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Protéines et Peptides
Numéro de catalogue:
(PRSI90-359)
Fournisseur:
ProSci Inc.
Description:
Tryptophan 2,3-dioxygenase (TDO) is a heme-containing dioxygenase catalyzing the addition of molecular oxygen across the 2,3-double bond of the indole ring of tryptophan to form N-formylkynurenine (NFK). In Anopheles gambiae, TDO is the only enzyme able to catalyze the first and rate-limiting step in L-Trp catabolism through the kynurenine pathway. Tryptophan is an essential amino acid for protein synthesis and also the precursor for production of a number of neurotransmitters, such as serotonin and melatonin; in mosquitoes, the kynurenine pathway is essential for eye pigmentation. Conceivably, the tryptophan-using pathways should be regulated in a coordinated manner in mosquitoes as well as in other species and TDO activation/inactivation processes could play an essential role in these phenomena.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3911P)
Fournisseur:
ProSci Inc.
Description:
Avian influenza hemagglutinin 2 peptide is used for blocking activity of avian influenza hemagglutinin 2 antibody. It usually blocks antibody activity completely in ELISA assays by incubating peptide with equal volume of antibody for 30 min at 37 °C antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3963P)
Fournisseur:
ProSci Inc.
Description:
sRANK-L peptide is used for blocking activity of sRANK-L antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-297)
Fournisseur:
ProSci Inc.
Description:
CD46 is a type I membrane protein containing four Sushi domains. CD46 is expressed by all cells except erythrocytes. CD46 has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46. CD46 acts as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-306)
Fournisseur:
ProSci Inc.
Description:
Cysteine-rich secretory protein 3 (CRISP-3) is a secreted protein,containing 1 SCP domain and 1 ShKT domain.It is belongs to the CRISP family. CRISP-3 is a glycoprotein that belongs to the family of cysteine-rich secretory proteins (CRISPs) which was originally discovered in human neutrophilic granulocytes. CRISP-3 is also widely distibuted in exocrine glands (salivary glands, pancreas and prostate), eosinophilic granulocytes and to a lower level in epididymis, ovary, thymus and colon. The presence of CRISP-3 in neutrophils, eosinophils and in exocrine secretions indicates a role in innate host defense. The antibody has been raised against recombinant C-terminally truncated form of CRISP-3 and recognizes both the N-glycosylated and non-glycosylated form of the mature protein.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-299)
Fournisseur:
ProSci Inc.
Description:
Inter-Cellular Adhesion Molecule 1 (ICAM1) is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells. As an endothelial and leukocyte-associated transmembrane protein, ICAM1 is well known for its importance in stabilizing cell-cell interactions and facilitating leukocyte endothelial transmigration. The presence of heavy glycosylation and other structural characteristics lend ICAM1 binding sites for a number of immune-associated ligands. Notably, ICAM-1 binds to macrophage adhesion ligand-1 (Mac-1; ITGB2 / ITGAM), leukocyte function associated antigen-1 (LFA-1/integrin), and fibrinogen.ICAM-1 expressed by respiratory epithelial cells is also the binding site for rhinovirus, the causative agent of most common colds.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-988)
Fournisseur:
ProSci Inc.
Description:
WW Domain-Binding Protein 2 (WBP2) is a ubiquitous protein that contains one GRAM domain. The WW domain is composed of 38 to 40 semi-conserved AA shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is participated in mediating protein-protein interactions. WBP2 binds to the WW domain of YAP1, WWP1 and WWP2. The WW-binding 1 motif of WBP2 mediates interaction with NEDD4. The function of this protein WBP2 has not been determined. Some researches demonstrate that WBP-2 also interacts with the thyroid-specific transcription factor Pax8.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4337P)
Fournisseur:
ProSci Inc.
Description:
Strep-tag II peptide is used for blocking the activity of strep-tag II antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4321P)
Fournisseur:
ProSci Inc.
Description:
CCDC98 peptide is used for blocking the activity of CCDC98 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-458)
Fournisseur:
ProSci Inc.
Description:
Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene, belongs to the protease inhibitor I35 (TIMP) family. The protein complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6985P)
Fournisseur:
ProSci Inc.
Description:
BCL6 peptide is used for blocking the activity of BCL6 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-689)
Fournisseur:
ProSci Inc.
Description:
Golgi Membrane Protein 1 (GOLM1) belongs to the GOLM1/CASC4 family, GOLM1 is a single-pass type II membrane protein and can be found in many tissues . GOLM1 is overexpressed in prostate cancer and lung adenocarcinoma tissue. GOLM1 can be up-regulated in response to viral infection. GOLM1 is induced by the E1A adenoviral protein. GOLM1 plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI40-123)
Fournisseur:
ProSci Inc.
Description:
GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic β-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2. Recombinant human GLP-1 is a 3.3 kDa consisting of 31 amino acid residues.
UOM:
1 * 200 µG
Numéro de catalogue:
(PRSI5549P)
Fournisseur:
ProSci Inc.
Description:
NAT11 peptide is used for blocking the activity of NAT11 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3495P)
Fournisseur:
ProSci Inc.
Description:
GβL peptide is used for blocking the activity of GβL antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI40-566)
Fournisseur:
ProSci Inc.
Description:
NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues). Manufactured using all non-animal reagents.
UOM:
1 * 1 EA
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