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Protéines et Peptides
Fournisseur:
Shenandoah Biotechnology
Description:
Monocyte chemotactic protein 2 (MCP-2), also known as CCL8, is a cytokine that is important during allergic and inflammatory responses. MCP-2 activates mast cells, eosinophils, and basophils through the G protein-coupled chemokine receptors CCR1, CCR2B, and CCR5. MCP-2 signaling through the CCR5 receptor also functions as a natural inhibitor of the human immunodeficiency virus, type 1 (HIV-1).
Fournisseur:
Shenandoah Biotechnology
Description:
Insulin-like growth factor I (IGF-I) is a growth factor that is produced by the liver. IGF-1 production is stimulated by growth hormone (GH). IGF-I binds the insulin-like growth factor 1 receptor (IGF1R) and the insulin receptor to stimulate systemic body growth. IGF-I is one of the most potent activators of the AKT signaling pathway, which stimulates cell proliferation and inhibits programmed cell death. Mature human IGF-I is 100% homologous to bovine and porcine IGF-1 proteins.
Numéro de catalogue:
(PRSI6655P)
Fournisseur:
ProSci Inc.
Description:
KPNA5 peptide is used for blocking the activity of KPNA5 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6257P)
Fournisseur:
ProSci Inc.
Description:
DYRK2 peptide is used for blocking the activity of DYRK2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-064)
Fournisseur:
ProSci Inc.
Description:
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-094)
Fournisseur:
ProSci Inc.
Description:
CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-324)
Fournisseur:
ProSci Inc.
Description:
Betatrophin (RIFL; Lipasin; Angiopoietin-like protein 8 (ANGPTL8)) is a newly discovered secreted protein of 198 aa that was proposed to promote beta cell proliferation and improve glucose tolerance in mice. Betatrophin may also function in inhibition of lipase activity and on serum triglyceride regulation. Betatrophin is expressed in the liver and in white and brown adipose tissue of mice. In humans, betatrophin is found to be predominantly expressed in the liver. Betatrophin levels are reduced by fasting and are elevated upon insulin resistance and during pregnancy. Betatrophin, according to preliminary data could bind to the macrophage receptor Marco and also to RTN4R, a neuronal receptor. Recently, a study using ANGPTL8 KO mice showed that ANGPTL8/Betatrophin does not play a role in beta cell proliferation nor in glycemic control as previously thought, but regulates plasma triglyceride levels.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI6013P)
Fournisseur:
ProSci Inc.
Description:
ATG9A peptide is used for blocking the activity of ATG9A antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3887P)
Fournisseur:
ProSci Inc.
Description:
PAK2 peptide is used for blocking the activity of PAK2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6015P)
Fournisseur:
ProSci Inc.
Description:
PLAC1 peptide is used for blocking the activity of PLAC1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5989P)
Fournisseur:
ProSci Inc.
Description:
KPNA5 peptide is used for blocking the activity of KPNA5 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-470)
Fournisseur:
ProSci Inc.
Description:
Ephrin Type-A Receptor 7 (EPHA7) is a single-pass type I membrane protein which belongs to the Eph family of transmembrane receptor tyrosine kinases. It contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile alpha motif) domain. EPHA7 is a receptor for members of the ephrin-A family. Eph receptors are largely expressed throughout the ectoderm, mesoderm, and endoderm of vertebrate embryos. EPHA7 functions as a repulsive guidance molecule during the targeting of retinal axons to the superior colliculus and of neocortical axons to the thalamus. EPHA7 is expressed at a substantial level in most human lung cancers. The high expression of EPHA7 protein may participate in the malignancy transformation, invasion progression and metastasis of primary hepatocellular carcinoma. EPHA7 may involve in smoking related lung carcinogenesis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4453P)
Fournisseur:
ProSci Inc.
Description:
Slitrk1 peptide is used for blocking the activity of Slitrk1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4455P)
Fournisseur:
ProSci Inc.
Description:
Slitrk1 peptide is used for blocking the activity of Slitrk1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3917P)
Fournisseur:
ProSci Inc.
Description:
Avian influenza nonstructural protein 2 peptide is used for blocking the activity of avian influenza nonstructural protein 2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3905P)
Fournisseur:
ProSci Inc.
Description:
TRPC3 peptide is used for blocking the activity of TRPC3 antibody.
UOM:
1 * 50 µG
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