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Protéines et Peptides
Numéro de catalogue:
(PRSI91-617)
Fournisseur:
ProSci Inc.
Description:
Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6909P)
Fournisseur:
ProSci Inc.
Description:
BMP15 peptide is used for blocking the activity of BMP15 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6919P)
Fournisseur:
ProSci Inc.
Description:
DELE peptide is used for blocking the activity of DELE antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5831P)
Fournisseur:
ProSci Inc.
Description:
FREM2 peptide is used for blocking the activity of FREM2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5827P)
Fournisseur:
ProSci Inc.
Description:
ZEB2 peptide is used for blocking the activity of ZEB2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6223P)
Fournisseur:
ProSci Inc.
Description:
MYOZAP peptide is used for blocking the activity of MYOZAP antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4019P)
Fournisseur:
ProSci Inc.
Description:
BANF1 peptide is used for blocking the activity of BANF1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-571)
Fournisseur:
ProSci Inc.
Description:
Leucine-Rich Repeat-Containing Protein 3B (LRRC3B) belongs to the LRRC3 family. LRRC3B is single-pass membrane protein and contains three leucine-rich repeats, one LRRCT domain, and one LRRNT domain. LRR-containing proteins, of which there are greater than 2,000, participate in many important processes, including plant and animal immunity, hormone-receptor interactions, cell adhesion, signal transduction, regulation of gene expression, and apoptosis. A number of microarray expression profiling studies on human cancers have shown that LRRC3B is down-regulated in gastric, breast, colon, testis, prostate and brain cancers, suggesting LRRC3B involvement in carcinogenesis
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-575)
Fournisseur:
ProSci Inc.
Description:
Mouse Leukemia inhibitory factor（lif）is a secreted protein which belongs to the LIF/OSM family.LIF has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. it has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-274)
Fournisseur:
ProSci Inc.
Description:
Peroxiredoxin-1(PRDX1) contains 1 thioredoxin domain and belongs to the AhpC/TSA family. PRDX1 constitutively expressed in most human cells and it is induced to higher levels upon serum stimulation in untransformed and transformed cells. PRDX1 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin and play an important role in eliminating peroxides generated during metabolism. PRDX1 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. It reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. It may contribute to the antiviral activity of CD8(+) T-cells and have a proliferative effect in cancer development or progression.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-287)
Fournisseur:
ProSci Inc.
Description:
Protachykinin-1(TAC1) is a secreted protein and belongs to the tachykinin family. TAC1 is encoded by the TAC1 gene. This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-288)
Fournisseur:
ProSci Inc.
Description:
Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-033)
Fournisseur:
ProSci Inc.
Description:
FGF acidic is a 17 kDa nonglycosylated member of the FGF family of mitogenic peptides. FGF acidic, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4033P)
Fournisseur:
ProSci Inc.
Description:
DRAM peptide is used for blocking the activity of DRAM antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-375)
Fournisseur:
ProSci Inc.
Description:
Interferon gamma receptor 1(IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5859P)
Fournisseur:
ProSci Inc.
Description:
CaBP7 peptide is used for blocking the activity of CaBP7 antibody.
UOM:
1 * 50 µG
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