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Protéines et Peptides
Numéro de catalogue:
(PRSI2469P)
Fournisseur:
ProSci Inc.
Description:
IL-21 receptor peptide is used for blocking the activity of IL-21 receptor antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2447P)
Fournisseur:
ProSci Inc.
Description:
MTBP peptide is used for blocking the activity of MTBP antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2479P)
Fournisseur:
ProSci Inc.
Description:
MCG10 peptide is used for blocking the activity of MCG10 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6235P)
Fournisseur:
ProSci Inc.
Description:
ZIMP7 peptide is used for blocking the activity of ZIMP7 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-013)
Fournisseur:
ProSci Inc.
Description:
Bridging Integrator 2 (BIN2) is a cytoplasmic protein. BIN2 contains one BAR domain and Interacts with BIN1. BIN2 is highly expressed in some hematopoietic tissues, including peripheral blood, thymus, colon and placenta. BIN2 is an Arabidopsis GSK3-like kinase that negatively regulates brassinosteroid (BR) signaling. Genetic studies show that BIN2 is inhibited in response to BR perception at the cell surface to relieve its inhibitory effects on downstream targets.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-014)
Fournisseur:
ProSci Inc.
Description:
60S Ribosome Subunit Biogenesis Protein NIP7 Homolog (NIP7) belongs to the NIP7 family. NIP7 contains one PUA domain, it is essential for the process of proper 27S pre-rRNA and 60S ribosome subunit assembly. NIP7 is a monomer form and interacts with NOL8 and SBDS, and may bind to RNA. In addition, NIP7 is one of the many trans-acting factors required for eukaryotic ribosome biogenesis, which interacts with nascent pre-ribosomal particles and dissociates as they complete maturation and are exported to the cytoplasm.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-593)
Fournisseur:
ProSci Inc.
Description:
Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-V. PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. In vitro, treatment of anti-CD3 stimulated T cells with PD-L1-Ig results in reduced T cell proliferation and IFN-γ secretion. Monoclonal antibodies targeting PD-1 that boost the immune system are being developed for the treatment of cancer.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI3657P)
Fournisseur:
ProSci Inc.
Description:
IRE1p peptide is used for blocking the activity of IRE1p antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3661P)
Fournisseur:
ProSci Inc.
Description:
TRAF2 peptide is used for blocking the activity of TRAF2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3669P)
Fournisseur:
ProSci Inc.
Description:
BAP29 peptide is used for blocking the activity of BAP29 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-330)
Fournisseur:
ProSci Inc.
Description:
Meteorin-like (cometin; subfatin) is a potent new neurotrophic factor promoting neurite outgrowth from dorsal root ganglion cells. Meteorin-like is also a novel adipokine expressed by adipose tissue being downregulated upon caloric restriction. Meteorin-like is secreted by muscles during exercise and converts white adipose cells into brown fat tissue.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-326)
Fournisseur:
ProSci Inc.
Description:
Zinc-alpha-2-glycoprotein (ZAG), first identified in the 1960s, derives its name from its precipitation from human plasma upon the addition of zinc salts. ZAG has since been found in secretory epithelial cells and in a range of body fluids. ZAG is identical to a lipid mobilizing factor isolated from the urine of patients with cancer cachexia and stimulates lipolysis in in vitro and in vivo experiments. Due to its expression in, and secretion from adipocytes, ZAG is considered an adipokine. Recently the clinical significance of ZAG has been clarified. ZAG expression in adipocytes is inversely related to fat mass, thus it is intimately involved in the maintenance of body weight in mice and humans. Epidemiological studies have uncovered an association between ZAG and plasma cholesterol. The non-synonymous single nucleotide polymorphism rs4215 in ZAG is associated with plasma cholesterol and obesity. Structurally ZAG possesses a class I major histocompatibility complex (MHC) protein fold. It is distinct from other members of this protein family in that it is soluble, rather than being anchored to plasma membranes, and it associates with prolactin inducible protein rather than beta2-microglobulin. Similar to peptide antigen-presenting class I MHC molecules, ZAG possesses an open apical groove between its alpha1 and alpha2 domain helices.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI4441P)
Fournisseur:
ProSci Inc.
Description:
ATG5 peptide is used for blocking the activity of ATG5 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4451P)
Fournisseur:
ProSci Inc.
Description:
SCRAPPER peptide is used for blocking the activity of SCRAPPER antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-513)
Fournisseur:
ProSci Inc.
Description:
Leptin receptor (LEPR) is also known as LEP-R, cluster of differentiation 295 (CD295), OB-R and B219, is a single-transmembrane-domain receptor of the gp130 family of cytokine receptors. Leptin receptor exists as homodimer and binds Leptin with high affinity, thus mediates the biological function of the adipocyte-specific hormone Leptin. LEPR is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this protein have been associated with obesity and pituitary dysfunction. Interaction of leptin and leptin receptor is crucial for body weight and bone mass regulation in mammals through hypothalamic effects on satiety and energy expenditure. Meanwhile, research data supports a leptin receptor activation model based on ligand-induced conformational changes.
UOM:
1 * 1 EA
Fournisseur:
Shenandoah Biotechnology
Description:
Sonic hedgehog (SHH) is a member of a small group of hedgehog secreted proteins that are essential for development in both vertebrates and invertebrates. There are three mammalian hedgehog homologues, sonic, desert, and indian, that signal via the Patched-1 and Patched-2 receptors. SHH is a morphogen that is essential during vertebrate organogenesis and adult stem cell division.
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