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Protéines et Peptides
Fournisseur:
Shenandoah Biotechnology
Description:
Interferon-alpha 2b (IFN-α 2b) is a type I interferon made by leukocytes during viral infection. The JAK-STAT pathway mediates the antiviral and anti-cell proliferation activities of IFN-α 2b. IFN-α proteins are widely used as standard treatments during antiviral and antineoplastic therapies. The IFN-α 2b variant differs from IFN-α 2a by one amino acid.
Fournisseur:
Shenandoah Biotechnology
Description:
Leukemia inhibitory factor (LIF) is a member of the interleukin 6 (IL-6) family that is made by a variety of adult and embryonic tissues. LIF signals through the glycoprotein 130 (gp130)/LIF receptor (LIFR) heterodimer to activate STAT3 and MAPK signaling. LIF functions during hematopoietic differentiation, neuronal cell differentiation, kidney development, and inflammatory processes. Human LIF may also be an important factor during human embryonic stem cell (hESC) self-renewal, pluripotency, and embryonic implantation.
Fournisseur:
Shenandoah Biotechnology
Description:
Interleukin 17F (IL-17F), a member of the IL-17 cytokine family, is secreted by activated CD4+ T cells and monocytes. IL-17F binds the IL-17 receptor related molecule, IL17RC, to promote the production of the interleukin 6 (IL-6), interleukin 8 (IL-8), and granulocyte macrophage colony-stimulating factor (GM-CSF) cytokines. IL-17F also functions to regulate matrix turnover rates, inhibit endothelial cell angiogenesis, and induce the endothelial cell expression of interleukin 2 (IL-2), monocyte chemoattractant protein-1 (MCP-1), and transforming growth factor beta 1 (TGF-β1).
Fournisseur:
Shenandoah Biotechnology
Description:
Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes. IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages.
Fournisseur:
Shenandoah Biotechnology
Description:
Ciliary neurotrophic factor (CNTF) is a neurotrophic factor that promotes the survival of neuronal cell populations, neurite outgrowth, and neurotransmitter synthesis.CNTF also plays an important protective role during nervous system injury.
Fournisseur:
Shenandoah Biotechnology
Description:
Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte proliferation, terminal differentiation, and activation. G-CSF synthesis occurs in monocyte, macrophage, epithelial, endothelial, and fibroblast cells after activation by bacterial endotoxins, tumor necrosis factor alpha (TNF-α), interleukin 1 (IL-1), or interleukin 17 (IL-17).
Fournisseur:
Shenandoah Biotechnology
Description:
Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells.
Numéro de catalogue:
(J62428.MA)
Fournisseur:
Thermo Scientific
Description:
Streptavidin (from <i>Streptomyces avidinii</i>)
UOM:
1 * 10 mg
Numéro de catalogue:
(344220-5)
Fournisseur:
Merck Millipore (Calbiochem)
Description:
The formyl peptide receptor-like 1 antagonist, WRW controls the biological activity of formyl peptide receptor-like 1 (FRPL1).
UOM:
1 * 5 mg
Numéro de catalogue:
(110175-1)
Fournisseur:
Merck Millipore (Calbiochem)
Description:
Acetyl-Pepstatin
UOM:
1 * 1 mg
Fournisseur:
Merck Millipore (Calbiochem)
Description:
Leupeptin hemisulphate
Fournisseur:
Merck Millipore (Calbiochem)
Description:
Soy bean trypsin inhibitor
Fournisseur:
Merck Millipore (Calbiochem)
Description:
Antipain Dihydrochloride
Numéro de catalogue:
(374805-1)
Fournisseur:
Merck Millipore (Oncogene)
Description:
Hemocyanin is a large, multi-subunit, oxygen-carrying, metalloprotein that is used as a carrier protein in the production of antibodies.
UOM:
1 * 1 g
Numéro de catalogue:
(553506-50)
Fournisseur:
Merck Millipore (Calbiochem)
Description:
Recombinant humman Receptor-associated Protein (RAP) fused to GST, expressed in <i>E. coli</i> and subsequently cleaved with thrombin to remove GST. Antagonizes the ligand binding of certain members of the low-density lipoprotein receptor family such as low density lipoprotein receptor-related protein (LRP) and very low-density lipoprotein (VLDL) receptor. Promotes the proper folding and subsequent exocytic trafficking of the wild-type low density lipoprotein receptor (LDLR) and several of its class 2 mutants. Expressed as a GST-fusion protein that is subsequently cleaved with thrombin. Typical concentrations to block LRP or VLDL receptor are 200-300 nM. For antagonism of LDLR, 1 µM is recommended.
UOM:
1 * 50 µG
Numéro de catalogue:
(407615-5)
Fournisseur:
Merck Millipore (Calbiochem)
Description:
Recombinant, human interleukin-1ß expressed in <i>E. coli</i><B><i>. </i></B>Major form of interleukin-1 secreted by monocytes and macrophages. Induces nitric oxide synthase in pancreatic and smooth muscle cells and suppresses apoptosis in rat ovarian follicles. Involved in inflammatory and immune responses and promotes wound healing.
UOM:
1 * 5 µG
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