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Protéines et Peptides
Numéro de catalogue:
(PRSI6095P)
Fournisseur:
ProSci Inc.
Description:
ZIP8 peptide is used for blocking the activity of ZIP8 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6117P)
Fournisseur:
ProSci Inc.
Description:
WIZ peptide is used for blocking the activity of WIZ antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-588)
Fournisseur:
ProSci Inc.
Description:
Human EN-RAGE belongs to the S100/calgranulin superfamily. There are at least 21 different S100 proteins and the protein is 100% soluble in ammonium sulfate at neutral pH. S100 proteins play a role in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response.Human EN-RAGE is characterized by two EF-hand calcium-binding motifs, zinc- and copper-binding protein.S100A12 is a disulfide-linked homodimer and the interface between the two subunits is composed mostly of hydrophobic residues.Its proinflammatory activity involves recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. EN-RAGE acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to receptor for advanced glycation endproducts (AGER). Binding to AGER activates the MAP-kinase and NF-kappa-B signaling pathways leading to production of proinflammatory cytokines and up-regulation of cell adhesion molecules ICAM1 and VCAM1. It also acts as a monocyte and mast cell chemoattractant. Moreover, it can stimulate mast cell degranulation and activation which generates chemokines, histamine and cytokines inducing further leukocyte recruitment to the sites of inflammation. It can inhibit the activity of matrix metalloproteinases; MMP2, MMP3 and MMP9 by chelating Zn2+from their active sites.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-218)
Fournisseur:
ProSci Inc.
Description:
Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e. g. platelets) with prothrombin or coagulation factors and inhibits the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the 'annexin V affinity assay' to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-215)
Fournisseur:
ProSci Inc.
Description:
FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. Is involved in cytotoxic T cell mediated apoptosis and in T cell development.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-937)
Fournisseur:
ProSci Inc.
Description:
Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-374)
Fournisseur:
ProSci Inc.
Description:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI40-583-25UG)
Fournisseur:
ProSci Inc.
Description:
Rat Recombinant Carboxypeptidase-B (from E. coli)
UOM:
1 * 0,25 mg
Fournisseur:
Shenandoah Biotechnology
Description:
Bone morphogenetic protein 2 (BMP-2) is a member of the bone morphogenetic protein (BMP) family and functions as a potent inducer of bone and cartilage development. BMP proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. Active BMP-2 consists of forming a homodimer or a heterodimer with a related BMP, such as BMP-7. BMP-2 signals through type I and type II receptor tyrosine kinases in conjuction with SMAD proteins to directly promote osteoblast differentiation. BMP-2 is also important during cardiac development and supports epicardial cell migration.
Fournisseur:
Merck Millipore (Calbiochem)
Description:
Caspase-3 inhibitor III
Fournisseur:
Merck Millipore (Oncogene)
Description:
Streptavidin
Numéro de catalogue:
(431784-5)
Fournisseur:
Merck Millipore (Calbiochem)
Description:
PHA-L is a potent lymphocyte mitogen with a narrow range. Requires calcium and manganese ions for activity. It has also been found to be useful as a specific marker in anterograde neuronal tracing.
UOM:
1 * 5 mg
Numéro de catalogue:
(420307-50)
Fournisseur:
Merck Millipore (Calbiochem)
Description:
Native kallikrein from human plasma. A serine protease that releases bradykinin from kininogen. Present in the plasma as an inactive precursor, prokallikrein.
UOM:
1 * 50 µG
Fournisseur:
Merck Millipore (Calbiochem)
Description:
Human albumin (from serum)
Fournisseur:
Merck Millipore (Calbiochem)
Description:
Human albumin (from serum)
Numéro de catalogue:
(J61170.MB)
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