ProSci Inc.
Description:
Slitrk2 peptide is used for blocking the activity of Slitrk2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6777P)
Fournisseur:
ProSci Inc.
Description:
YPEL4 peptide is used for blocking the activity of YPEL4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3415P)
Fournisseur:
ProSci Inc.
Description:
Anthrax peptide is used for blocking the activity of Anthrax lethal factor antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3411P)
Fournisseur:
ProSci Inc.
Description:
Anthrax peptide is used for blocking the activity of Anthrax PA antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3409P)
Fournisseur:
ProSci Inc.
Description:
XAF-1 peptide is used for blocking the activity of XAF-1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-765)
Fournisseur:
ProSci Inc.
Description:
Lymphocyte Antigen 6H (LY6H) is a novel member of the LY6 family of glycosylphosphatidylinositol-anchored cell surface glycoproteins. LY6H contains one UPAR/Ly6 domain. Human LY6H is synthesized as a 140 amino acid precursor that contains a 25 amino acid signal sequence, 20 amino acid propeptide that is removed in the mature form, and a 90 amino acid mature chain. LY6H is highly expressed in the brain (cerebral cortex, amygdala, hippocampus and subthalamic nucleus) and in acute human leukemic cell line MOLT-3. It is also found in lower levels in testis, pancreas, small intestine and colon. It has been shown that LY6H may play a role in both the central nervous system and the immune system.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-767)
Fournisseur:
ProSci Inc.
Description:
Endoplasmic reticulum resident protein 27, also known as ER protein 27, C12orf46 and ERP27, is an endoplasmic reticulum luminal protein which is a member of the protein disulfide isomerase family. ERP27 contains one thioredoxin domain and does not contain a CXXC active site motif. ERP27 is widely expressed in many tissues; it has highest expression in pancreas, with lower levels in spleen, lung, kidney, thymus, and bone marrow. ERP27 interacts with PDIA3 and binds somatostatin-14 via hydrophobic interactions. ERP27 may act as a protease, protein disulfide isomerase, thiol-disulfide oxidase or phospholipase.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-596)
Fournisseur:
ProSci Inc.
Description:
Programmed cell death 1 ligand 1 (PD-L1) is also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1), is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses. B7-H1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. PD-L1 is highly expressed in the heart, skeletal muscle, placenta and lung and weakly expressed in the thymus, spleen, kidney and liver. PD-L1 is expressed on activated T-cells, B-cells, dendritic cells, keratinocytes and monocytes. PD-L1 is up-regulated on T- and B-cells, dendritic cells, keratinocytes and monocytes after LPS and IFNG activation and up-regulated in B-cells activated by surface Ig cross-linking. PD-L1 involve in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-592)
Fournisseur:
ProSci Inc.
Description:
Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.
UOM:
1 * 1 EA
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